Heller, Simon, Professor

Professor Simon Heller

Clinical Medicine, School of Medicine and Population Health

Professor of Clinical Diabetes

s.heller@sheffield.ac.uk
+44 114 215 9009

+44 114 215 9004 (For Admin Support, contact Lindsey Crowson)

Room EU38, E Floor, The Medical School

Full contact details

Professor Simon Heller
Clinical Medicine, School of Medicine and Population Health
Room EU38, E Floor
The Medical School
Beech Hill Road
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S10 2RX

Profile: For enquiries please contact - ClinMed-Operational@sheffield.ac.uk

Research interests

Our groups interests concern clinical research, focussing on clinical investigation involving varied topics with the common theme of immediate relevance to patients with diabetes.

These include aspects of the pathophysiology of hypoglycaemia in diabetes, the contribution of hypoglycaemia to the increased risk of sudden death in young people with Type 1 diabetes (the 'dead in bed' syndrome), the clinical benefits of insulin analogues and trials of complex interventions to enable more effective self-management in people with diabetes.

Our observation that hypoglycaemia unawareness is caused by repeated episodes of hypoglycaemia has led to programmes of unawareness reversal and restoration of hypoglycaemic symptoms in patients with Type 1 diabetes.

Recent research on profound bradycardia during hypoglycaemia in patients with type 2 diabetes and ischaemic heart disease has commanded international attention (Chow et al, Diabetes 2014) and a collaboration between the pharmaceutical industry and our research group has led to recently published guidance to advise the FDA and other agencies of important issue when assessing cardiac electrophysical safety of therapeutic agents in diabetes (Heller et al Am Heart J 2015).

We were the principal investigators for the multi-centre DAFNE trial and lead a national programme of research exploring different facets of the DAFNE education programme.

This has directly led to funded roll-out of the approach by the Department of Health, an appraisal by NICE and recent NICE recommendations that training programmes be available to all patients throughout England and Wales. NIHR awarded a ?1.7m 5 year NIHR programme grant, using the DAFNE collaborative (with >30,000 UK trained adults with type 1 diabetes) as a research test-bed.

Following its successful completion (Heller et al, NIHR Journals Lib 2014), the NIHR has recently provided ?2..7m programme funding over 5.5 years to continue this work, which has led to improved diabetes care with national and international impact.

Other research has also explored the potential of technology to improve blood glucose control and reduce hypoglycaemia in diabetes and work with the pharmaceutical industry in evaluating the benefit of new insulins (Heller et al Diabetes Care 1999, Heller et al Lancet 2012) and participated in multi-centre trials evaluating technology (Little et al Diabetes Care 2014) and closed loop devices (Thabit et al Lancet Diabetes Endocrinol 2014). Designed and subsequently led the recently completed REPOSE Trial, a multi-centre.?2m HTA funded RCT conducted in England and Scotland, measuring the effectiveness of insulin pump therapy in adults with type 1 diabetes."

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Fabricius TW, Verhulst CEM, Kristensen PL, Tack CJ, McCrimmon RJ, Heller S, Evans ML, Amiel SA, Pieber TR, de Galan BE & Pedersen-Bjergaard U (2021) . Diabetologia, 64(4), 727-736.
Stanton�\Fay SH, Hamilton K, Chadwick PM, Lorencatto F, Gianfrancesco C, de Zoysa N, Coates E, Cooke D, McBain H, Heller SR & Michie S (2021) . Diabetic Medicine.
Ali Abdelhamid Y, Bernjak A, Phillips LK, Summers MJ, Weinel LM, Lange K, Chow E, Kar P, Horowitz M, Heller S & Deane AM (2021) . Critical Care Medicine, 49(4), 636-649.
Coates E, Amiel S, Baird W, Benaissa M, Brennan A, Campbell M, Chadwick P, Chater T, Choudhary P, Cooke D , Cooper C et al (2021) . BMJ Open, 11(1).
Moser O, Riddell MC, Eckstein ML, Adolfsson P, Rabasa-Lhoret R, van den Boom L, Gillard P, N?rgaard K, Oliver NS, Zaharieva DP , Battelino T et al (2020) . Diabetologia, 63(12), 2501-2520.
Bradburn MJ, Lee EC, White DA, Hind D, Waugh NR, Cooke DD, Hopkins D, Mansell P & Heller SR (2020) . Journal of Clinical Epidemiology.
Heller S, Lingvay I, Marso SP, Philis�\Tsimikas A, Pieber TR, Poulter NR, Pratley RE, Hachmann�\Nielsen E, Kvist K, Lange M , Moses AC et al (2020) . Diabetes, Obesity and Metabolism.
Philis-Tsimikas A, Klonoff DC, Khunti K, Bajaj HS, Leiter LA, Hansen MV, Troelsen LN, Ladelund S, Heller S & Pieber TR (2020) . Diabetologia, 63(4), 698-710.
Heller SR, Gianfrancesco C, Taylor C & Elliott J (2020) . Diabetic Medicine, 37(4), 545-554.
Winkley K, Upsher R, Stahl D, Pollard D, Brennan A, Heller S & Ismail K (2020) . Diabetic Medicine.
Moran R, Butt J, Heller S, Hinks J, Kerridge L, Samuels M & Hanney S (2019) . Health Research Policy and Systems, 17(1).
Heller SR, Buse JB, Ratner R, Seaquist E, Bardtrum L, Hansen CT, Tutkunkardas D & Moses AC (2019) . Diabetes Care.
Johnson B, Norman P, Sanders T, Elliott J, Whitehead V, Campbell F, Hammond P, Ajjan R & Heller S (2019) . Diabetic Medicine.
Battelino T, Danne T, Bergenstal RM, Amiel SA, Beck R, Biester T, Bosi E, Buckingham BA, Cefalu WT, Close KL , Cobelli C et al (2019) . Diabetes Care, 42(8), 1593-1603.
Group TIHS, Amiel SA, Aschner P, Childs B, Cryer PE, de Galan BE, Frier BM, Gonder-Frederick L, Heller SR, Jones T , Khunti K et al (2019) . The Lancet Diabetes & Endocrinology, 7(5), 385-396.
Iqbal A, Prince LR, Novodvorsky P, Bernjak A, Thomas MR, Birch L, Lambert D, Kay LJ, Wright FJ, Macdonald IA , Jacques RM et al (2019) . Journal of Clinical Endocrinology and Metabolism, 104(4), 1187-1199.
Chow E, Iqbal A, Walkinshaw E, Phoenix F, Macdonald IA, Storey RF, Ajjan R & Heller SR (2018) . Diabetes Care, 41(12), 2625-2633.
Sanders T, Elliott J, Norman P, Johnson B & Heller S (2018) . Diabetic Medicine, 35(11), 1531-1537.
Mitchell SJ, Hine J, Vening J, Montague J, Evans S, Shaw KM, Frier BM, Heller SR & Russell-Jones DL (2017) . The Lancet Diabetes & Endocrinology, 5(9), 677-679.
Heller SR, Pratley RE, Sinclair A, Festa A, Kiljanski J, Brusko CS, Duan R & Heine RJ (2017) . Diabetes, Obesity and Metabolism.
Iqbal A & Heller SR (2017) . Diabetologia.
Heller S, Amiel S, Campbell M, Choudhary P, Cooper C, Dimairo M, Elliott J, Hammond P, Lee E, Lindsay R , Waugh N et al (2017) . BMJ, 356, ---.
The International Hypoglycaemia Study GroupEmail (2017) . Diabetologia, 60(1), 3-6.
International Hypoglycaemia Study Group (2017) . Diabetes Care, 40(1), 155-157.
Pieber TR, Deller S, Korsatko S, Jensen L, Christiansen E, Madsen J & Heller SR (2015) . Diabetes, Obesity and Metabolism, 17(8), 742-750.
Zoungas S, Chalmers J, Neal B, Billot L, Li Q, Hirakawa Y, Arima H, Monaghan H, Joshi R, Colagiuri S , Cooper ME et al (2014) . New England Journal of Medicine, 371(15), 1392-1406.
Chow E, Bernjak A, Williams S, Fawdry RA, Hibbert S, Freeman J, Sheridan PJ & Heller SR (2014) . Diabetes, 63(5), 1738-1747.
Little SA, Speight J, Leelarathna L, Walkinshaw E, Tan HK, Bowes A, Lubina-Solomon A, Chadwick TJ, Stocken DD, Brennand C , Marshall SM et al () . Diabetes Care, dc172682-dc172682.
Heller S, Lawton J, Amiel S, Cooke D, Mansell P, Brennan A, Elliott J, Boote J, Emery C, Baird W , Basarir H et al () . Programme Grants for Applied Research, 2(5), 1-188.

