Ong, Albert CM, Professor

Professor Albert CM Ong

MA, DM, FRCP, FAoP, FERA

School of Medicine and Population Health

Professor of Renal Medicine

a.ong@sheffield.ac.uk
+44 114 215 9542

The Medical School

Full contact details

Professor Albert CM Ong
School of Medicine and Population Health
The Medical School
Beech Hill Road
��«Ӱҵ
S10 2RX

Profile

For enquiries please contact - SMPH-West-Operational@sheffield.ac.uk

Albert Ong is Professor of Renal Medicine at the University of ��«Ӱҵ, UK. He studied medicine at the University of Oxford and trained as a clinician-scientist at University College London and Oxford. He held senior research fellowships from Kidney Research UK and the Wellcome Trust at Oxford and ��«Ӱҵ. His scientific research focuses on the molecular basis of cyst formation, the genetic basis for disease variability and drug discovery in autosomal dominant polycystic kidney disease (ADPKD). His work has been recognised through national and international awards including the ISN Lillian Jean Kaplan International Prize. He founded and directs specialist services for people with ADPKD and other genetic kidney diseases at the ��«Ӱҵ Kidney Institute. A key opinion leader, he continues to provide strategic advice and leadership in the kidney field. He currently serves as Co-Director of the MRC-NIHR UK Renal Ciliopathies National Network (CILIAREN) and as a member of the ERA Council.

Research interests

ADPKD is the most common genetic disease affecting the kidney with an estimated prevalence of 1 in 1000. It is the fourth most common cause of kidney failure globally and affects around 10% of people on kidney replacement therapy. The mechanisms underlying cyst formation have been intensely studied but remain incompletely understood. The process of cyst formation can be broadly divided into two phases ie cyst initiation and cyst expansion. Variants in two genes, PKD1 and PKD2, account for over 90% of all cases of ADPKD.

The Ong lab aims to develop novel therapies to prevent or inhibit cyst formation in ADPKD by studying the molecular basis underlying cyst initiation and cyst expansion. Our studies around cyst initiation have mainly focussed on investigating the functions of PKD1, PKD2 and related genes or proteins within the PKD1/Polycystin1 network. Work around cyst expansion seeks to elucidate the role of non-coding RNAs and RNA metabolism in disease progression. The lab employs human-derived cellular models, model organisms, experimental models, computational modelling, clinical and genetic data from deeply phenotyped cohorts to study disease mechanisms with a primary focus on clinical translation.

Projects:

Polycystin regulation of actin structure and dynamics through compartmentalised GTPase signalling
Non-coding RNAs as biomarkers of disease activity and as therapeutic targets
RNA-binding proteins as key mediators of disease initiation and progression in ADPKD
Complex genetics underlying very-early onset PKD

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Gittus M, Haley H, Harris T, Borrows S, Padmanabhan N, Gale D, Simms R, Williams T, Acquaye A, Wong A , Chan M et al (2025) . BMC Nephrology, 26(1).
Torres VE, Ahn C, Barten TRM, Brosnahan G, Cadnapaphornchai MA, Chapman AB, Cornec-Le Gall E, Drenth JPH, Gansevoort RT, Harris PC , Harris T et al (2025) . Kidney International, 107(2), 234-254.
Francis A, Harhay MN, Ong ACM, Tummalapalli SL, Ortiz A, Fogo AB, Fliser D, Roy-Chaudhury P, Fontana M, Nangaku M , Wanner C et al (2024) . Nature Reviews Nephrology, 1-13.
Chen EWC, Chong J, Valluru MK, Durkie M, Simms RJ, Harris PC & Ong ACM (2024) . Nephrology Dialysis Transplantation.
Taylor J, Thomas R, Metherall P, van Gastel M, Cornec-Le Gall E, Caroli A, Furlano M, Demoulin N, Devuyst O, Winterbottom J , Torra R et al (2023) . Kidney International Reports.
Perrone RD, Oberdhan D, Ouyang J, Bichet DG, Budde K, Chapman AB, Gitomer BY, Horie S, Ong ACM, Torres VE , Turner AN et al (2023) . Kidney International Reports, 8(5), 989-1001.
Gansevoort RT, Hariri A, Minini P, Ahn C, Chapman AB, Horie S, Knebelmann B, Mrug M, Ong ACM, Pei YPC , Torres VE et al (2022) . American Journal of Kidney Diseases.
Valluru MK, Chung NKX, Gilchrist M, Butland L, Cook J, Takou A, Dixit A, Weedon MN & Ong ACM (2022) . Journal of Medical Genetics.
Ong ACM & Gansevoort RT (2021) . Kidney International, 100(3), 513-515.
Durkie M, Chong J, Valluru MK, Harris PC & Ong ACM (2020) . Genetics in Medicine.
Streets AJ, Prosseda PP & Ong ACM (2020) . JCI Insight, 5(16).
Torres VE & Ong ACM (2020) . Cellular Signalling, 71.
Ong ACM (2018) . Nature Reviews Nephrology, 14(3), 146-148.
Ong ACM (2017) . The Lancet, 389(10081), 1780-1782.
Ong ACM & Harris PC (2015) . Kidney International, 88(4), 699-710.
Ong ACM, Devuyst O, Knebelmann B & Walz G (2015) . The Lancet, 385(9981), 1993-2002.
Ong ACM & Wheatley DN (2003) . Lancet, 361(9359), 774-776.
Cipriani V, Vestito L, Magavern EF, Jacobsen JOB, Arno G, Behr ER, Benson KA, Bertoli M, Bockenhauer D, Bowl MR , Burley K et al () . Nature, 1-9.

