Professor Ipsita Roy
PhD, MSc, BSc
School of Chemical, Materials and Biological Engineering
Professor of Biomaterials
Deputy School Director of Research and Innovation
CDT Co-Director Advanced Biomedical Materials
+44 114 222 5962
Full contact details
School of Chemical, Materials and Biological Engineering
Sir Robert Hadfield Building
Mappin Street
葫芦影业
S1 3JD
- Profile
-
Previously to joining the Department of Material Science and Engineering as Professor of Biomaterials, I was Professor at the School of Life Sciences, University of Westminster, London. I am also Visiting Professor at the National Heart and Lung Institute, Faculty of Medicine, Imperial College London.
I was awarded the prestigious Inlaks Scholarship and the Overseas Research Students Award to study for my PhD at the University of Cambridge. During my time at Cambridge, I was awarded the Churchill College Scholarship, the Lundgren Scholarship, Leche Trust Scholarship and the Cambridge University Philosophical Society Fellowship Award.
My PhD at the Department of Biochemistry was on a B12-dependent enzyme, methylmalonyl-CoA mutase. My postdoctoral work was at the University of Minnesota, USA, at the Bioprocess Technology Institute, where I worked on fatty acid biosynthesis.
Subsequently, I taught at the Indian Institute of Technology, India, for four years as an Assistant Professor. During this time I worked actively on the production of biodegradable polymers from Streptomyces.
I was at the University of Westminster from 2000 until August 2019, where I was the Research Director of the School of Life Sciences and led the Applied Biotechnology Research Group.
I have published over 100 papers in high 鈥業mpact Factor鈥 journals such as Biomaterials, Biomacromolecules, Journal of Royal Society Interface, Acta Biomaterialia and ACS Applied Materials Interfaces, and have presented my work at numerous international conferences.
- Research interests
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Natural Polymers of bacterial origin and their use in medical and environmentally friendly applications.
Her group is currently focussed on the production of novel Polyhydroxyalkanoates (PHAs), a group of FDA-approved natural polymers and their characterisation. She has pioneered the production of PHAs from Gram positive bacteria which lack immunogenic properties and hence are excellent materials for medical applications. Her group is involved in the application of PHAs in the area of hard tissue engineering, soft tissue engineering, wound healing, drug delivery and medical device development. She has also initiated work with bacterial cellulose and 纬-polyglutamic acid, as natural polymers for biomedical applications. PHAs are also environmentally friendly polymers that are biodegradable both in the soil and in the sea. She has recently initiated work related to this aspect of PHAs.
Her work has been funded by the EPSRC, BHF, EU, DuPont, 3D BIONET (MRC), CYCLOPS (EPSRC) and WESTFOCUS, London. Professor Roy has been the scientific coordinator of two large EU projects REBIOSTENT, worth 4.9 million Euros with 14 consortium members and HYMEDPOLY, worth 3.5 million Euros with 12 consortium members. She was also the work package leader of another large EU FP7 project, NEURIMP, worth 4.4 million Euros with 8 consortium members.
Currently, she is work package leader in the H2020: BBI/JU project POLYBIOSKIN worth 3 million Euros with 12 consortium members. All four projects involve the use of PHAs for medical applications, drug eluting biodegradable stents, nerve guidance conduits, antibacterial polymers and wound healing. She is co-PI in the BHF funded Cardiovascular Regenerative Medicine Centre led by Imperial College London. She has received EPSRC funding for the development of smart wound healing patches (CYCLOPS) and drug eluting biodegradable stents.
She was awarded the ICURe, Innovation to Commercialisation, grant worth 拢34,905 from Innovate UK for exploring the commercial potential of Biobased Plastics for Medical Applications. She has an ongoing UKERI project on the development of a 3D disease model for cancer. She has been awarded a H2020: BBI/JU grant, ECOAT, where for the first time she will be exploring the green and environmentally friendly aspect of the PHAs and bacterial cellulose for the development of eco-sustainable multifunctional bio-based coatings with enhanced performance and end of life options. This project is worth 4.6 million and includes 16 partners.