Conference proceedings papers

Philis-Tsimikas A, Klonoff DC, Khunti K, Bajaj HS, Leiter LA, Tutkunkardas D, Troelsen LN, Bak BA, Heller SR & Pieber TR (2019) Reduced risk of hypoglycaemia and lower HbA(1c) with degludec compared to glargine U300 in insulin-treated patients with type 2 diabetes. DIABETOLOGIA, Vol. 62 (pp S47-S47)
Heller SR, Bergenstal R, Cannon CP, Kupfer S, Wilson C, White WB & Investigators EXAMINE (2016) Hypoglycaemia is associated with increased risk of cardiovascular events: results from the EXAMINE trial. DIABETOLOGIA, Vol. 59 (pp S44-S44)
Thabit H, Elleri D, Leelarathna L, Allen J, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska M , Barnard K et al (2015) . The Lancet, Vol. 385 (pp S96-S96)
Chow E, Bernjak A, Sheridan PJ & Heller SR (2014) Cardiac autonomic regulation during acute experimental hypoglycaemia in type 2 diabetes. DIABETOLOGIA, Vol. 57 (pp S260-S261)

All publications

Journal articles

Holmes-Truscott E, Schipp J, Cooke DD, Hendrieckx C, Coates EJ, Heller SR & Speight J (2024) . Health and Quality of Life Outcomes, 22(1), 70.
Divilly P, Martine-Edith G, Zaremba N, S?holm U, Mahmoudi Z, Cigler M, Ali N, Abbink EJ, Br?sen J, de Galan B , Pedersen-Bjergaard U et al (2024) . Diabetes Care, 47(10), 1769-1777.
Johansen RF, Caunt S, Heller S, Sander SE, S?ndergaard E, Molsted S & Kristensen PL (2024) . Canadian Journal of Diabetes.
HELLER SR, GOPALAKRISHNAN UNNIKRISHNAN A, AKKUS O, LINJAWI S & SHAH MJ (2024) . Diabetes, 73(Supplement_1).
RIDDELL MC, HELLER SR, ASONG M, CARSTENSEN L, WATT SK & WOO VC (2024) . Diabetes, 73(Supplement_1).
Robertson E, Sutcliffe J, Connor R & Heller SR (2024) . Diabetic Medicine, 41(7).
Svensson CH, Fabricius TW, Verhulst CEM, Kristensen PL, Tack CJ, Heller SR, Amiel SA, McCrimmon RJ, Evans M, Holst JJ , de Galan BE et al (2024) . Diabetes, Obesity and Metabolism.
Rosenstock J, Bajaj HS, Lingvay I & Heller SR (2024) . BMJ Open Diabetes Research & Care, 12(3), e003930-e003930.
Berthon W, McGurnaghan SJ, Blackbourn LAK, Mellor J, Gibb FW, Heller S, Kennon B, McCrimmon RJ, Philip S, Sattar N , McKeigue PM et al (2024) . Diabetes Research and Clinical Practice, 210, 111642-111642.
Sander SE, Johansen RF, Caunt S, S?ndergaard E, Rolver MG, Sandb?k A, Heller S, Kristensen PL & Molsted S (2024) . Canadian Journal of Diabetes, 48(3), 204-210.e1.
Elneima O, McAuley HJC, Leavy OC, Chalmers JD, Horsley A, Ho L-P, Marks M, Poinasamy K, Raman B, Shikotra A , Singapuri A et al (2023) . International Journal of Epidemiology.
Brightling CE, Evans RA, Singapuri A, Smith N, Wain LV, Brightling CE, Evans RA, Wain LV, Chalmers JD, Harris VC , Ho LP et al (2023) . The Lancet Respiratory Medicine, 11(11), e93-e94.
Raman B, McCracken C, Cassar MP, Moss AJ, Finnigan L, Samat AHA, Ogbole G, Tunnicliffe EM, Alfaro-Almagro F, Menke R , Xie C et al (2023) . The Lancet Respiratory Medicine, 11(11), 1003-1019.
MAHMOUDI Z, DIVILLY P, MARTINE-EDITH G, BOIROUX D, ZAREMBA N, SOEHOLM U, GOMES M, VAAG AA, SPEIGHT J, DE GALAN BE , PEDERSEN-BJERGAARD U et al (2023) . Diabetes, 72(Supplement_1).
AMIEL SA, TOSCHI E, HELLER SR, STADLER MA, CHOUDHARY P & DE ZOYSA N (2023) . Diabetes, 72(Supplement_1).
S?holm U, Broadley M, Zaremba N, Divilly P, Nefs G, Carlton J, Mader JK, Baumann PM, Gomes M, Martine-Edith G , Pollard DJ et al (2023) . PLoS ONE, 18(3).
Ravindrarajah R, Sutton M, Reeves D, Cotterill S, Mcmanus E, Meacock R, Whittaker W, Soiland-Reyes C, Heller S, Bower P & Kontopantelis E (2023) . PLoS Medicine, 20(2).
Heller S, Battelino T, Bailey TS, Pieber TR, H?velmann U, Plum�\M?rschel L, Melgaard AE, Aronson R, DiMeglio LA, Johansen T & Danne T (2023) . Diabetes, Obesity and Metabolism.
Phillip M, Nimri R, Bergenstal RM, Barnard-Kelly K, Danne T, Hovorka R, Kovatchev BP, Messer LH, Parkin CG, Ambler-Osborn L , Amiel SA et al (2023) . Endocrine Reviews, 44(2), 254-280.
Seaquist ER, Teff K & Heller SR (2022) . Diabetes Care, 45(12), 2799-2805.
Chatwin H, Broadley M, Hendrieckx C, Carlton J, Heller S, Amiel SA, de Galan B, McCrimmon RJ, Pedersen-Bjergaard U, Pouwer F & Speight J (2022) . Journal of Diabetes and its Complications.
Divilly P, Zaremba N, Mahmoudi Z, S?holm U, Pollard DJ, Broadley M, Abbink EJ, de Galan B, Pedersen-Bjergaard U, Renard E , Evans M et al (2022) . Diabet Med, e14892.
Poole AP, Finnis ME, Anstey J, Bellomo R, Bihari S, Biradar V, Doherty S, Eastwood G, Finfer S, French CJ , Heller S et al (2022) . American Journal of Respiratory and Critical Care Medicine, 206(7), 874-882.
Amiel SA, Potts L, Goldsmith K, Jacob P, Smith EL, Gonder-Frederick L, Heller S, Toschi E, Brooks A, Kariyawasam D , Choudhary P et al (2022) . Nat Commun, 13(1), 2229.
Evans RA, Leavy OC, Richardson M, Elneima O, McCauley HJC, Shikotra A, Singapuri A, Sereno M, Saunders RM, Harris VC , Houchen-Wolloff L et al (2022) . The Lancet Respiratory Medicine.
Houchen-Wolloff L, Poinasamy K, Holmes K, Tarpey M, Hastie C, Raihani K, Rogers N, Smith N, Adams D, Burgess P , Clark J et al (2022) . Thorax, 77(7), 717-720.