All publications

Journal articles

Gittus M, Haley H, Harris T, Borrows S, Padmanabhan N, Gale D, Simms R, Williams T, Acquaye A, Wong A , Chan M et al (2025) . BMC Nephrology, 26(1).
Torres VE, Ahn C, Barten TRM, Brosnahan G, Cadnapaphornchai MA, Chapman AB, Cornec-Le Gall E, Drenth JPH, Gansevoort RT, Harris PC , Harris T et al (2025) . Kidney International, 107(2), 234-254.
Devuyst O, Ahn C, Barten TRM, Brosnahan G, Cadnapaphornchai MA, Chapman AB, Cornec-Le Gall E, Drenth JPH, Gansevoort RT, Harris PC , Harris T et al (2025) . Kidney International, 107(2), S1-S239.
Zagorec N, Calamel A, Delaporte M, Olinger E, Orr S, Sayer JA, Pillay V-G, Denommé-Pichon AS, Mau-Them FT, Nambot S , Faivre L et al (2024) . American Journal of Kidney Diseases.
Harnan S, Gittus M, Falzon L, Durkie M, Mandrik L, Ong AC & Fotheringham J (2024) . Value in Health, 27(12), S493-S493.
Zagorec N, Calamel A, Ars E, Ong A, Halbritter J, Audrezet M-P, Pillay V-G, Le Meur Y, Sayer J & Cornec-Le Gall E (2024) Clinical spectrum and prognosis of the atypical polycystic kidney disease caused by monoallelic loss-of-function IFT140 variants. NEPHROLOGY DIALYSIS TRANSPLANTATION, 39, I213-I214.
Ong A, Valluru M, Streets A & Smith D (2024) . Nephrology Dialysis Transplantation, 39(Supplement_1).
Francis A, Harhay MN, Ong ACM, Tummalapalli SL, Ortiz A, Fogo AB, Fliser D, Roy-Chaudhury P, Fontana M, Nangaku M , Wanner C et al (2024) . Nature Reviews Nephrology, 1-13.
Wong K, Pitcher D, Braddon F, Downward L, Steenkamp R, Annear N, Barratt J, Bingham C, Chrysochou C, Coward RJ , Game D et al (2024) . The Lancet, S0140-6736(23)02843.
Ali H, Malik MZ, Abu‐Farha M, Abubaker J, Cherian P, Nizam R, Jacob S, Bahbahani Y, Naim M, Ahmad S , Al‐Sayegh M et al (2024) . The Journal of Gene Medicine, 26(2), e3674.
Chen EWC, Chong J, Valluru MK, Durkie M, Simms RJ, Harris PC & Ong ACM (2024) . Nephrology Dialysis Transplantation.
Gittus M, Moore J & Ong ACM (2024) . PLOS ONE, 19(1).
Taylor J, Thomas R, Metherall P, van Gastel M, Cornec-Le Gall E, Caroli A, Furlano M, Demoulin N, Devuyst O, Winterbottom J , Torra R et al (2024) . Kidney International Reports.
Wong K, Pitcher D, Braddon F, Downward L, Steenkamp R, Masoud S, Annear N, Barratt J, Bingham C, Coward RJ , Chrysochou T et al (2024) . Kidney International Reports.
Taylor J, Thomas R, Metherall P, van Gastel M, Cornec-Le Gall E, Caroli A, Furlano M, Demoulin N, Devuyst O, Winterbottom J , Torra R et al (2023) . Kidney International Reports.
Lambert K, Gardos R, Coolican H, Pickel L, Sung H-K, Wang AY-M & Ong ACM (2023) . Seminars in Nephrology, 43(2), 151405-151405.
Durkie M, Watson CM, Winship P, Hogg A-C, Nyanhete R, Cooley S, Valluru MK, Shaw-Smith C, Bingham C, Gilchrist M , Kenny J et al (2023) . Human Mutation, 2023.
Gittus M, Harris T & Ong ACM (2023) . Advances in Kidney Disease and Health, 30(3), 294-302.
Cadnapaphornchai MA & Ong ACM (2023) . Clinical Kidney Journal.
Harskamp LR, Perez-Gomez MV, Heida JE, Engels GE, van Goor H, van den Heuvel MC, Streets AJ, Ong ACM, Ortiz A, Gansevoort RT , Drenth JPH et al (2023) . Nephrology Dialysis Transplantation.
Fung WWS, Szeto CC, Chow KM, Cheng P, Kwong V, Lau S, Pang WF, Chu W, Ong A, Devuyst O & Li P (2023) . Kidney International Reports, 8(3), S244-S245.
Perrone RD, Oberdhan D, Ouyang J, Bichet DG, Budde K, Chapman AB, Gitomer BY, Horie S, Ong ACM, Torres VE , Turner AN et al (2023) . Kidney International Reports, 8(5), 989-1001.
Ortiz A, Wanner C, Gansevoort R, Cozzolino M, Fliser D, Ong A, Gambaro G, Rosenkranz AR, Rychlık I, Sarafidis P , Torra R et al (2023) . Nephrology Dialysis Transplantation, 38(3), 527-531.
Ortiz A, Wanner C, Gansevoort R, Cozzolino M, Fliser D, Ong A, Gambaro G, Rosenkranz AR, Rychlık I, Sarafidis P , Torra R et al (2023) . Clinical Kidney Journal, 16(3), 403-407.
Gansevoort RT, Hariri A, Minini P, Ahn C, Chapman AB, Horie S, Knebelmann B, Mrug M, Ong ACM, Pei YPC , Torres VE et al (2022) . American Journal of Kidney Diseases.
Ortiz A, Wanner C, Gansevoort R, Ortiz A, Wanner C, Gansevoort RT, Cozzolino M, Fliser D, Gambaro G, Ong A , Rosenkranz AR et al (2022) . European Journal of Preventive Cardiology.
Valluru MK, Chung NKX, Gilchrist M, Butland L, Cook J, Takou A, Dixit A, Weedon MN & Ong ACM (2022) . Journal of Medical Genetics.
Perrone RD, Hariri A, Minini P, Ahn C, Chapman AB, Horie S, Knebelmann B, Mrug M, Ong ACM, Pei YPC , Torres VE et al (2022) . Kidney Medicine.
Gittus M, Moore J & Ong A (2022) . Journal of Hepatology, 77, S814-S814.
Wanner C (2022) . Clinical Kidney Journal, 15(8), 1439-1446.
Harris T, Bridges HR, Brown WD, O’Brien NL, Daly AC, Jindal BK, Mundy GS, Ong A, Power AJ, Sandford RN , Sayer J et al (2022) . BMJ Open, 12(6).
Winterbottom J, Simms RJ, Caroli A, Gall EC-L, Demoulin N, Furlano M, Meijer E, Devuyst O, Gansevoort RT, Le-Meur Y , Perico N et al (2022) . Clinical Kidney Journal.
