James Fotheringham
Population Health, School of Medicine and Population Health
Consultant Nephrologist and Honorary Senior Lecturer
+44 114 222 4346
Full contact details
Population Health, School of Medicine and Population Health
Regent Court (ScHARR)
30 Regent Street
ºù«Ӱҵ
S1 4DA
- Profile
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I am a Consultant Nephrologist at the ºù«Ӱҵ Kidney Institute, and a clinical academic at ScHARR where I perform research into the health economics of renal disease, supervise PhD students, and undertake a range of knowledge exchange activities for industry and other sectors.
I am passionate about data. During my PhD (2010-2013) funded by using data from and collaborating with the I was able for the first time to link registry data to data to undertake a range of analyses. This research is used as a case study by , the and to highlight the value of secondary data analysis and data linkage.
I have received national junior investigator awards from the and for analyses arising from this project leading to an to fund my continued research into the associated with the two-day break in patients receiving three times a week haemodialysis.
I have been involved in a number of other renal studies including the UK-Catheter study (an ancillary study to the ) , and the trial, collaborating with others I have published on albuminuria, obesity and renal bone disease, often championing the use of existing trial and cohort study datasets.
Outside of kidney disease, was part of the group who undertook the statistical appraisal of for the Department of Health/NHS Information Centre. I joined the National Institute of Health and Care Excellence as a committee member in 2021 and was appointed as Vice Chair of in 2022, where I routinely draw on my clinical and methodological experience in appraising new healthcare technologies.
My knowledge exchange work has included systematic reviews, primary data collection for a range of purposes including costs and mapping disease-specific measures to the EQ5D, and the conceptualisation, design, population and interpretation of cost-utility models.
- Research interests
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Methods and Instruments
- Within and beyond trial health-economic modelling
- Patient reported outcome and experience measures - Symptom burden, quality of life (utilities), mapping to the EQ5D
- Observational data, secondary use of data and data linkage for epidemiology and comparative effectiveness
- Statistical methods to reduced confounding - Instrumental variables, marginal structural models, G-methods and treatment switching
- Discrete choice experiments
- Systematic review and meta-analysis
Topics
- Health Technology Assessment
- The two-day break in three times as week haemodialysis
- The health economics surrounding renal replacement therapy - In centre haemodialysis (range of formats and settings including intensive frequency/duration and minimal care), peritoneal dialysis, home haemodialysis and transplantation
- Patient centred care, decision making and research prioritisation
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- . The Patient - Patient-Centered Outcomes Research.
- . American Journal of Kidney Diseases, 83(1), 18-27.
- . Acta Dermato-Venereologica, 103.
- . Kidney International Reports.
- . PharmacoEconomics, 41, 457-466.
- . Transplant International, 35.
- . Clinical Journal of the American Society of Nephrology, 17(3), 385-394.
- . Kidney International, 101(3), 615-625.
- . American Journal of Kidney Diseases.
- . PLoS ONE, 16(7).
- . Journal of Internal Medicine, 290(4), 910-921.
- . Kidney International, 99(2), 431-442.
- . Clinical Kidney Journal, 14(2), 665-672.
- . BMC Nephrology, 21(1).
- . Nephrol Dial Transplant, 35(3), 458-464.
- . Medical Decision Making, 39(8), 910-925.
- . BMC Nephrology, 20.
- . Journal of the American College of Cardiology, 73(25), 3259-3266.
- . BMC Nephrology, 18(1).
- . Peritoneal Dialysis International.
- . Nephrology Dialysis Transplantation.
- . Heart, 103(8), 586-591.
- . The European Journal of Health Economics, 17(6), 659-668.
- . Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 35(7), 677-677.
- . Kidney International, 88(3), 569-575.
- . Nephrology Dialysis Transplantation, 30(10), 1726-1734.
- . Hypertension, 65(3), 510-516.
- . Kidney Int, 86(6), 1221-1228.
- . Nephrology Dialysis Transplantation, 29(2), 422-430.
- . American Journal of Kidney Diseases.
- . BMJ, 344, e1001.
- . Nephron Clin Pract, 119(2), c113-c120.
- . Transplantation, 91(9), 991-996.
- . Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis.
- . Nephrology Dialysis Transplantation.
All publications
Journal articles
- . The Lancet, 403(10433), 1279-1289.
- . The Patient - Patient-Centered Outcomes Research.
- . Kidney International Reports.
- . American Journal of Kidney Diseases, 83(1), 18-27.
- . BMC Nephrology, 24(1).
- . Acta Dermato-Venereologica, 103.
- . Kidney International Reports.
- . PharmacoEconomics, 41, 457-466.
- . Kidney International.
- . Platelets, 34(1).
- . PLOS ONE, 17(9).
- . Transplant International, 35.
- . BMJ Open, 12(6).
- . Clinical Journal of the American Society of Nephrology, 17(3), 385-394.
- . Nephrol Dial Transplant.
- . Clinical Kidney Journal, 15(3), 484-499.
- . Kidney International, 101(3), 615-625.
- . American Journal of Kidney Diseases.
- . Journal of Managed Care & Specialty Pharmacy, 27(10), 1495-1499.
- . PLoS ONE, 16(7).
- . Journal of Internal Medicine, 290(4), 910-921.
- . Kidney International, 99(2), 431-442.
- . Clinical Kidney Journal, 14(2), 665-672.
- . BMC Nephrology, 21(1).
- . Nephrol Dial Transplant, 35(3), 458-464.