Jacob P, Potts L, Maclean RH, de Zoysa N, Rogers H, Gonder-Frederick L, Smith EL, Kariyawasam D, Brooks A, Heller S , Toschi E et al (2022) . Diabetologia.
Maclean RH, Jacob P, Choudhary P, Heller SR, Toschi E, Kariyawasam D, Brooks A, Kendall M, de Zoysa N, Gonder-Frederick LA & Amiel SA (2022) . Diabetes Care.
Heller S & Novodvorsky P (2022) . Medicine.
Coolen M, Broadley M, Hendrieckx C, Chatwin H, Clowes M, Heller S, de Galan BE, Speight J & Pouwer F (2021) . PLoS ONE, 16(12).
Heller SR, Durrant A & Tandon N (2021) . The Lancet, 398(10313), 1785-1786.
Bernjak A, Iqbal A, Heller S & Clayton R (2021) Hypoglycaemia combined with mild hypokalaemia reduces the heart rate and causes abnormal pacemaker activity in a computational model of a human sinoatrial cell.. Journal of the Royal Society Interface, 18(184).
Pieber TR, Bajaj HS, Heller SR, Jia T, Khunti K, Klonoff DC, Ladelund S, Leiter LA, Wagner L & Philis-Tsimikas A (2021) . Diabetes, Obesity and Metabolism.
Matlock KA, Broadley M, Hendrieckx C, Clowes M, Sutton A, Heller SR, de Galan BE, Pouwer F, Speight J & Hypo-RESOLVE consortium (2021) . Diabetic Medicine.
Evans RA, McAuley H, Harrison EM, Shikotra A, Singapuri A, Sereno M, Elneima O, Docherty AB, Lone NI, Leavy OC , Daines L et al (2021) . The Lancet Respiratory Medicine, 9(11), 1275-1287.
Chatwin H, Broadley M, Valdersdorf Jensen M, Hendrieckx C, Carlton J, Heller S, Amiel S, de Galan B, Hermanns N, Finke-Groene K , Speight J et al (2021) . BMJ Open Diabetes Research & Care, 9(1), e002322-e002322.
HELLER SR, BATTELINO T, BAILEY TS, TEHRANCHI R, KLAFF LJ, PIEBER T, H?VELMANN U, PLUM-MOERSCHEL L, MELGAARD AE, ARONSON R , DIMEGLIO L et al (2021) . Diabetes, 70(Supplement_1).
SILVER RJ, ASONG M, BEGTRUP K, KOEFOED MM, HELLER SR & ROSENSTOCK J (2021) . Diabetes, 70(Supplement_1).
Nguyen TN, Harris K, Woodward M, Chalmers J, Cooper M, Hamet P, Harrap S, Heller S, MacMahon S, Mancia G , Marre M et al (2021) . Diabetes Care.
Moser O, Riddell MC, Eckstein ML, Adolfsson P, Rabasa-Lhoret R, van den Boom L, Gillard P, N?rgaard K, Oliver NS, Zaharieva DP , Battelino T et al (2021) . Diabetologia, 64, 935-938.
Fabricius TW, Verhulst CEM, Kristensen PL, Tack CJ, McCrimmon RJ, Heller S, Evans ML, Amiel SA, Pieber TR, de Galan BE & Pedersen-Bjergaard U (2021) . Diabetologia, 64(4), 727-736.
von Herrath M, Bain SC, Bode B, Clausen JO, Coppieters K, Gaysina L, Gumprecht J, Hansen TK, Mathieu C, Morales C , Mosenzon O et al (2021) . The Lancet Diabetes and Endocrinology, 9(4), 212-224.
Chatwin H, Broadley M, Speight J, Cantrell A, Sutton A, Heller S, de Galan B, Hendrieckx C & Pouwer F (2021) . Diabetes Research and Clinical Practice, 174, 108752-108752.
Stanton�\Fay SH, Hamilton K, Chadwick PM, Lorencatto F, Gianfrancesco C, de Zoysa N, Coates E, Cooke D, McBain H, Heller SR & Michie S (2021) . Diabetic Medicine.
Ali Abdelhamid Y, Bernjak A, Phillips LK, Summers MJ, Weinel LM, Lange K, Chow E, Kar P, Horowitz M, Heller S & Deane AM (2021) . Critical Care Medicine, 49(4), 636-649.
Carlton J, Leaviss J, Pouwer F, Hendrieckx C, Broadley MM, Clowes M, McCrimmon RJ, Heller SR & Speight J (2021) . Diabetologia.
Bernjak A, Novodvorsky P, Chow E, Iqbal A, Sellors L, Williams S, Fawdry RA, Marques JLB, Jacques RM, Campbell MJ , Sheridan PJ et al (2021) . Diabetes & Metabolism, 101237-101237.
Phillip M, Mathieu C, Lind M, Araki E, Bartolo P, Bergenstal R, Heller S, Hansen L, Scheerer MF, Thoren F , Arya N et al (2021) . Diabetes, Obesity and Metabolism, 23(2), 549-560.
Coates E, Amiel S, Baird W, Benaissa M, Brennan A, Campbell M, Chadwick P, Chater T, Choudhary P, Cooke D , Cooper C et al (2021) . BMJ Open, 11(1).
Moser O, Riddell MC, Eckstein ML, Adolfsson P, Rabasa-Lhoret R, van den Boom L, Gillard P, N?rgaard K, Oliver NS, Zaharieva DP , Battelino T et al (2020) . Diabetologia, 63(12), 2501-2520.
Ravindrarajah R, Reeves D, Howarth E, Meacock R, Soiland-Reyes C, Cotterill S, Whittaker W, Heller S, Sutton M, Bower P & Kontopantelis E (2020) . BMJ Open, 10(9), e040201-e040201.
Everett CC, Reynolds C, Fernandez C, Stocken DD, Sharples LD, Sathyapalan T, Heller S, Storey RF & Ajjan RA (2020) . Diabetes and Vascular Disease Research, 17(5).
Heller SR, Peyrot M, Oates SK & Taylor AD (2020) . BMJ Open Diabetes Research & Care, 8(1).
Winkley K, Upsher R, Stahl D, Pollard D, Kasera A, Brennan A, Heller S & Ismail K (2020) . Health Technology Assessment, 24(28).
MACLEAN RH, JACOB P, HAYWOOD S, CHOUDHARY P, HELLER SR, TOSCHI E, KARIYAWASAM D, ANDERBRO TC & AMIEL SA (2020) . Diabetes, 69(Supplement_1).
Bradburn MJ, Lee EC, White DA, Hind D, Waugh NR, Cooke DD, Hopkins D, Mansell P & Heller SR (2020) . Journal of Clinical Epidemiology.
Winkley K, Upsher R, Stahl D, Pollard D, Brennan A, Heller SR & Ismail K (2020) . BMJ Open Diabetes Research & Care, 8(1).
