@article{article, title = {{SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocols}}, publisher = {{Elsevier BV}}, url = {{https://doi.org/10.1016/j.eclinm.2024.102988 }}, year = {{2025}}, month = {{1}}, author = {{Ursino M and Villacampa G and Rekowski J and Dimairo M and Solovyeva O and Ashby D and Berlin J and Boix O and Calvert M and Chan A-W and Coschi CH et al}}, doi = {{10.1016/j.eclinm.2024.102988}}, volume = {{79}}, journal = {{eClinicalMedicine}}, pages = {{102988-102988}}, note = {{Accessed on 2025/02/05}}}