Müller R-U, Lianne Messchendorp A, Birn H, Capasso G, Cornec-Le Gall E, Devuyst O, Eerde AV, Guirchoun P, Harris T, Hoorn EJ , Knoers NVAM et al (2022) . Kidneys, 11(1), 37-39.
Cong Eugene Chen W, Ong A & Gittus M (2022) . Nephrology Dialysis Transplantation, 37(Supplement_3).
Kai Xin Chung N, Valluru M, Butland L, Cook J, Dixit A & Ong A (2022) . Nephrology Dialysis Transplantation, 37(Supplement_3).
Ong ACM & Torra R (2022) . Clinical Kidney Journal, 15(6), 1034-1036.
Wanner C, Fliser D, Rychlik I, Torra R, Gansevoort R, Ortiz A, Sarafidis P, Ong A, Cozzolino M, Rosenkranz A , Tuglular SZ et al (2022) . Nephrology Dialysis Transplantation.
Chung NKX, Metherall P, McCormick JA, Simms RJ & Ong ACM (2022) . Clinical Kidney Journal.
Chang M-Y, Tsai T-I, Chou L-F, Hsu S-H, Yang H-Y, Hung C-C, Tian Y-C, Ong ACM & Yang C-W (2021) . Human Molecular Genetics.
Senum SR, Li YSM, Benson KA, Joli G, Olinger E, Lavu S, Madsen CD, Gregory AV, Neatu R, Kline TL , Audrézet M-P et al (2021) . The American Journal of Human Genetics.
Ong ACM & Gansevoort RT (2021) . Kidney International, 100(3), 513-515.
Li D, Hu M, Chen H, Wu X, Wei X, Lin H, Gao X, Wang H, Li M, Ong ACM , Yue Z et al (2021) . Human Molecular Genetics.
Mao Z, Valluru MK & Ong ACM (2021) . Clinical Kidney Journal.
Zhou S, Xu J, Xue C, Yang B, Mao Z & Ong ACM (2021) . Renal Failure, 43(1), 1-15.
Fragiadaki M, Macleod FM & Ong ACM (2020) . International Journal of Molecular Sciences, 21(23).
Durkie M, Chong J, Valluru MK, Harris PC & Ong ACM (2020) . Genetics in Medicine.
Logeman C, Cho Y, Sautenet B, Rangan GK, Gutman T, Craig J, Ong A, Chapman A, Ahn C, Coolican H , Tze-Wah Kao J et al (2020) . BMJ Open, 10(10).
Perrone RD, Hariri A, Minini P, Chapman AB, Horie S, Knebelmann B, Mrug M, Ong AC, Pei YP, Torres VE , Modur V et al (2020) . Journal of the American Society of Nephrology, 31(10S), 502-502.
Perrone RD, Hariri A, Minini P, Ahn C, Chapman AB, Horie S, Knebelmann B, Mrug M, Ong AC, Pei YP , Torres VE et al (2020) . Journal of the American Society of Nephrology, 31(10S), 502-502.
Streets AJ, Prosseda PP & Ong ACM (2020) . JCI Insight, 5(16).
Cho Y, Tong A, Craig JC, Mustafa RA, Chapman A, Perrone RD, Ahn C, Fowler K, Torres V, Gansevoort RT , Ong ACM et al (2020) . American Journal of Kidney Diseases.
Streets A & Ong A (2020) . Cellular Signalling, 72.
Živná M, Kidd K, Zaidan M, Vyleťal P, Barešová V, Hodaňová K, Sovová J, Hartmannová H, Votruba M, Trešlová H , Jedličková I et al (2020) . Kidney International.
Magayr TA, Song X, Streets AJ, Vergoz L, Chang L, Valluru MK, Yap HL, Lannoy M, Haghighi A, Simms RJ , Tam FWK et al (2020) . Kidney International, 98(2), 420-435.
Lannoy M, Valluru MK, Chang L, Abdela-Ali F, Peters DJM, Streets AJ & Ong ACM (2020) . Kidney International, 98(2), 404-419.
Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E , Maimaris J et al (2020) . Nature, 584(7819), E2-E2.
Torres VE & Ong ACM (2020) . Cellular Signalling, 71.
Winterbottom J, Simms R & Ong A (2020) . Nephrology Dialysis Transplantation, 35(Supplement_3).
Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E , Maimaris J et al (2020) . Nature.
Cho Y, Rangan G, Logeman C, Ryu H, Sautenet B, Perrone RD, Nadeau-Fredette A-C, Mustafa RA, Htay H, Chonchol M , Harris T et al (2020) . American Journal of Kidney Diseases.
Huynh VT, Audrézet M-P, Sayer JA, Ong AC, Lefevre S, Le Brun V, Després A, Senum SR, Chebib F, Barroso-Gil M , Patel C et al (2020) . Kidney International.
Sautenet B, Cho Y, Gutman T, Rangan G, Ong A, Chapman AB, Ahn C, Coolican H, Tze-Wah Kao J, Fowler K , Gansevoort RT et al (2020) . American Journal of Kidney Diseases.
Griffiths J, Mills MT & Ong ACM (2020) . BMJ Open, 10(1).
Metzner A, Griffiths JD, Streets AJ, Markham E, Philippou T, Van Eeden FJM & Ong ACM (2020) . Scientific Reports, 10(1).
Hopp K, Cornec-Le Gall E, Senum SR, te Paske IBAW, Raj S, Lavu S, Baheti S, Edwards ME, Madsen CD, Heyer CM , Ong ACM et al (2020) . Kidney International, 97(2), 370-382.
Annear NMP, Appleton RE, Bassi Z, Bhatt R, Bolton PF, Crawford P, Crowe A, Tossi M, Elmslie F, Finlay E , Gale DP et al (2019) . Frontiers in Neurology, 10.
LOGEMAN C, Cho YJ, Sautenet B, Rangan G, Talia G, Johnathan C, Ong A, Arlene C, Curie A & Helen C (2019) . Kidney International Reports, 4(7), S48-S48.
Durkie M, Chong J & Ong A (2019) . Kidney International Reports, 4(7), S148-S148.
Omar F, Findlay JE, Carfray G, Allcock RW, Jiang Z, Moore C, Muir AL, Lannoy M, Fertig BA, Mai D , Day JP et al (2019) . Proceedings of the National Academy of Sciences, 116(27), 13320-13329.
Tam FWK & Ong ACM (2019) . Nephrology,Dialysis and Transplantation.
Simms RJ, Doshi T, Metherall P, Ryan D, Wright P, Gruel N, van Gastel MDA, Gansevoort RT, Tindale W & Ong ACM (2019) . European Radiology, 1-10.
Cho Y, Sautenet B, Gutman T, Rangan G, Craig JC, Ong AC, Chapman A, Ahn C, Coolican H, Kao JTW , Gansevoort R et al (2019) . Nephrology.