Heller S, Lingvay I, Marso SP, Philis�\Tsimikas A, Pieber TR, Poulter NR, Pratley RE, Hachmann�\Nielsen E, Kvist K, Lange M , Moses AC et al (2020) . Diabetes, Obesity and Metabolism.
Philis-Tsimikas A, Klonoff DC, Khunti K, Bajaj HS, Leiter LA, Hansen MV, Troelsen LN, Ladelund S, Heller S & Pieber TR (2020) . Diabetologia, 63(4), 698-710.
Sinclair AJ, Heller SR, Pratley RE, Duan R, Heine RJ, Festa A & Kilja��ski J (2020) . Diabetes, Obesity and Metabolism.
Heller SR, Gianfrancesco C, Taylor C & Elliott J (2020) . Diabetic Medicine, 37(4), 545-554.
Bernjak A, Chow E, Robinson EJ, Freeman J, Marques JLB, Macdonald IA, Sheridan PJ & Heller SR (2020) . Diabetologia.
Winkley K, Upsher R, Stahl D, Pollard D, Brennan A, Heller S & Ismail K (2020) . Diabetic Medicine.
Galan BE, McCrimmon RJ, Ibberson M, Heller SR, Choudhary P, Pouwer F, Speight J, Carlton J, Pieber TR, Rosilio M , Tack CJ et al (2020) . Diabetic Medicine.
Philis�\Tsimikas A, Lane W, Pedersen�\Bjergaard U, Wysham C, Bardtrum L, Harring S & Heller S (2020) . Diabetes, Obesity and Metabolism.
Seaquist ER, Blonde L, McGill JB, Heller SR, Kendall DM, Bumpass JB, Pompilio FM & Grant ML (2020) . Diabetic Medicine, 37(5), 752-759.
Flatt AJS, Little SA, Speight J, Leelarathna L, Walkinshaw E, Tan HK, Bowes A, Lubina-Solomon A, Holmes-Truscott E, Chadwick TJ , Wood R et al (2020) . Diabetes Care, 43(1), 44-52.
Heller S, Lingvay I, Marso SP, Philis�\Tsimikas A, Pieber TR, Poulter NR, Pratley RE, Hachmann�\Nielsen E, Kvist K, Lange M , Moses AC et al (2020) . Diabetes, Obesity and Metabolism, 22(12), 2248-2256.
Moran R, Butt J, Heller S, Hinks J, Kerridge L, Samuels M & Hanney S (2019) . Health Research Policy and Systems, 17(1).
Heller SR, Buse JB, Ratner R, Seaquist E, Bardtrum L, Hansen CT, Tutkunkardas D & Moses AC (2019) . Diabetes Care.
Johnson B, Norman P, Sanders T, Elliott J, Whitehead V, Campbell F, Hammond P, Ajjan R & Heller S (2019) . Diabetic Medicine.
Speight J, Holmes-Truscott E, Little SA, Leelarathna L, Walkinshaw E, Tan HK, Bowes A, Kerr D, Flanagan D, Heller SR , Evans ML et al (2019) . Diabetes Technology & Therapeutics, 21(11), 619-626.
Battelino T, Danne T, Bergenstal RM, Amiel SA, Beck R, Biester T, Bosi E, Buckingham BA, Cefalu WT, Close KL , Cobelli C et al (2019) . Diabetes Care, 42(8), 1593-1603.
Mosenzon O, Blicher TM, Rosenlund S, Eriksson JW, Heller S, Hels OH, Pratley R, Sathyapalan T, Desouza C, Abramof R , Alpenidze D et al (2019) . The Lancet Diabetes & Endocrinology, 7(7), 515-527.
Heller SR, DeVries JH, Wysham C, Hansen CT, Hansen MV & Frier BM (2019) . Diabetes, Obesity and Metabolism, 21(7), 1634-1641.
Pollock RF, Heller S, Pieber TR, Woo V, Gundgaard J, Hall��n N, Luckevich M, Tutkunkardas D & Zinman B (2019) . Diabetes, Obesity and Metabolism, 21(7), 1706-1714.
Amiel SA, Choudhary P, Jacob P, Smith EL, De Zoysa N, Gonder-Frederick L, Kendall M, Heller S, Brooks A, Toschi E , Kariyawasam D et al (2019) . BMJ Open, 9(6), e030356-e030356.
Heller SR (2019) . Diabetes Care, 42(6), 1005-1008.
Group TIHS, Amiel SA, Aschner P, Childs B, Cryer PE, de Galan BE, Frier BM, Gonder-Frederick L, Heller SR, Jones T , Khunti K et al (2019) . The Lancet Diabetes & Endocrinology, 7(5), 385-396.
Sanders T, Elliott J, Norman P, Johnson B & Heller S (2019) . Sociology of Health & Illness, 41(7), 1289-1304.
Iqbal A, Prince LR, Novodvorsky P, Bernjak A, Thomas MR, Birch L, Lambert D, Kay LJ, Wright FJ, Macdonald IA , Jacques RM et al (2019) . Journal of Clinical Endocrinology and Metabolism, 104(4), 1187-1199.
Dunkley AJ, Fitzpatrick C, Gray LJ, Waheed G, Heller SR, Frier BM, Davies MJ, Khunti K & Group OBOTPCDS (2019) . Diabetes Obesity and Metabolism.
Danne T, Garg S, Peters AL, Buse JB, Mathieu C, Pettus JH, Alexander CM, Battelino T, Ampudia-Blasco FJ, Bode BW , Cariou B et al (2019) . Diabetes Care, 42(6), 1147-1154.
Heller S & Novodvorsky P (2019) . Medicine, 47(1), 52-58.
Bowering K, Rodbard HW, Russell-Jones D, Bode B, Harris S, Piletic M, Heller S, Woo V, Babu V, Dethlefsen C & Mathieu C (2019) . Diabetes Therapy, 10(1), 177-188.
Heller S, Meneghini L, Nikolajsen A, Kragh N, Lewis HB, Saretsky T, Kosmas CE & Lloyd A (2019) . Current Medical Research and Opinion, 35(3), 525-533.
Chow E, Iqbal A, Walkinshaw E, Phoenix F, Macdonald IA, Storey RF, Ajjan R & Heller SR (2018) . Diabetes Care, 41(12), 2625-2633.
Campbell F, Lawton J, Rankin D, Clowes M, Coates E, Heller S, De Zoysa N, Elliott J & Breckenridge J (2018) . BMC Health Services Research, 18.
DeVries JH, Bailey TS, Bhargava A, Gerety G, Gumprecht J, Heller S, Lane W, Wysham CH, Zinman B, Bak BA , Hachmann-Nielsen E et al (2018) . Diabetes, Obesity and Metabolism.
Sanders T, Elliott J, Norman P, Johnson B & Heller S (2018) . Diabetic Medicine, 35(11), 1531-1537.
White WB, Jalil F, Cushman WC, Bakris GL, Bergenstal R, Heller SR, Liu Y, Mehta C, Zannad F & Cannon CP (2018) . Journal of the American Heart Association, 7(20).
Heller S, Bowering K, Raskin P, Liebl A, Buchholtz K, Gorst-Rasmussen A & Pieber TR (2018) . Diabetic Medicine, 35(9), 1273-1278.