Finally, her most recent grant is from the 3D BIONET and involves the development of 3D cardiac tissue model and includes mathematical modelling in collaboration with the University of Oxford and Imperial College London.
- Publications
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Books
Journal articles
- . New Biotechnology, 83, 133-141.
- . International Journal of Biological Macromolecules, 268, 131476-131476.
- . Drug Discovery Today, 103974-103974.
- . Autophagy Reports, 2(1).
- . Regenerative Biomaterials, 10.
- . Life Sciences, 328, 121871-121871.
- . ACS Chemical Neuroscience, 14(12), 2385-2395.
- . Current Opinion in Biomedical Engineering, 100474-100474.
- . Protein & Peptide Letters, 30.
- . ACS Biomaterials Science & Engineering, 9(3), 1472-1485.
- . Bioscience Reports, 43(2).
- . ACS Chemical Neuroscience, 13(18), 2728-2742.
- . Cancers, 14(14).
- . Materials Letters, 132530.
- . Trends in Molecular Medicine, 28(4), 331-342.
- . Frontiers in Bioengineering and Biotechnology, 9.
- . International Journal of Molecular Sciences, 22(23).
- . Frontiers in Neuroscience, 15.
- . Materials, 14(17).
- . ACS Appl Mater Interfaces.
- . Materials Science and Engineering: R: Reports, 145.
- . Bioengineering & Translational Medicine.
- . Frontiers in Bioengineering and Biotechnology, 9, 663764.
- . Applied Sciences, 11(9).
- . Frontiers in Bioengineering and Biotechnology, 9.
- . Polymers (Basel), 13(7).
- . Frontiers in Bioengineering and Biotechnology, 9(1).
- . ACS Biomaterials Science & Engineering, 7(2), 672-689.
- . International Journal of Molecular Sciences, 21(24).
- . Frontiers in Bioengineering and Biotechnology, 8.
- . Journal of Functional Biomaterials, 11(3).
- . Frontiers in Bioengineering and Biotechnology, 8.
- . Ceramics International.
- . Frontiers in Bioengineering and Biotechnology, 8.
- . Materials, 13(11).
- . Frontiers in Bioengineering and Biotechnology, 8.
- . Journal of Functional Biomaterials, 11(2).
- . Polymers, 12(1).
- . ACS Omega, 4(22), 19746-19755.
- . Biochemical Engineering Journal, 150, 107283-107283.
- . Journal of Tissue Engineering and Regenerative Medicine, 13(9), 1581-1594.
- . Chemistry of Materials, 31(15), 5450-5463.
- . Expert Review of Medical Devices, 16(6), 467-482.
- . Osteoarthritis and Cartilage, 27, S432-S433.
- . Journal of Materials Science: Materials in Medicine, 29(12).
- . ACS Applied Materials & Interfaces, 10(30), 25056-25068.
- . Acta Biomaterialia, 71, 225-234.
- . Journal of Materials Science: Materials in Medicine, 29(3).
- . Journal of Tissue Engineering and Regenerative Medicine, 12(1), e495-e512.
- . Microbial Biotechnology, 10(6), 1384-1399.
- . Carbohydrate Polymers, 171, 220-228.
- . Journal of Chemical Technology & Biotechnology, 92(7), 1548-1557.
- . International Journal of Polymeric Materials and Polymeric Biomaterials, 66(7), 326-335.
- . Macromolecular Materials and Engineering, 301(8), 922-934.
- . Macromolecular Materials and Engineering, 301(8), 881-881.
- . Polymer International, 65(7), 780-791.
- . Journal of Biomaterials Applications, 31(1), 77-91.
- . Polymer International, 65(7), 741-746.
- . Polymer International, 65(6), 661-674.
- . Journal of Nanomaterials, 2016, 1-14.
- . Carbohydrate Polymers, 126, 47-51.
- . Journal of Chemical Technology & Biotechnology, 90(7), 1167-1168.