Gimpel C, Avni EF, Breysem L, Burgmaier K, Caroli A, Cetiner M, Haffner D, Hartung EA, Franke D, König J , Liebau MC et al (2019) . Radiology.
Tong A, Manns B, Wang AYM, Hemmelgarn B, Wheeler DC, Gill J, Tugwell P, Pecoits-Filho R, Crowe S, Harris T , Van Biesen W et al (2018) . Kidney International, 94(6), 1053-1068.
Selby NM, Blankestijn PJ, Boor P, Combe C, Eckardt K, Eikefjord E, Garcia-Fernandez N, Golay X, Gordon I, Grenier N , Hockings PD et al (2018) . Nephrology Dialysis Transplantation, 33(Sup 2), ii4-ii14.
Harris T, Sandford R, De Coninck B, Devuyst O, Drenth JPH, Ecder T, Kent A, Gansevoort RT, Górriz JL, Ong ACM , Pirson Y et al (2018) . Nephrology Dialysis Transplantation, 33(4), 563-573.
Neagu M, Coca D & Ong ACM (2018) . Am J Kidney Dis.
McEwan P, Bennett Wilton H, Ong ACM, Ørskov B, Sandford R, Scolari F, Cabrera M-CV, Walz G, O’Reilly K & Robinson P (2018) . BMC Nephrology, 19(1).
Ong ACM (2018) . Nature Reviews Nephrology, 14(3), 146-148.
Chang M-Y & Ong ACM (2017) . Nephrology Dialysis Transplantation, 32(12), 2144-2144.
Cho Y, Sautenet B, Rangan G, Craig JC, Ong ACM, Chapman A, Ahn C, Chen D, Coolican H, Kao JT-W , Gansevoort R et al (2017) . Trials, 18(1).
Feng S, Streets AJ, Nesin V, Tran U, Nie H, Onopiuk M, Wessely O, Tsiokas L & Ong A (2017) . Journal of the American Society of Nephrology, 28(10), 2973-2984.
Chang M-Y & C.M. Ong A (2017) . Nephrology Dialysis Transplantation.
Ong ACM (2017) . The Lancet, 389(10081), 1780-1782.
Chong J, Durkie M, Dalton A & Ong A (2017) . Nephrology Dialysis Transplantation, 32(suppl_3), iii94-iii94.
Streets AJ, Magayr TA, Huang L, Vergoz L, Rossetti S, Simms RJ, Harris PC, Peters DJM & Ong ACM (2017) . American Journal of Physiology - Renal Physiology, 312(4), F577-F588.
Fragiadaki M, Lannoy M, Themanns M, Maurer B, Leonhard WN, Peters DJM, Moriggl R & Ong ACM (2017) . Kidney International, 91(3), 575-586.
Simms R, Ryan D, Metherall P, Wright P, Gruel N, Tindale W & Ong A (2017) . The Lancet, 389, S90-S90.
Mao Z, Chong J & Ong ACM (2016) . F1000Research, 5, 2029-2029.
Lannoy M, Abdela-ali F, Streets AJ & Ong ACM (2016) . Nephrology Dialysis Transplantation, 31(suppl_1), i22-i23.
Xu Y, Streets AJ, Hounslow AM, Tran U, Jean-Alphonse F, Needham AJ, Vilardaga J-P, Wessely O, Williamson MP & Ong ACM (2016) . Journal of the American Society of Nephrology, 27(4), 1159-1173.
Gansevoort RT, Arici M, Benzing T, Birn H, Capasso G, Covic A, Devuyst O, Drechsler C, Eckardt K-U, Emma F , Knebelmann B et al (2016) . Nephrology Dialysis Transplantation, 31(3), 337-348.
Simms RJ, Thong KM, Dworschak GC & Ong ACM (2016) . Nephrology Dialysis Transplantation, 31(7), 1130-1140.
Yang B, Chen S, Yang G, Mei C, Ong A & Mao Z (2015) . BMJ Open, 5(11).
Ong ACM & Harris PC (2015) . Kidney International, 88(4), 699-710.
Cantero MDR, Velázquez IF, Streets AJ, Ong ACM & Cantiello HF (2015) . Journal of Biological Chemistry, 290(39), 23888-23896.
Chapman AB, Devuyst O, Eckardt K-U, Gansevoort RT, Harris T, Horie S, Kasiske BL, Odland D, Pei Y, Perrone RD , Pirson Y et al (2015) . Kidney International, 88(1), 17-27.
(2015) . The Lancet, 385(9987), 2576-2576.
Simms RJ, Thong KM, Dworschak GC & Ong ACM (2015) . Nephrology Dialysis Transplantation, 30(suppl_3), iii190-iii190.
Ong ACM, Devuyst O, Knebelmann B & Walz G (2015) . The Lancet, 385(9981), 1993-2002.
Xu Y, Ong ACM, Williamson MP & Hounslow AM (2015) . Biomolecular NMR Assignments, 9(2), 369-373.
Streets AJ, Xu Y & Ong ACM (2015) . Nephrology Dialysis Transplantation, 30(suppl_3), iii63-iii63.
Mao Z, Xie G & Ong ACM (2015) . Nephrology Dialysis Transplantation, 30(2), 197-203.
Ong ACM, von Websky K & Hocher B (2015) . Seminars in Nephrology, 35(2), 197-207.
Simms RJ, Travis DL, Durkie M, Wilson G, Dalton A & Ong ACM (2015) . Transplantation, 99(5), 1023-1029.
McEwan P, Bennett Wilton H, Robinson P, Hadimeri H, Ong A, Ørskov B, Peces R, Sandford R, Scolari F, Walz G , Woon C et al (2014) . Value in Health, 17(7), A564-A564.
Petzold K, Gansevoort RT, Ong ACM, Devuyst O, Rotar L, Eckardt K-U, Köttgen A, Pirson Y, Remuzzi G, Sandford R , Tesar V et al (2014) . Nephrology Dialysis Transplantation, 29(suppl_4), iv26-iv32.
Thong KM & Ong ACM (2014) . Nephrology Dialysis Transplantation, 29(suppl 4), iv121-iv123.
Simms RJ & Ong ACM (2014) . Nephrology Dialysis Transplantation, 29(suppl 4), iv106-iv112.
Devuyst O, Knoers NVAM, Remuzzi G & Schaefer F (2014) . The Lancet, 383(9931), 1844-1859.
Cabrera-López C, Ars E, Marti T, Harris PC, Torra R, Clerckx C, Migeon T, Chen Z, Ronco P, Plaisier E , Lamers IJ et al (2014) . Nephrol Dial Transplant, 29 Suppl 3, iii73-iii78.
Alfieri A, Ong ACM, Kammerer RA, Solanky T, Bate S, Tasab M, Brown NJ & Brookes ZL (2014) . Pharmacol Res, 80, 43-51.
(2014) . Nephrology Dialysis Transplantation, 29(12), 2353-2353.
Spithoven EM, Kramer A, Meijer E, Orskov B, Wanner C, Abad JM, Areste N, Alonso de la Torre R, Caskey F, Couchoud C , Finne P et al (2014) . Nephrology Dialysis Transplantation, 29(suppl 4), iv15-iv25.