Novodvorsky P, Bernjak A, Robinson EJ, Iqbal A, Macdonald IA, Jacques RM, Marques JLB, Sheridan PJ & Heller SR (2018) . Diabetic Medicine, 35(9), 1264-1272.
HELLER SR, HANS DEVRIES J, WYSHAM CH, HANSEN CT, HANSEN MV & FRIER BM (2018) . Diabetes, 67(Supplement_1).
Korsatko S, Jensen L, Brunner M, Sach�\Friedl S, Tarp MD, Holst AG, Heller SR & Pieber TR (2018) . Diabetes, Obesity and Metabolism, 20(11), 2565-2573.
Pratley RE, Rosenstock J, Heller SR, Sinclair A, Heine RJ, Kilja��ski J, Brusko CS, Duan R & Festa A (2018) . Journal of Diabetes Science and Technology, 12(6), 1184-1191.
Pollock RF, Chubb B, Valentine WJ & Heller S (2018) . Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 11, 217-226.
Iqbal A, Novodvorsky P & Heller SR (2018) . Diabetes and Metabolism Journal, 42(2), 177-177.
Cavender MA, White WB, Liu Y, Massaro JM, Bergenstal RM, Mehta CR, Zannad F, Heller S, Cushman WC & Cannon CP (2018) . Clinical Cardiology.
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White WB, Heller SR, Cannon CP, Howitt H, Khunti K & Bergenstal RM (2018) . The American Journal of Medicine, 131(7), 813-819.e5.
Chatterjee S, Davies MJ, Heller S, Speight J, Snoek FJ & Khunti K (2018) . The Lancet Diabetes & Endocrinology, 6(2), 91-92.
Iqbal A, Novodvorsky P & Heller SR (2018) . Diabetes and Metabolism Journal, 42(1), 3-18.
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Heller S, Mathieu C, Kapur R, Wolden ML & Zinman B (2016) . Diabetic Medicine, 33(4), 478-487.
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Speight J, Barendse SM, Singh H, Little SA, Inkster B, Frier BM, Heller SR, Rutter MK & Shaw JAM (2016) . Diabetic Medicine, 33(3), 376-385.
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Kruger J, Pollard DJ, Basarir H, Thokala P, Cooke D, Clark M, Bond R, Heller S & Brennan A (2015) . Medical Decision Making, 35(7), 872-887.
Heller S, Houwing N, Kragh N, Ploug UJ, Nikolajsen A & Alleman CJM (2015) . Diabetes Therapy, 6(3), 389-393.
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Eborall HC, Dallosso HM, McNicol S, Speight J, Khunti K, Davies MJ & Heller SR (2015) . Family Practice, 32(5), 596-602.
Treasure J, Kan C, Stephenson L, Warren E, Smith E, Heller S & Ismail K (2015) . Diabetic Medicine, 32(12), 1541-1545.
Cooke D, Bond R, Lawton J, Rankin D, Heller S, Clark M & Speight J (2015) . Journal of Behavioral Medicine, 38(5), 817-829.
Elwen FR, Huskinson A, Clapham L, Bottomley MJ, Heller SR, James C, Abbas A, Baxter P & Ajjan RA (2015) . BMJ Open Diabetes Research & Care, 3(1).
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Young AJ, Thabit H, Heller SR, Evans ML, Amiel SA, Hovorka R & Barnard KD (2015) . Journal of Diabetes Science and Technology, 9(4), 932-933.
Dallosso HM, Bodicoat DH, Campbell M, Carey ME, Davies MJ, Eborall HC, Hadjiconstantinou M, Khunti K, Speight J & Heller S (2015) . Diabetic Medicine, 32(3), 414-422.
Elliott J, Rankin D, Jacques RM, Lawton J, Emery CJ, Campbell MJ, Dixon S & Heller SR (2015) . Diabetic Medicine, 32(3), 391-398.
Ayling K, Brierley S, Johnson B, Heller S & Eiser C (2015) . Psychology & Health, 30(1), 85-103.
Barnard KD, Wysocki T, Thabit H, Evans ML, Amiel S, Heller S, Young A & Hovorka R (2015) . Diabetic Medicine, 32(5), 601-608.
Ayling K, Brierley S, Johnson B, Heller S & Eiser C (2015) . British Journal of Health Psychology, 20(2), 428-446.
Morrow DA, Cannon CP, Zannad F, Cushman WC, Bakris GL, Nissen SE, Heller SR, Bergenstal RM, Perez AT, Fleck PR , Mehta CR et al (2014) . Circulation, 130(suppl_2).
Carey ME, Mandalia PK, Daly H, Gray LJ, Hale R, Martin Stacey L, Taub N, Skinner TC, Stone M, Heller S , Khunti K et al (2014) . Diabetic Medicine, 31(11), 1431-1438.
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Ridge K, Thomas S, Jackson P, Pender S, Heller S, Treasure J & Ismail K (2014) . Diabetic Medicine, 31(1), 55-60.
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White WB, Cannon CP, Heller SR, Nissen SE, Bergenstal RM, Bakris GL, Perez AT, Fleck PR, Mehta CR, Kupfer S , Wilson C et al (2013) . New England Journal of Medicine, 369(14), 1327-1335.
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Price KJ, Wales J, Eiser C, Knowles J, Heller S, Freeman J, Brennan A, McPherson A & Wellington J (2013) . BMJ Open, 3(1).
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Cryer PE (2013) . Annals of Internal Medicine, 158(6), 500-500.
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Dallosso HM, Eborall HC, Daly H, Martin-Stacey L, Speight J, Realf K, Carey ME, Campbell MJ, Dixon S, Khunti K , Davies MJ et al (2012) . BMC Family Practice, 13.
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Perdomo OJ, Robinson EJ, Suzuki DOH, Heller SR & Marques JLB (2012) . 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.
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Elliott J, Heller SR, Hopkinson HE & Mansell P (2012) Does duration of type 1 diabetes affect the outcomes of structured education?. DIABETOLOGIA, 55, S100-S100.