- . Journal of Chemical Technology & Biotechnology, 90(7), 1209-1221.
- . Engineering in Life Sciences, 15(6), 612-621.
- . Journal of Biomaterials and Nanobiotechnology, 05(04), 229-240.
- . Enzyme and Microbial Technology, 61-62, 61-66.
- . Journal of Materials Science: Materials in Medicine, 24(12), 2809-2817.
- . Expert Opinion on Drug Delivery, 10(10), 1353-1365.
- . Journal of Molecular Microbiology and Biotechnology, 23(6), 391-395.
- , 397-421.
- . Reactive and Functional Polymers, 73(10), 1340-1348.
- . Bioinspired, Biomimetic and Nanobiomaterials, 2(3), 141-153.
- . Advanced Engineering Materials, 14(6), B330-B343.
- . Biotechnology Journal, 7(2), 293-303.
- Polyhydroxyalkanoates: The emerging new green polymers of choice. RSC Green Chemistry, 79-101.
- . Journal of Applied Electrochemistry, 41(8), 919-923.
- . Biomacromolecules, 12(6), 2126-2136.
- . Biotechnology Letters, 33(5), 985-991.
- . Materials Science and Engineering: R: Reports, 72(3), 29-47.
- . Scanning, 33(2), 59-68.
- . Applied Microbiology and Biotechnology, 88(1), 65-73.
- . Current Opinion in Microbiology, 13(3), 321-326.
- . Journal of Chemical Technology & Biotechnology, 85(6), 731-731.
- . Biomaterials, 31(10), 2806-2815.
- . Journal of The Royal Society Interface, 7(44), 453-465.
- . Acta Biomaterialia, 6(3), 735-742.
- . Acta Biomaterialia, 6(7), 2773-2786.
- . Materials Chemistry and Physics, 118(2-3), 420-426.
- . Journal of Tissue Engineering and Regenerative Medicine, 3(2), 139-148.
- . Journal of Applied Microbiology, 107(4), 1131-1139.
- . Biomacromolecules, 10(4), 691-699.
- . Journal of The Royal Society Interface, 6(33), 401-409.
- . Biotechnology Letters, 30(9), 1665-1670.
- . Journal of Applied Microbiology, 104(6), 1624-1635.
- . Biomaterials, 29(12), 1750-1761.
- . Metabolomics, 4(1), 52-62.
- . Journal of Molecular Catalysis B: Enzymatic, 50(2-4), 114-120.
- . Journal of Biotechnology, 132(3), 251-258.
- Biodegradable polymer coated 45S5 Bioglass-derived glass-ceramic scaffolds for bone tissue engineering. Glass Technology: European Journal of Glass Science and Technology Part A, 48(5), 227-234.
- . Journal of Biotechnology, 131(4), 397-403.
- . Biomacromolecules, 8(7), 2112-2119.
- Fighting protein misfolding diseases. Pharmaceutical Technology Europe, 19(6), 34-44.
- . Enzyme and Microbial Technology, 40(6), 1518-1523.
- . Journal of Chemical Technology & Biotechnology, 82(3), 233-247.
- . Nanotechnology, 18(7), 075701-075701.
- . Journal of Biotechnology, 127(3), 475-487.
- . Antonie van Leeuwenhoek, 91(1), 1-17.
- . Expert Review of Medical Devices, 3(6), 853-868.
- . Biomacromolecules, 7(8), 2249-2258.
- . Biomaterials, 27(7), 964-973.
- . Biochemical Engineering Journal, 23(3), 193-198.
- . Journal of Chromatography A, 1069(2), 155-161.
- . Enzyme and Microbial Technology, 34(1), 26-32.
- , 159-189.
- . Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1647(1-2), 361-366.
- . Archives of Microbiology, 179(1), 66-69.
- . Journal of Bacteriology, 180(18), 4828-4833.
- A methylmalonyl-CoA mutase in Escherichia coli?. Protein Engineering, 10(3333), 68.