Spithoven EM, Kramer A, Meijer E, Orskov B, Wanner C, Caskey F, Collart F, Finne P, Fogarty DG, Groothoff JW , Hoitsma A et al (2014) . Kidney International, 86(6), 1244-1252.
Lin L, Xu Y, Zhang S, Ross IM, Ong ACM & Allwood DA (2014) . Small, 10(1), 60-65.
Chang MY & Ong ACM (2013) . British Journal of Clinical Pharmacology, 76(4), 524-535.
Thong KM, Xu Y, Cook J, Takou A, Wagner B, Kawar B & Ong ACM (2013) . Nephron Clin Pract, 124(1-2), 31-37.
Lin L, Xu Y, Zhang S, Ross IM, Ong ACM & Allwood DA (2013) . ACS Nano, 7(9), 8214-8223.
Liu Y, Käch A, Ziegler U, Ong ACM, Wallace DP, Arcaro A & Serra AL (2013) . PLoS ONE, 8(8).
Ong ACM (2013) . Nephrol Dial Transplant, 28(11), 2661-2663.
Thong KM & Ong ACM (2013) . QJM, 106(7), 639-646.
Streets AJ, Wessely O, Peters DJM & Ong ACM (2013) . Hum Mol Genet, 22(10), 1924-1939.
Mekahli D, Decuypere J-P, Sammels E, Welkenhuyzen K, Bultynck G, Parys JB, Missiaen L, De Smedt H, Levtchenko E, Schoeber J , van den Heuvel L et al (2013) . Pflugers Archiv European Journal of Physiology, 1-14.
Brookes ZLS, Ruff L, Upadhyay VS, Huang L, Prasad S, Solanky T, Nauli SM & Ong ACM (2013) . Am J Physiol Heart Circ Physiol, 304(1), H33-H41.
Loftus H & Ong ACM (2013) . Pediatr Nephrol, 28(1), 33-49.
Devuyst O, Antignac C, Bindels RJM, Chauveau D, Emma F, Gansevoort R, Maxwell PH, Ong ACM, Remuzzi G, Ronco P & Schaefer F (2012) . Nephrology Dialysis Transplantation, 27(1), 67-69.
Chang M-Y & Ong ACM (2012) . NEPHRON CLINICAL PRACTICE, 120(1), C25-C34.
Mao Z & Ong ACM (2012) . QJM, 105(7), 693-696.
Mekahli D, Sammels E, Decuypere JP, Audrezet MP, Dechenes G, Ong A, van den Heuvel L, Missiaen L, De Smedt H & Levtchenko E (2011) mTOR signaling is differentially affected in human renal cells with PKD1 or PKD2 mutations. PEDIATR NEPHROL, 26(9), 1648-1648.
Chang M-Y & Ong ACM (2011) . Contrib Nephrol, 172, 200-209.
Feng S, Rodat-Despoix L, Delmas P & Ong ACM (2011) . J Biol Chem, 286(21), 18994-19000.
Mao Z, Streets AJ & Ong ACM (2011) . Am J Physiol Renal Physiol, 300(6), F1375-F1384.
Ong ACM & Devuyst O (2011) . NEPHRON CLIN PRACT, 118(1), C3-C8.
Ong ACM & Gubler MC (2011) . Medicine, 39(2), 119-125.
Streets AJ, Needham AJ, Gill SK & Ong ACM (2010) . Mol Biol Cell, 21(22), 3853-3865.
Giamarchi A, Feng S, Rodat-Despoix L, Xu YX, Bubenshchikova E, Newby LJ, Hao JZ, Gaudioso C, Crest M, Lupas AN , Honore E et al (2010) . EMBO J, 29(7), 1176-1191.
Yu Y, Ulbrich MH, Li M-H, Buraei Z, Chen X-Z, Ong ACM, Tong L, Isacoff EY & Yang J (2010) . Biophysical Journal, 98(3), 344a-344a.
Yu Y, Ulbrich MH, Li M-H, Buraei Z, Chen X-Z, Ong ACM, Tong L, Isacoff EY & Yang J (2010) Structural and Molecular Basis of the Assembly of the TRPP2/PKD1 Complex. BIOPHYSICAL JOURNAL, 98(3), 343A-343A.
(2009) . BMJ, 339(oct13 2), b4204-b4204.
Prasad S, McDaid JP, Tam FWK, Haylor JL & Ong ACM (2009) . Am J Pathol, 175(4), 1493-1503.
Ong ACM (2009) . BMJ, 339, b3763.
Laycock S, Taylor HC, Haigh C, Lee AT, Cooper GJ, Ong ACM & Robson L (2009) . Exp Physiol, 94(8), 914-927.
Chow CL & Ong ACM (2009) . Clin Med (Lond), 9(3), 278-283.
Streets AJ, Wagner BE, Harris PC, Ward CJ & Ong ACM (2009) . J Cell Sci, 122(Pt 9), 1410-1417.
Mao Z & Ong ACM (2009) . Nephron Clin Pract, 112(4), c230-c241.
Streets AJ, Wagner BE, Harris PC, Ward CJ & Ong ACM (2009) . Journal of Cell Science, 122(10), 1702.
Yu Y, Ulbrich MH, Li MH, Buraei Z, Chen XZ, Ong ACM, Tong L, Isacoff EY & Yang J (2009) . Proceedings of the National Academy of Sciences of the United States of America, 106(28), 11558-11563.
Feng S, Okenka GM, Bai C-X, Streets AJ, Newby LJ, DeChant BT, Tsiokas L, Obara T & Ong ACM (2008) . J Biol Chem, 283(42), 28471-28479.
Bai CX, Kim S, Li WP, Streets AJ, Ong AC & Tsiokas L (2008) . EMBO J, 27(9), 1345-1356.
Chang M-Y & Ong ACM (2008) . Nephron Physiol, 108(1), p1-p7.
Parker E, Newby LJ, Sharpe CC, Rossetti S, Streets AJ, Harris PC, O'Hare MJ & Ong ACM (2007) . Kidney Int, 72(2), 157-165.
Chang M-Y, Parker E, El Nahas M, Haylor JL & Ong ACM (2007) . J Am Soc Nephrol, 18(2), 560-569.
Hamer RA, Chow CL, Ong ACM & McKane WS (2007) . Transplantation, 83(1), 36-40.
Bernhardt WM, Wiesener MS, Weidemann A, Schmitt R, Weichert W, Lechler P, Campean V, Ong ACM, Willam C, Gretz N & Eckardt KU (2007) . American Journal of Pathology, 170(3), 830-842.
Ali A, Christie PT, Grigorieva IV, Harding B, Van Esch H, Ahmed SF, Bitner-Glindzicz M, Blind E, Bloch C, Christin P , Clayton P et al (2007) . Human Molecular Genetics, 16(3), 265-275.
Chang MY, Parker E, Ibrahim S, Shortland JR, Nahas ME, Haylor JL & Ong ACM (2006) . Nephrol Dial Transplant, 21(8), 2078-2084.
Streets AJ, Moon DJ, Kane ME, Obara T & Ong ACM (2006) . Hum Mol Genet, 15(9), 1465-1473.
Ong ACM & Wagner B (2005) . Am J Kidney Dis, 45(6), 1096-1099.
Ong ACM & Harris PC (2005) . Kidney Int, 67(4), 1234-1247.