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Rankin D, Heller S & Lawton J (2011) . Patient Education and Counseling, 83(1), 87-91.
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Kengne AP, Patel A, Colagiuri S, Heller S, Hamet P, Marre M, Pan CY, Zoungas S, Grobbee DE, Neal B , Chalmers J et al (2010) . Diabetologia, 53(5), 821-831.
Gillett M, Dallosso HM, Dixon S, Brennan A, Carey ME, Campbell MJ, Heller S, Khunti K, Skinner TC & Davies MJ (2010) . BMJ, 341(aug20 1), c4093-c4093.
Zoungas S, De Galan BE, Ninomiya T, Grobbee D, Hamet P, Heller S, MacMahon S, Marre M, Neal B, Patel A , Woodward M et al (2009) . Diabetes Care, 32(11), 2068-2074.
de Galan BE, Zoungas S, Chalmers J, Anderson C, Dufouil C, Pillai A, Cooper M, Grobbee DE, Hackett M, Hamet P , Heller SR et al (2009) . Diabetologia, 52(11), 2328-2336.
Heller SR (2009) . Diabetes Care, 32(suppl_2), S357-S361.
Heller S, Koenen C & Bode B (2009) . Clinical Therapeutics, 31(10), 2086-2097.
Hansen MV, Pedersen-Bjergaard U, Heller SR, Wallace TM, Rasmussen ?K, J?rgensen HV, Pramming S & Thorsteinsson B (2009) . Diabetes Research and Clinical Practice, 85(2), 183-188.
Choudhary P, Lonnen K, Emery CJ, MacDonald IA, MacLeod KM, Amiel SA & Heller SR (2009) . Diabetic Medicine, 26(7), 665-672.
Cryer PE, Axelrod L, Grossman AB, Heller SR, Montori VM, Seaquist ER & Service FJ (2009) . The Journal of Clinical Endocrinology & Metabolism, 94(3), 709-728.
Heller SR (2009) . The British Journal of Diabetes & Vascular Disease, 9(6), 269-272.
Heller SR (2008) . Diabetes Research and Clinical Practice, 82, S108-S111.
Heller SR (2008) . Diabetes, 57(12), 3177-3183.
Waller H, Eiser C, Knowles J, Rogers N, Wharmby S, Heller S, Hall C, Greenhalgh S, Tinklin T, Metcalfe C , Millard E et al (2008) . Archives of Disease in Childhood, 93(11), 927-931.
Robinson EJ, Marques JLB & Heller SR (2008) Can spectral analysis of heart rate variability detect subclinical autonomic dysfunction as reliably as spontaneous baroreceptor sensitivity?. DIABETOLOGIA, 51, S500-S500.
Munir A, Choudhary P, Harrison B, Heller S & Newell-Price J (2008) . Clinical Endocrinology, 68(6), 912-918.
Davies MJ, Heller S, Skinner TC, Campbell MJ, Carey ME, Cradock S, Dallosso HM, Daly H, Doherty Y, Eaton S , Fox C et al (2008) . BMJ, 336(7642), 491-495.
Khunti K, Skinner TC, Heller S, Carey ME, Dallosso HM & Davies MJ (2008) . Diabetic Medicine, 25(12), 1454-1461.
Davies MJ, Heller S, Khunti K & Skinner TC (2008) . Chronic Illness, 4(1), 38-40.
(2008) . New England Journal of Medicine, 358(24), 2560-2572.
Ferrari GL, Marques JLB, Gandhi RA, Emery CJ, Tesfaye S, Heller SR, Schneider FK & Gamba HR (2007) An approach to the assessment of diabetic neuropathy based on dynamic pupillometry.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 557-560.
Heller S, Kozlovski P & Kurtzhals P (2007) . Diabetes Research and Clinical Practice, 78(2), 149-158.
Moustafa M, Bullock AJ, Creagh FM, Heller S, Jeffcoate W, Game F, Amery C, Tesfaye S, Ince Z, Haddow DB & MacNeil S (2007) . Regenerative Medicine, 2(6), 887-902.
Heller SR (2007) . BMJ, 335(7611), 105-106.
(2007) . Diabetologia, 50(6), 1140-1147.
McNally PG, Dean JD, Morris AD, Wilkinson PD, Compion G & Heller SR (2007) . Diabetes Care, 30(5), 1044-1048.
Mathiesen ER, Kinsley B, Amiel SA, Heller S, McCance D, Duran S, Bellaire S & Raben A (2007) . Diabetes Care, 30(4), 771-776.
Leeds JS, Sanders DS, Mackie AD, Song SH, Creagh FM, Hardisty CA, Scott AR, Heller SR, Caddick SL & Tesfaye S (2007) A prospective study of the prevalence of gastrointestinal symptoms in patients with Type 1 diabetes and correlation with diabetes control and quality of life. DIABETIC MEDICINE, 24, 65-65.
Glasziou P, Alexander J, Beller E & Clarke P (2007) . Health and Quality of Life Outcomes, 5(1), 21-21.
Fraser R & Heller SR (2007) . Obstetrics, Gynaecology & Reproductive Medicine, 17(12), 345-348.
Ferrari GL, Marques JLB, Gandhi RA, Emery CJ, Tesfaye S, Heller SR, Schneider FK & Gamba HR (2007) . 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.
Skinner TC, Carey ME, Cradock S, Daly H, Davies MJ, Doherty Y, Heller S, Khunti K & Oliver L (2006) . Patient Education and Counseling, 64(1-3), 369-377.
Knowles J, Waller H, Eiser C, Heller S, Roberts J, Lewis M, Wilson K, Hutchinson T, Willan M, Bavelja P , Bennet G et al (2006) . Pediatric Diabetes, 7(6), 322-328.
Kolendorf K, Ross GP, Pavlic-Renar I, Perriello G, Philotheou A, Jendle J, Gall M-A & Heller SR (2006) . Diabetic Medicine, 23(7), 729-735.
Heller SR & Nicholson AN (2006) Aircrew and type 1 diabetes mellitus. Aviation Space and Environmental Medicine, 77(4), 456-458.
Alexakis C, Rodrigues M, Saatchi R, Nyongesa HO, Davies C, Ireland RH, Harris ND & Heller SR (2006) A knowledge-based electrocardiogram-monitoring system for detection of the onset of nocturnal hypoglycaemia in type 1 diabetic patients. Computers in Cardiology, 33, 5-8.