- . Medical Decision Making, 39(8), 910-925.
- . BMC Nephrology, 20.
- . Journal of the American College of Cardiology, 73(25), 3259-3266.
- . Nephrology,Dialysis and Transplantation.
- . International Journal of Cardiology, 276, 26-30.
- . Journal of Thrombosis and Thrombolysis, 47(4), 520-526.
- . Peritoneal Dialysis International, 38(2), 113-118.
- . BMC Nephrology, 18(1).
- . Peritoneal Dialysis International.
- . Nephrology Dialysis Transplantation.
- . Heart, 103(8), 586-591.
- . Postgrad Med J.
- . Cochrane Database of Systematic Reviews, 2017(1).
- . Journal of Neurosurgery: Pediatrics, 1-7.
- . The European Journal of Health Economics, 17(6), 659-668.
- . Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 35(7), 677-677.
- . Kidney International, 88(3), 569-575.
- . Postgraduate Medical Journal, 91(1079), 492-496.
- . Nephrology Dialysis Transplantation, 30(10), 1726-1734.
- . Hypertension, 65(3), 510-516.
- . Kidney Int, 86(6), 1221-1228.
- . PLoS One, 9(2), e88388.
- . Nephrology Dialysis Transplantation, 29(2), 422-430.
- . Nephrol Dial Transplant, 29(6), 1186-1194.
- . Nephrol Dial Transplant, 29(2), 225-227.
- . American Journal of Kidney Diseases.
- . BMC Health Services Research, 13, 216.
- . BMJ, 344, e1001.
- . The Lancet, 380(9837), 186.
- . Nephron Clin Pract, 119(2), c113-c120.
- . Transplantation, 91(9), 991-996.
- . Nephron Clin Pract, 113(1), c1-c7.
- . Endoscopy, 37(11), 1136-1139.
- . QJM - Monthly Journal of the Association of Physicians, 98(4), 318-319.
- . Health Technology Assessment, 1-45.
- . PLOS ONE, 19(5), e0303299-e0303299.
- . Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis.
- . BMC Nephrology, 25(1).
- . Trials, 24(1).
- . Orphanet Journal of Rare Diseases, 18(1).
- . Cochrane Database of Systematic Reviews, 2023(2).
- . Nephrology Dialysis Transplantation.
Chapters
Conference proceedings papers
- THE VARIATION IN HOSPITALISATION AND MORTALITY FOLLOWING NON-ATTENDANCE FOR HAEMODIALYSIS ACCORDING TO DIALYSIS DAY OF THE WEEK IN A EUROPEAN COHORT: FURTHER EVIDENCE OF HARM FROM THE TWO-DAY BREAK IN THREE TIMES A WEEK HAEMODIALYSIS. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 33
- . Journal of the American College of Cardiology, Vol. 67(13) (pp 1931-1931)
- . Heart, Vol. 101(Suppl 4) (pp A12.1-A12)
- . NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 30
- . Journal of the American College of Cardiology, Vol. 65(10) (pp A1380-A1380)
- . Journal of the American College of Cardiology, Vol. 65(10) (pp A1381-A1381)
- NATIONAL RATES OF ADMISSION, MORTALITY AND POST-PERITONITIS TECHNIQUE SURVIVAL ACCORDING TO DAY OF THE WEEK IN ENGLISH PERITONEAL DIALYSIS PATIENTS. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 29 (pp 223-223)
- Surgical Complication Rates in Patients Receiving Kidney Transplants in England: Analysis by Transplant Centre Using Linked Registry and Hospitalisation Data.. AMERICAN JOURNAL OF TRANSPLANTATION, Vol. 13 (pp 543-544)
- Can HLA Specific Antibody Tests Predict Acute Rejection?. AMERICAN JOURNAL OF TRANSPLANTATION, Vol. 11 (pp 165-165)
- Informed consent for endoscopy: An observational study. GUT, Vol. 52 (pp A23-A23)
Other
- Discussion on the paper by Spiegelhalter, Sherlaw-Johnson, Bardsley, Blunt, Wood and Grigg. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY, 175, 25-47.
Preprints
- Grants
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- NIHR (C): Inter-CEPt: Intervening to eliminate the centre effect variation in home dialysis use, July 2020. £1,110,815
- NIHR (C): A randomised controlled trial assessing the effectiveness and cost effectiveness of thrice weekly, extended, in-centre nocturnal haemodialysis versus standard care using a mixed methods approach, Jan 2020, £2,132,709
- Kidney Research UK (C). The UK Peritoneal Dialysis Outcomes and Practice Patterns Study: UK-PDOPPS – March 2018. £260,000.
- The Health Foundation (C). Scaling up shared care haemodialysis: SHAREHD. £500,000.
- National Institute for Health Research (L). Individualising in centre haemodialysis therapy to reduce the harm caused by the two-day break in the three times a week treatment schedule – Dec 2015. £521,823 over 5 years.
- British Renal Society (C).Qualitative study into intensified haemodialysis regimes – Jan 2015. £15,000.
- Kidney Research UK (L). Travel grant for peritoneal dialysis research – Jan 2015. £2,500.
- National Institute for Health Research (C). Peritoneal Dialysis Outcomes and Practice Patterns Study (UK) – February 2014. £349,989.
- Department of Health (C). Statistical appraisal of Summary Hospital Mortality Indicator – Feb 2011. £66,000.
- Kidney Research UK (L). Clinical Training Fellowship – April 2010. £180,000 over 3 years