Le NH, van der Bent P, Huls G, van de Wetering M, Loghman-Adham M, Ong ACM, Calvet JP, Clevers H, Breuning MH, van Dam H & Peters DJM (2004) . J BIOL CHEM, 279(26), 27472-27481.
Streets AJ, Newby LJ, O'Hare MJ, Bukanov NO, Ibraghimov-Beskrovnaya O & Ong ACM (2003) . J Am Soc Nephrol, 14(7), 1804-1815.
Ong ACM (2003) . Medicine, 31(5), 32-35.
Ong ACM & Wheatley DN (2003) . Lancet, 361(9359), 774-776.
Rossetti S, Chauveau D, Kubly V, Slezak JM, Saggar-Malik AK, Pei Y, Ong ACM, Stewart F, Watson ML, Bergstralh EJ , Winearls CG et al (2003) . Lancet, 361(9376), 2196-2201.
Ong ACM, Newby LJ & Dashwood MR (2003) . Nephron Exp Nephrol, 93(2), e80.
Zhao Y, Haylor JL & Ong ACM (2002) . Nephrol Dial Transplant, 17(12), 2138-2144.
Harris P, Rossetti S, Chauveau D, Kubly V, Bergstralh E, Slezak J, Ong A, Sagger-Malik A, Pei Y, Winearls C & Torres V (2002) Genotype/phenotype correlations in ADPKD: Vascular complications.. J AM SOC NEPHROL, 13, 40A-40A.
Streets AJ, Ibraghimov-Beskrovnaya O & Ong ACM (2002) Polycystin-1 mediates cell-cell adhesion in PKD1 transgenic and non-transgenic lines. J AM SOC NEPHROL, 13, 46A-46A.
Newby LJ, Streets AJ, Zhao Y, Harris PC, Ward CJ & Ong ACM (2002) . J Biol Chem, 277(23), 20763-20773.
Ong ACM (2000) Polycystin expression in the kidney and other tissues: Complexity, consensus and controversy. EXP NEPHROL, 8(4-5), 208-214.
Ong AC (2000) . Exp Nephrol, 8(4-5), 208-214.
Benigni A, Madias NE, Remuzzi G, Siragy HM, Brooks DP, Rossi GP, Abbate M, Ong A, Loeffler BM, Bender N , Noris M et al (2000) Endothelin antagonists in renal disease. KIDNEY INT, 57(4), 1778-1794.
Ong ACM, Harris PC, Rossetti S, Davies DR & Ward CJ (1999) Polycystin expression in PKD-1, infantile PKD-1 and TSC-2/PKD-1 cystic tissue: heterogenous expression of the normal allele in cystic epithelia.. KIDNEY INT, 55(6), 2559-2559.
Ong AC, Harris PC, Biddolph S, Bowker C & Ward CJ (1999) . Kidney Int, 55(5), 2091-2116.
Ong ACM, Harris PC, Biddolph S, Bowker C & Ward CJ (1999) Characterisation and expression of the PKD-1 protein, polycystin, in renal and extrarenal tissues.. KIDNEY INT, 55(5), 2091-2091.
Ong ACM, Mole DR & Altmann P (1999) An unusual complication of pregnancy. NEPHROL DIAL TRANSPL, 14(5), 1324-1326.
Ong AC, Mole DR & Altmann P (1999) . Nephrol Dial Transplant, 14(5), 1324-1326.
Ong ACM (1999) Cyst formation in ADPKD: new insights from natural and targeted mutants. NEPHROL DIAL TRANSPL, 14(3), 544-546.
Ong AC (1999) . Nephrol Dial Transplant, 14(3), 544-546.
Ong AC, Ward CJ, Butler RJ, Biddolph S, Bowker C, Torra R, Pei Y & Harris PC (1999) . Am J Pathol, 154(6), 1721-1729.
Ong AC, Harris PC, Davies DR, Pritchard L, Rossetti S, Biddolph S, Vaux DJ, Migone N & Ward CJ (1999) . Kidney Int, 56(4), 1324-1333.
Dashwood MR, Timm M, Muddle JR, Ong AC, Tippins JR, Parker R, McManus D, Murday AJ, Madden BP & Kaski JC (1998) . Endothelium, 6(1), 61-70.
Ong ACM, Harris PC, Biddolph S, Bowker C & Ward CJ (1997) Characterisation, cellular expression, tissue localisation and developmental modulation of the PKD-1 product, polycystin.. J AM SOC NEPHROL, 8, A1744-A1744.
Ong ACM, Ward CJ, Biddolph S, Migone N & Harris PC (1997) Polycystin expression in PKD-1, infantile PKD-1 and TSC-2/PKD-1 cystic kidney: Evidence against a two-hit disease mechanism in cyst initiation.. J AM SOC NEPHROL, 8, A1745-A1745.
Peral B, Gamble V, Strong C, Ong AC, Sloane-Stanley J, Zerres K, Winearls CG & Harris PC (1997) . Am J Hum Genet, 60(6), 1399-1410.
Ong AC & Harris PC (1997) . Lancet, 349(9058), 1039-1040.
Ong AC (1997) Renal disease. II. The polycystic kidney disease 1 (PKD-1) gene: an important clue in the study of renal cyst formation.. J R Coll Physicians Lond, 31(2), 141-146.
Ong ACM (1997) The polycystic kidney disease 1 (PKD-1) gene: An important clue in the study of renal cyst formation. Journal of the Royal College of Physicians of London, 31(2), 141-146.
Peral B, Gamble V, Ong ACM, SanMillan JL & Harris PC (1996) Mutation defection in polycystic kidney disease 1 (PKD1) gene.. J AM SOC NEPHROL, 7(9), A1856-A1856.
Peral B, Ong AC, San Millán JL, Gamble V, Rees L & Harris PC (1996) . Hum Mol Genet, 5(4), 539-542.
Ward CJ, Turley H, Ong AC, Comley M, Biddolph S, Chetty R, Ratcliffe PJ, Gattner K & Harris PC (1996) . Proc Natl Acad Sci U S A, 93(4), 1524-1528.
Rowe PS, Ong AC, Cockerill FJ, Goulding JN & Hewison M (1996) . Bone, 18(2), 159-169.
Ong AC (1996) . Nephrol Dial Transplant, 11(2), 251-257.
Ong ACM (1996) Surprising new roles for endothelins - Mutant mice reveal the first clear links to human disease. BRIT MED J, 312(7025), 195-196.
Ong AC (1996) . BMJ, 312(7025), 195-196.
Peral B, SanMillan JL, Ong ACM, Gamble V, Ward CJ, Strong C & Harris PC (1996) Screening the 3' region of the polycystic kidney disease 1 (PKD1) gene reveals six novel mutations. AM J HUM GENET, 58(1), 86-96.
Ong ACM (1996) Surprising new roles for endothelins - Mutant mice reveal the first clear links to human disease. British Medical Journal, 312(7025), 195-196.