Heller SR (2006) . Medicine, 34(3), 107-110.
Heller SR & Dinneen SF (2006) . Medicine, 34(2), 80-82.
Amiel SA, Heller SR, Macdonald IA, Schwartz SL, Klaff LJ, Ruggles JA, Weyer C, Kolterman OG & Maggs DG (2005) . Diabetes, Obesity and Metabolism, 7(5), 504-516.
Heller S (2005) . Diabetic Medicine, 22(s3), 11-13.
Lee SP, Harris ND, Robinson RT, Davies C, Ireland R, Macdonald IA & Heller SR (2005) . Diabetologia, 48(7), 1269-1272.
Waller H, Eiser C, Heller S, Knowles J & Price K (2005) . Child: Care, Health and Development, 31(3), 283-289.
Heller S (2004) . Diabetic Medicine, 21(12), 1261-1262.
Pedersen-Bjergaard U, Pramming S, Heller SR, Wallace TM, Rasmussen ?K, J?rgensen HV, Matthews DR, Hougaard P & Thorsteinsson B (2004) . Diabetes/Metabolism Research and Reviews, 20(6), 479-486.
Murphy NP, Ford-Adams ME, Ong KK, Harris ND, Keane SM, Davies C, Ireland RH, MacDonald IA, Knight EJ, Edge JA , Heller SR et al (2004) . Diabetologia, 47(11), 1940-1947.
Heller S & Kinmonth AL (2004) . Diabetic Medicine, 21(10), 1061-1063.
Weaver JU, Robertson D & Atkin SL (2004) . Diabetes, Obesity and Metabolism, 6(5), 344-352.
Heise T, Heinemann L, Heller S, Weyer C, Wang Y, Strobel S, Kolterman O & Maggs D (2004) . Metabolism, 53(9), 1227-1232.
Heller S (2004) . Diabetes Research and Clinical Practice, 65, S23-S27.
Moustafa M, Simpson C, Glover M, Dawson RA, Tesfaye S, Creagh FM, Haddow D, Short R, Heller S & MacNeil S (2004) . Diabetic Medicine, 21(7), 786-789.
Heller SR, Colagiuri S, Vaaler S, Wolffenbuttel BHR, Koelendorf K, Friberg HH, Windfeld K & Lindholm A (2004) . Diabetic Medicine, 21(7), 769-775.
Lee SP, Yeoh L, Harris ND, Davies CM, Robinson RT, Leathard A, Newman C, Macdonald IA & Heller SR (2004) . Diabetes, 53(6), 1535-1542.
Robinson RTCE, Harris ND, Ireland RH, Macdonald IA & Heller SR (2004) . Diabetologia, 47(2), 312-315.
Shearer A, Bagust A, Sanderson D, Heller S & Roberts S (2004) . Diabetic Medicine, 21(5), 460-467.
MacNeil S, Moustafa M, Short RD, Haddow DB, Jarmalowicz M, Simpson C, Warner R, Glover M, Creagh FM, Heller S , Ralston D et al (2004) Clinical evaluation of a plasma polymer surface for culture and transfer of keratinocytes for chronic wounds. Transactions - 7th World Biomaterials Congress, 1068.
Mumme T, Reinartz P, Wirtz D, Niethard FU, B��ll U & Cremerius U (2003) . Nuklearmedizin, 42(06), 234-239.
Heller S (2003) . Expert Opinion on Pharmacotherapy, 4(8), 1407-1416.
Robinson RTCE, Harris ND, Ireland RH, Lee S, Newman C & Heller SR (2003) . Diabetes, 52(6), 1469-1474.
Evans AT (2003) . Evidence-Based Medicine, 8(3), 80-80.
Heller S (2003) . Diabetic Medicine, 20(3), 173-174.
Lee S, Harris ND, Robinson RT, Yeoh L, Macdonald IA & Heller SR (2003) . European Journal of Clinical Investigation, 33(2), 93-98.
Heller SR (2002) Cardiac arrhythmias in hypoglycaemia. Diabetes, Nutrition and Metabolism - Clinical and Experimental, 15(6), 461-467.
DAFNE Study Group (2002) . BMJ, 325(7367), 746-746.
Heller SR (2002) What we know about counterregulation in Type 2 diabetes. Diabetes, Nutrition and Metabolism - Clinical and Experimental, 15(5), 372-376.
Heller S (2002) . International Journal of Obesity, 26(S3), S31-S36.
Heller SR (2002) Abnormalities of the electrocardiogram during hypoglycaemia: The cause of the dead in bed syndrome?. International Journal of Clinical Practice, Supplement(129), 27-32.
Clowes JA, Robinson RT, Heller SR, Eastell R & Blumsohn A (2002) . Journal of Clinical Endocrinology and Metabolism, 87(7), 3324-3329.
Clowes JA (2002) . Journal of Clinical Endocrinology & Metabolism, 87(7), 3324-3329.
Heller S (2002) . Diabetic Medicine, 19(4), 263-264.
Heller SR, Amiel SA, Evans ML, Kong M-F, Macdonald IA & Peacey SR (2002) . Diabetes, Obesity and Metabolism, 4(2), 106-112.
Heller S, Kurtzhals P, Verge D & Lindholm A (2002) . Expert Opinion on Pharmacotherapy, 3(2), 183-195.
Heller SR & Dinneen SF (2002) . Medicine, 30(2), 66-67.
Heller SR (2002) . Medicine, 30(2), 54-57.
Heller SR (2002) . Current Medical Research and Opinion, 18(sup1), s40-s47.
Heller SR (2001) . Diabetic Medicine, 18(9), 689-689.
Clowes JA, Robinson RT, Eagleton A, Heller SR, Eastell R & Blumsohn A (2001) Acute hypoglycemia suppresses parathyroid hormone and bone turnover markers: An insulin clamp study.. JOURNAL OF BONE AND MINERAL RESEARCH, 16, S403-S403.
Price A, Obel O, Cresswell J, Catch I, Rutter S, Barik S, Heller SR & Weetman AP (2001) . Clinica Chimica Acta, 308(1-2), 91-98.
Heller S (2001) . Practical Diabetes International, 18(SUPPL.).
Heller SR (2000) . Diabetic Medicine, 17(12), 819-819.
Lee SPC, Harris ND, Yeoh LS, Macdonald IA & Heller SR (2000) Effect of intravenous adrenaline on cardiac repolarization in healthy males - Increases in corrected QT duration occur independently of hypokalaemia. JOURNAL OF PHYSIOLOGY-LONDON, 528P, 42P-42P.
Morris BW, Kouta S, Robinson R, MacNeil S & Heller S (2000) . Diabetic Medicine, 17(9), 684-685.