- . FEBS Letters, 394(2), 126-128.
- . Journal of Bacteriology, 174(17), 5763-5764.
- . ACS Biomaterials Science & Engineering.
- . NeuroMolecular Medicine, 26(1).
- . Tissue Engineering Part A.
- . Macromolecular Bioscience.
- . International Materials Reviews, 1-39.
- . The FEBS Journal.
- . Journal of Functional Biomaterials, 14(1), 40-40.
- . International Journal of Molecular Sciences, 24(2), 986-986.
- . Biomaterials Science.
- . RSC Sustainability.
- . Applied Microbiology and Biotechnology.
- . Journal of Industry, Competition and Trade.
- . Frontiers in Molecular Biosciences, 9.
- . Tissue Engineering Part B: Reviews.
- . Nanomaterials, 11(1), 62-62.
- . Frontiers in Cardiovascular Medicine, 7.
- . Chemical and Biochemical Engineering Quarterly, 29(2), 157-172.
- . International Journal of Molecular Sciences, 12(7), 4294-4314.
- . Advanced Engineering Materials, 12(7), B260-B268.
- . Journal of Chemical Technology & Biotechnology, 85(6), 732-743.
- . Journal of Chemical Technology & Biotechnology, 85(6), 760-767.
- . Biomedical Materials.
- . Journal of Functional Biomaterials, 11(3), 62-62.
Chapters
- , Cellular Osmolytes (pp. 1-16). Springer Nature Singapore
- , Some Key Topics in Chemistry and Biochemistry for Biotechnologists (pp. 44-63). CRC Press
- , Recent Advances in Pharmaceutical Innovation and Research (pp. 3-40). Springer Nature Singapore
- , Pluripotent Stem Cell Therapy for Diabetes (pp. 221-250). Springer International Publishing
- , Three Phase Partitioning (pp. 197-222). Elsevier
- , Three Phase Partitioning (pp. 175-196). Elsevier
- , The Handbook of Polyhydroxyalkanoates (pp. 255-284). CRC Press
- , Advances in Microbial Physiology (pp. 89-138). Elsevier
- , Polymers and Polymeric Composites: A Reference Series (pp. 1131-1148). Springer International Publishing
- , Gene Therapy in Neurological Disorders (pp. 207-228). Elsevier
- , Polymers and Polymeric Composites: A Reference Series (pp. 1-18). Springer International Publishing
- , Foundations of Economic Change (pp. 357-391). Springer International Publishing
- , Science and Principles of Biodegradable and Bioresorbable Medical Polymers (pp. 257-277). Elsevier
- Polyhydroxyalkanoates: A new generation of biotechnologically produced biodegradable polymers, Biodegradable Materials: Production, Properties and Applications (pp. 173-215).
- Polyhydroxyalkanoates: A new generation of biotechnologically produced biodegradable polymers, Biotechnology: Research, Technology and Applications (pp. 1-46).
- , Methods for Affinity-Based Separations of Enzymes and Proteins (pp. 1-15). Birkh盲user Basel
- , Methods for Affinity-Based Separations of Enzymes and Proteins (pp. 130-147). Birkh盲user Basel
- , Biomaterials from Nature for Advanced Devices and Therapies (pp. 337-383). John Wiley & Sons, Inc.