Peral B, San Millán JL, Ong AC, Gamble V, Ward CJ, Strong C & Harris PC (1996) Screening the 3' region of the polycystic kidney disease 1 (PKD1) gene reveals six novel mutations.. Am J Hum Genet, 58(1), 86-96.
WARD CJ, TURLEY H, ONG ACM, GATTER KC & HARRIS PC (1995) CHARACTERIZATION OF THE POLYCYSTIC-KIDNEY-DISEASE-1 (PKD1) PROTEIN, POLYCYSTIN. J AM SOC NEPHROL, 6(3), 713-713.
ONG ACM (1995) ENDOTHELIN DEPENDENT AND INDEPENDENT GROWTH SYSTEMS INVOLVED IN HUMAN PROXIMAL TUBULAR AUTOREGENERATION. J AM SOC NEPHROL, 6(3), 773-773.
Ong AC, Jowett TP, Firth JD, Burton S, Karet FE & Fine LG (1995) . Kidney Int, 48(2), 390-401.
Rowe PSN, Hewison M, Cockerill FJ, Goulding JN, Ong A & O'Riordan JLH (1995) . Bone, 16(6), 679-679.
ONG ACM, FIRTH ID, IOWETT TP, BURTON S, KARET FE & FINE LG (1995) A HYPOXIA-INDUCIBLE, ENDOTHELIN-1 MEDIATED, AUTOCRINE GROWTH LOOP INVOLVED IN HUMAN RENAL TUBULAR REGENERATION. KIDNEY INT, 47(2), 693-693.
Fine LG, Norman JT & Ong A (1995) Cell-cell cross-talk in the pathogenesis of renal interstitial fibrosis. Kidney International, Supplement(49).
Ong AC, Jowett TP, Moorhead JF & Owen JS (1994) . Kidney Int, 46(5), 1315-1321.
ONG ACM, FIRTH JD, JOWETT TP, BURTON S, KARET FE & FINE LG (1994) AUTOREGENERATION OF HUMAN PROXIMAL TUBULAR CELLS MEDIATED BY A HYPOXIA-INDUCIBLE ENDOTHELIN-1 (ET-1) GROWTH LOOP. J AM SOC NEPHROL, 5(3), 699-699.
ONG ACM, JOWETT TP, FIRTH JD, BURTON S, KITAMURA M & FINE LG (1994) HUMAN TUBULAR-DERIVED ENDOTHELIN IN THE PARACRINE REGULATION OF RENAL INTERSTITIAL FIBROBLAST FUNCTION. EXP NEPHROL, 2(2), 134-134.
Ong AC & Moorhead JF (1994) . Kidney Int, 45(3), 753-762.
Ong AC, Jowett TP, Firth JD, Burton S, Kitamura M & Fine LG (1994) Human tubular-derived endothelin in the paracrine regulation of renal interstitial fibroblast function.. Exp Nephrol, 2(2), 134.
Ong AC & Fine LG (1994) . Kidney Int, 45(2), 345-351.
Ong AC & Fine LG (1994) . Am J Kidney Dis, 23(2), 205-209.
Ong AC & Fine LG (1994) . Nephrol Dial Transplant, 9(5), 471-472.
Fine LG, Ong AC & Norman JT (1993) . Eur J Clin Invest, 23(5), 259-265.
Ong AC, Jowett TP, Scoble JE, O'Shea JA, Varghese Z & Moorhead JF (1993) . Nephrol Dial Transplant, 8(8), 748-753.
MACKIE ADR, SCOBLE J, ONG A, MILLWARD BA & DEMAINE AG (1992) ISOLATION OF THE NA+/H+ ANTIPORTER GENE EXPRESSED IN HUMAN PROXIMAL TUBULE CELLS. DIABETOLOGIA, 35, A56-A56.
ONG ACM, SCOBLE JE, BAILLOD RA, FERNANDO ON, SWENY P & MOORHEAD JF (1992) TUBERCULOUS PERITONITIS COMPLICATING PERITONEAL-DIALYSIS - A CASE FOR EARLY DIAGNOSTIC LAPAROTOMY. NEPHROL DIAL TRANSPL, 7(5), 443-446.
Ong AC, Scoble JE, Baillod RA, Fernando ON, Sweny P & Moorhead JF (1992) Tuberculous peritonitis complicating peritoneal dialysis: a case for early diagnostic laparotomy?. Nephrol Dial Transplant, 7(5), 443-446.
Ong AC & Handler CE (1991) . Int J Cardiol, 30(3), 364-366.
Ong AC, Eisen V, Rennie DP, Homburg R, Lachelin GC, Jacobs HS & Slater JD (1991) . Clin Endocrinol (Oxf), 34(1), 43-49.
TOMLINSON B, ONG ACM, GRAHAM BR & PRICHARD BNC (1990) EFFECTS OF NORADRENALINE INFUSION ON CARDIAC-OUTPUT AND SYSTOLIC-TIME INTERVALS DERIVED FROM ELECTRICAL BIOIMPEDANCE CARDIOGRAPHY. BRIT J CLIN PHARMACO, 29(5), P639-P640.
Ong AC, Handler CE & Slater JD (1990) . Eur Heart J, 11(4), 368-371.
Tomlinson B, Ong ACM, Graham BR & Prichard BNC (1990) Effects of noradrenaline infusion on cardiac output and systolic time intervals derived from electrical bioimpedance cardiography. British Journal of Clinical Pharmacology, 29(5).
Ong AC (1990) . Nephrol Dial Transplant, 5(10), 904-905.
Tomlinson B, Smith CC, Ong AC, Graham BR, Betteridge DJ & Prichard BN (1989) . J Hypertens Suppl, 7(6), S166-S167.
Ong A & Slater JD (1989) . Postgrad Med J, 65(767), 660-661.
Ong AC, Handler CE & Walker JM (1988) . Int J Cardiol, 21(1), 71-73.
Cipriani V, Vestito L, Magavern EF, Jacobsen JOB, Arno G, Behr ER, Benson KA, Bertoli M, Bockenhauer D, Bowl MR , Burley K et al () . Nature, 1-9.
Fung WW-S, Szeto C-C, Chow K-M, Cheng PM-S, Kwong VW-K, Lau SL-F, Pang W-F, Chu WC-W, Ong ACM, Devuyst O & Li PK-T () . Kidney360.
Bais T, Meijer E, Kramers BJ, Vart P, Vervloet M, Salih M, Bammens B, Demoulin N, Todorova P, Müller R-U , Halbritter J et al () . Trials, 25(1).
Brooks EC, Zeidler MP, Ong ACM & Evans IR () . Frontiers in Immunology, 14.
Wang Q, Zou B, Wei X, Lin H, Pang C, Wang L, Zhong J, Chen H, Gao X, Li M , Ong ACM et al () . Frontiers in Cell and Developmental Biology, 11, 1192935.
Gittus M, Chong J, Sutton A, Ong ACM & Fotheringham J () . Orphanet Journal of Rare Diseases, 18(1).
Chong J, Harris T & Ong ACM () . Clinical Kidney Journal.
Müller R-U, Messchendorp AL, Birn H, Capasso G, Cornec-Le Gall E, Devuyst O, van Eerde A, Guirchoun P, Harris T, Hoorn EJ , Knoers NVAM et al () . Nephrology Dialysis Transplantation.
() . Nephrology Dialysis Transplantation.
Patera F, Hautbergue GM, Wilson P, Evans PC, Ong ACM & Fragiadaki M () .

