Professor Stephen Matcher
PhD, BSc
School of Electrical and Electronic Engineering
Professor of Biophotonics
- Profile
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I graduated from Imperial College London with a BSc in Physics and subsequently a PhD in optical astronomy, where I used high-speed, low-light-level imaging to overcome atmospheric turbulence and achieve diffraction-limited ground-based imaging.
I translated my expertise in low-light-level imaging into medicine at University College London, where I developed near-infrared spectroscopy techniques to study tissue oxygen delivery, especially in newborn infants at risk from birth asphyxia.
I joined the staff of the Physics department at the University of Exeter, where I established research programmes in visible light spectroscopy of skin and optical coherence tomography (OCT).
In 2006 I joined the University of 葫芦影业 where I am currently Professor of Biophotonics.
My chief research interest lies in the development and application of novel biophotonic imaging tools to aid the characterisation of native and engineered biological tissues.
I work extensively with optical coherence tomography (OCT), including novel variants such as polarization-sensitive OCT for the non-invasive assessment of collagen organization and OCT angiography for the measurement of tissue vascularization.
I also develop novel microscopy tools based on second harmonic generation (SHG) and novel clinical sensors based on fluorescence.
I am currently collaborating with clinical colleagues to improve the detection of bacterial and fungal eye infections, to provide tools for the early prediction of pre-term birth to develop non-invasive tools, to characterise skin barrier function and assess inflammatory skin disorders such as atopic dermatitis and to determine the biomechanical factors affecting the interaction between skin and man-made objects.
- Qualifications
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- PhD in optical astronomy, Imperial College, London
- BSc in Physics, Imperial College, London
- Research interests
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- Biophotonics
- Medical Imaging
- OCT
- Publications
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Books
Journal articles
- Identification and Quantification of Intrinsic Optical Contrast for Near-infrared Mammography. Photochemistry and Photobiology, 67(1), 4-4.
Chapters
Conference proceedings papers
2 measurements in layered media. Optics InfoBase Conference Papers (pp 83-91)
Absolute SO
- Teaching activities
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- Module leader (BIE291 Biomedical Instrumentation)
- Module instructor (EEE228 Design Project)
- Professional activities and memberships
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- Bioengineering personal tutor
- Foundation Year personal tutor
- Research students
Student Degree Status Primary/Secondary Byers R A PhD Graduated Primary Li, W PhD Graduated Primary Lin, W C PhD Graduated Primary Yuan, R PhD Current Primary Duan, T PhD Current Primary Williams, S PhD Current Secondary Hooper, S PhD Current Primary Sasi, G PhD Current Secondary