Conference proceedings papers
- Tissue repair with multimaterial biomedical devices fabricated from sustainable biopolymers. TISSUE ENGINEERING PART A, Vol. 29(13-14)
- Polyhydroxyalkanoates: A family of natural polymers, for medical implant development and disease modelling. Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, Vol. 40 (pp 760)
- Polyhydroxyalkanoates, ideal materials for cardiac regeneration. Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, Vol. 40 (pp 442)
- Nerve Tissue Engineering using Blends of Polyhydroxyalkanoates for Peripheral Nerve Regeneration. TISSUE ENGINEERING PART A, Vol. 21 (pp S325-S325)
- PERIPHERAL NERVE REGENERATION USING BLENDS OF POLYHYDROXYALKANOATES. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, Vol. 20(2) (pp 185-185)
- (pp 159-175)
- . Chemical Engineering Transactions, Vol. 32 (pp 931-936)
- . Journal of Applied Polymer Science, Vol. 122(6) (pp 3606-3617)
- Production of medium chain length polyhydroxyalkanoates in recombinant Bacillus subtilis. 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials
- Production of polyhydroxyalkanoates by pseudomonas mendocina using vegetable oils as the sole carbon source. 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials
- Polyhydroxyalkanoate (PHA)/Bacterial Cellulose composites for biomedical applications. 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials
- . V INTERNATIONAL CONFERENCE ON TIMES OF POLYMERS (TOP) AND COMPOSITES
- Optimisation of bioglass庐-derived scaffolds for bone tissue engineering. 8th World Biomaterials Congress 2008, Vol. 3 (pp 1262)
- Nano- versus micron-sized bioactive glass reinforcement of P(3HB) - Are nano-fillers the way forward?. 8th World Biomaterials Congress 2008, Vol. 2 (pp 863)
Preprints
- Research group
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Research Associates:
PhD students:
- Isabel Orlando (submitted) Novel hydrogel-based hybrid antibacterial polymers for wound healing applications (University of Westminster)
- Sheila Piarali (submitted) Novel Antibacterial Agents for Innovative Antibacterial Polymers (University of Westminster)
- Alexandra Paxinou (in progress) Novel Antibacterial Polymers of Natural Origin (University of Westminster)
- Elena Marcello (in progress) PHA based Antibacterial Polymers for Tissue Engineering (University of Westminster)
- Qasim Majid (in progress) PHA based regeneration of cardiac tissue (Second Supervisor, in collaboration with Professor Sian Harding, Imperial College London)
- Maria Leite (in progress) The Biology of the surface of Mars (Second Supervisor, in collaboration with Professor Lewis Dartnell, University of Westminster)
- Rebecca Barthenilla Garcia (in progress) Production of PHAs using sustainable biomass (Second Supervisor, in collaboration with Professor Lewis Dartnell, University of Westminster)
- Anabelle Fricker (University of 葫芦影业)
- Emmanuel Asare (University of 葫芦影业)
- Teaching interests
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- Organic Chemistry
- Biochemistry
- Molecular Biology
- Biomaterials
- Bioengineering
- Tissue Engineering
- Regenerative Medicine
- Biotechnology
- Drug Delivery
- Professional activities and memberships
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- Editor of the Journal of Chemical Technology and Biotechnology (JCTB)
- Previously special editor of two In Focus Issues of JCTB on Biodegradable polymers and Controlled Drug Delivery
- Grant reviewing panels for:
- Biotechnology and Biological Sciences Research Council (BBSRC)
- Engineering and Physical Sciences Research Council (EPSRC)
- Natural Sciences and Engineering Research Council of Canada
- Austrian Science Fund (Fonds zur F枚rderung der wissenschaftlichen Forschung, FWF), Austria
- National Natural Science Foundation of China
- European Social Fund
- MUIR
- Best Chemistry Undergraduate Student Award, St. Stephen's College, 1984, 1985, 1986
- Professor Seshadri Prize for being the best candidate in the BSc (Hons) Chemistry, University of Delhi, 1986
- Best Biotechnology Masters Student Award, Jawaharlal Nehru University, New Delhi, 1988
- Overseas Research Studentship from the Committee of Vice Chancellors and Principals, UK, 1989-1991
- The Inlaks Scholarship, India, for doctoral studies at Cambridge, 1989-1990
- Churchill College Scholarship, University of Cambridge, UK, 1991
- Lundgren Scholarship, University of Cambridge, UK, 1992
- Leche Trust Scholarship, London, UK, 1992
- Cambridge University Philosophical Society Fellowship Award, Cambridge, UK, 1992
- Nominated member of the New York Academy of Sciences in recognition of research activities, 1997
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