Chapters

Ong ACM & Sandford R (2015) , Oxford Textbook of Clinical Nephrology (pp. 2625-2626). Oxford University Press
Ong ACM & Ellam T (2015) , Oxford Textbook of Clinical Nephrology (pp. 2627-2633). Oxford University Press
Ong ACM & Maxwell AP (2014) , Genomic Medicine (pp. 369-392). Oxford University Press
Streets A & Ong A (2014) , Pathologies of Calcium Channels (pp. 491-522). Springer Berlin Heidelberg
Ong ACM & Maxwell AP (2008) , Genomics and Clinical Medicine (pp. 195-212). Oxford University PressNew York, NY
Lim E, Ali Z, Varty K, Wallwork J, Poole-Wilson P, Lim E, Shahidi M, Polkey M, Goldstraw P, Kanagalingam J , Shaida A et al (2007) , Medicine and Surgery (pp. xi-xii). Elsevier

Conference proceedings papers

Ong A, Valluru M, Streets A & Smith D (2024) A Polycystin-1-Bicaudal C1 complex regulates focal adhesion function through integrin beta-1, F-actin organisation and local translation in HKE cells. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 39 (pp I219-I219)
Harnan S, Gittus M, Falzon L, Durkie M, Mandrik L, Ong AC & Fotheringham J (2024) THE DIAGNOSTIC ACCURACY OF ULTRASOUND AND GENETIC TESTS FOR THE DIAGNOSIS OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE: A SYSTEMATIC MAPPING REVIEW. VALUE IN HEALTH, Vol. 27(12)
Gittus M, Moore J & Ong A (2022) . Abstracts
Gittus M, Moore J & Ong A (2022) Patients with polcystic liver disease have longer waiting times but better clinical outcomes following liver transplantation in the UK. JOURNAL OF HEPATOLOGY, Vol. 77 (pp S814-S814)
Chen WCE, Ong A & Gittus M (2022) THE INTERACTION OF GENDER AND GENOTYPE IN THE DEVELOPMENT OF POLYCYSTIC LIVER DISEASE IN ADPKD. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 37 (pp I7-I7)
Chung NKX, Valluru M, Butland L, Cook J, Dixit A & Ong A (2022) FAMILIAL CLUSTERING OF A RARE UMOD VARIANT IN UNDIAGNOSED HEREDITARY NEPHROPATHY SUGGESTS THE PRESENCE OF A COMMON ANCESTRAL FOUNDER MUTATION. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 37 (pp I14-I15)
Winterbottom J, Simms R, Caroli A, Cornec-Le Gall E, Demoulin N, Furlano M, Meijer E, Devuyst O, Gansevoort R, LeMeur Y , Perico N et al (2021) FLANK PAIN HAS A MAJOR NEGATIVE IMPACT ON HEALTH-RELATED QUALITY OF LIFE IN ADPKD: THE CYSTIC I STUDY. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 36
Winterbottorn J, Simms R & Ong A (2020) REDUCED QUALITY OF LIFE IN ADPKD PATIENTS WITH CKD STAGE 1-3: THE CYSTIC I QUALITY OF LIFE STUDY. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 35 (pp 98-98)
Magayr T, Streets A & Ong A (2020) . Kidney International Reports, Vol. 5(3) (pp S185-S185). Abu Dhabi, United Arab Emirates, 26 March 2020 - 29 March 2020.
Vinh TH, Audrezet M-P, Domenger C, Bridoux F, Seret G, Longuet H, Halimi J-M, Senum S, Pajot A, Albaret J , Ponlot E et al (2019) CLINICAL PRESENTATION AND PROGNOSIS OF DNAJB11-ASSOCIATED NEPHROPATHY: AN INTERNATIONAL COLLABORATIVE STUDY. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 34
Magayr T, Streets A & Ong A (2019) GLOBAL MICRORNA PROFILING IN HUMAN URINARY EXOSOMES REVEALS NEW DISEASE BIOMARKERS AND CELLULAR PATHWAYS FOR AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD). NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 34
Gimpel C, Avni EF, Breysem L, Burgmaier K, Caroli A, Cetiner M, Haffner D, Hartung EA, Franke D, König J , Liebau MC et al (2018) . Ultraschall in der Medizin, 14 November 2018 - 16 November 2018.
Logeman C, Cho Y, Sautenet B, Rangan G, Gutman T, Craig J, Ong ACM, Chapman A, Ahn C, Coolican H , Kao JT-W et al (2018) PATIENT AND CAREGIVER BELIEFS, ATTITUDES AND PERSPECTIVES ON GENETIC SCREENING AND TESTING FOR AUTOSOMAL POLYCYSTIC KIDNEY DISEASE. NEPHROLOGY, Vol. 23 (pp 88-88)
Chong J, Durkie M, Dalton A & Ong A (2017) VERY EARLY-ONSET AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE DUE TO BI-ALLELIC MUTATIONS IN PKD1 AND PKD2. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 32 (pp 94-94)
Simms RJ, Ryan D, Metherall P, Wright P, Gruel N, Tindale W & Ong ACM (2016) . Nephrology Dialysis Transplantation, Vol. 31(suppl_1) (pp i22-i22)
Lannoy M, Abdela-ali F, Streets AJ & Ong ACM (2016) SELECTIVE PROSTAGLANDIN E2 RECEPTOR BLOCKADE FOR THE TREATMENT OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 31 (pp 22-23)
Rocío Cantero MD, Velázquez IF, Streets AJ, Ong ACM & Cantiello HF (2016) . Biophysical Journal, Vol. 110(3) (pp 611a-612a)
Robinson P, McEwan P, Ong ACM, Ørskov B, Sandford R, Scolari F, Walz G, Bennet-Wilton H & O'Reilly K (2015) . Nephrology Dialysis Transplantation, Vol. 30(suppl_3) (pp iii85-iii86)
Simms RJ, Thong KM, Dworschak GC & Ong ACM (2015) INCREASED PSYCHOSOCIAL BURDEN AND ADVERSE QUALITY OF LIFE IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 30
Streets AJ, Xu Y & Ong ACM (2015) . NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 30
Robinson P, McEwan P, Hadimeri H, Ong ACM, Orskov B, Peces R, Sandford R, Scolari F, Walz G, Cooke C & O'Reilly K (2014) DEVELOPMENT OF A MODEL TO PREDICT DISEASE PROGRESSION IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD). NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 29 (pp 75-75)
Holden BJ, van Eeden FJ, Ong ACM & Chico TJ (2011) . HEART, Vol. 97(20) (pp 12-12)
Al-Marwani AO, Pearson D, Wagner B, Ong AC, Makris M & Daly ME (2009) Molecular genetic basis of inherited thrombocytopenia. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 7 (pp 342-342)
Streets AJ, Ibraghimov-Beskrovnaya O & Ong ACM (2003) Regulation of polycystin-1 mediated intercellular adhesion by phosphorylation in renal epithelia cells. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 575A-575A)
Robson L, Laycock SK, Brier T, Ong ACM & Haigh C (2003) A Ca2+-activated conductance in cultured mouse collecting duct cells.. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 80A-80A)
Zhao Y, Haylor JL & Ong ACM (2002) Upregulation of polycystin-2 expression following experimental ischaemic renal injury.. J AM SOC NEPHROL, Vol. 13 (pp 113A-113A)

Preprints

Tran U, Streets AJ, Smith D, Decker E, Kirschfink A, Izem L, Hassey JM, Rutland B, Valluru MK, Bräsen JH , Ott E et al (2024) , Cold Spring Harbor Laboratory.
Cipriani V, Vestito L, Magavern EF, Jacobsen JOB, Arno G, Behr ER, Benson KA, Bertoli M, Bockenhauer D, Bowl MR , Burley K et al (2023) , Cold Spring Harbor Laboratory.
Brooks EC, Zeidler MP, Ong ACM & Evans IR (2023) , Cold Spring Harbor Laboratory.
Gittus MJ, Chong J, Sutton A, Ong A & Fotheringham J () , Research Square Platform LLC.

Research group

Dr Andrew Streets
Dr Manoj Valluru
Dr Rebecca Walker
Dr Joshua Griffiths
Dr Matthew Gittus
Dr Zhu Zhou
Mr Patryk Zarecki
Ms Monica Neilan
Mr Carl Wright

Teaching activities

I have had a long-standing commitment to postgraduate nephrology training especially to develop clinical and non-clinical academics in renal science and in enhancing nephrology training for young nephrologists for the developing ‘two-thirds’ world.

I was appointed Deputy Director for Clinical Academic Training at ��«Ӱҵ (2020-2023), having served as Academic Programme Director for Nephrology (2013-2022). I was a member of the ISN Fellowship Committee (2019-2023), the Scientific Advisory Board of the ERA (2016-2022) and was a member of the UK Renal Association Executive committee as Chair of the International Committee (2009-2013).

Professional activities and memberships

National and International Committees

European Renal Association – Council member
European Renal Association - Scientific Program Chair 61^st ERA Congress 2024
MRC-NIHR Renal Ciliopathies National Network – Co-Director
CYSTic Consortium – Chief investigator
ADPKD in Europe Consortium - Co-chair
European ADPKD Forum – Faculty member

Editorial Boards

Theme Editor, Nephrology Dialysis Transplantation
Faculty of 1000 Medicine, Nephrology faculty

Advisory Boards

Mayo Translational PKD Centre, Mayo Clinic, Rochester - External Faculty
Renal Genomic England Clinical Interpretation Partnership (GeCIP) – Co-chair for Cystic Diseases (2017-2023)
National Institute for Clinical Excellence (NICE) Technology Appraisal of Tolvaptan for ADPKD - Nominated Clinical Expert (2013-2015)

National and International Guidelines

UK Kidney Association Working Group for Tolvaptan in ADPKD – Chair
Kidney Diseases Improving Global Outcomes (KDIGO) ADPKD Guideline Initiative – Working group and Theme lead
Standardised Outcomes in Nephrology–PKD (SONG-PKD) – Steering committee