Pramming S, Pedersen-Bjergaard U, Heller SR, Wallace T, Rasmussen AK, Jorgensen HV, Matthews DR & Thorsteinsson B (2000) Severe hypoglycaemia in unselected patients with type 1 diabetes: A cross-sectional multicentre survey. DIABETOLOGIA, 43, A194-A194.
Peacey SR, Robinson R, Bedford C, Harris ND, Macdonald IA, Holman RR & Heller SR (2000) . Diabetes Care, 23(7), 1022-1023.
(2000) . Diabetic Medicine, 17(6), 413-413.
(2000) . Diabetic Medicine, 17(5), 335-335.
Ireland RH, Robinson RTCE, Heller SR, Marques JLB & Harris ND (2000) . Physiological Measurement, 21(2), 295-303.
Heller SR & Robinson RTCE (2000) . Diabetes, Obesity and Metabolism, 2(2), 75-82.
(2000) . Diabetic Medicine, 17(1), 1-1.
Jenkins RC (2000) . Clinical Endocrinology, 52(2), 187-187.
Heller SR (2000) Sudden cardiac death in young people with diabetes. CME Bulletin Endocrinology and Diabetes, 3(1), 4-7.
Heller SR, Amiel SA & Mansell P (1999) . Diabetes Care, 22(10), 1607-1611.
Heller S (1999) Dead in bed. Diabetic Medicine, 16(9), 782-785.
(1999) . Diabetic Medicine, 16(8), 623-625.
Robinson RTCE, Ireland NH, Harris ND, Bedford C, Fairclough E, Hudson S & Heller SR (1999) A comparison of the metabolic and cardiac electrophysiophysiological changes during experimental and clinical hypoglycaemia.. DIABETOLOGIA, 42, A71-A71.
Heller SR, Robinson RTCE, Harris ND, Ireland RH & Lindholm A (1999) Soluble insulin and the rapid -acting analogue insulin aspart have similar effects upon ventricular repolarization.. DIABETOLOGIA, 42, A237-A237.
Morris BW, MacNeil S, Hardisty CA, Heller S, Burgin C & Gray TA (1999) . Journal of Trace Elements in Medicine and Biology, 13(1-2), 57-61.
Heller SR (1999) . Best Practice & Research Clinical Endocrinology & Metabolism, 13(2), 279-294.
Dixon RM, Heller S, Harris N, Camplin DA & Grubb PA (1999) . Health Informatics Journal, 5(4), 200-204.
Heller SR & Robinson RTC (1999) , 4-26.
Rostami-Hodjegan A, Peacey SR, George E, Heller SR & Tucker GT (1998) Population-based modeling to demonstrate extrapancreatic effects of tolbutamide. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 274(4), E758-E771.
Rostami-Hodjegan A, Peacey SR, George E, Heller SR & Tucker GT (1998) . American Journal of Physiology-Endocrinology and Metabolism, 274(4), E758-E771.
Stroud CR, Heller SR, Ward JD, Hardisty CA & Weetman AP (1997) . QJM, 90(9), 577-585.
Marques JLB, George E, Peacey SR, Harris ND, Macdonald IA, Cochrane T & Heller SR (1997) . Diabetic Medicine, 14(8), 648-654.
George E, Marques JL, Harris ND, Macdonald IA, Hardisty CA & Heller SR (1997) . Diabetes Care, 20(8), 1293-1298.
George E, Bedford C, Peacey SR, Hardisty CA & Heller SR (1997) . Diabetic Medicine, 14(6), 442-448.
Dornan TL, Grenfell A, Heller SR, Morrish N, Scarpello J & Tooke J (1997) . Diabetic Medicine, 14(4), 275-278.
Peacey SR (1997) . Journal of Clinical Endocrinology & Metabolism, 82(5), 1458-1461.
Rostami-Hodjegan A, Peacey SR, George E, Heller SR & Tucker GT (1996) The insulinergic effect of tolbutamide during euglycaemic clamp in non-diabetic subjects: Pharmacokinetic-pharmacodynamic modelling. British Journal of Clinical Pharmacology, 41(5).
Harris ND, Baykouchev SB, Marques JLB, Cochrane T, George E, Heller SR & Ward JD (1996) . Journal of Medical Engineering & Technology, 20(6), 196-202.
Apfel J, Coles C, Crace C, Cradock S, Day J, Durrant S, Elster B, Felton AM, Finn L, Hatcher T , Heller S et al (1996) Training and professional development in diabetes care. Diabetic Medicine, 13(SUPPL. 4).
Apfel J, Coles C, Crace C, Cradock S, Day J, Durrant S, Elster B, Felton AM, Finn L, Hatcher T , Heller S et al (1996) Training and professional development in diabetes care.. Diabet Med, 13(9 Suppl 4), S65-S76.
Marques JLB, Harris ND, Marlow S, Bedford C, Cochrane T & Heller SR (1996) Abnormalities on the ECG during spontaneous overnight hypoglycaemia in patients with type 1 diabetes. DIABETOLOGIA, 39, 824-824.
Harris ND, Marques JLB, George E, Bedford C & Heller SR (1996) In search of a hypoglycaemic alarm. DIABETOLOGIA, 39, 832-832.
Peacey SR, Bedford C, Marlow S, Harris N, Hardisty CA, Macdonald IA & Heller SR (1996) Impaired peripheral physiological responses to hypoglycaemia in insulin treated type II diabetes. DIABETOLOGIA, 39, 243-243.
Heller SR, Rostamihodjegan A, Peacy SA & Tucker GT (1996) Fasting insulin predicts the acute insulinergic effect of tolbutamide, which is not related to hypoglycaemic effect.. DIABETOLOGIA, 39, 870-870.
RostamiHodjegan A, Peacy SA, Heller SR & Tucker GT (1996) Tolbutamide enhances glucose effectiveness following acute administration in non-diabetic subjects.. DIABETOLOGIA, 39, 869-869.
Amiel SA & Heller SR (1996) . The Lancet, 348(9019), 60-61.
Peacey SR, George E, Rostami-Hodjegan A, Bedford C, Harris N, Hardisty CA, Tucker GT, Macdonald IA & Heller SR (1996) . Diabetic Medicine, 13(7), 634-641.
Heller SR & Macdonald IA (1996) . Diabetic Medicine, 13(7), 607-615.
Price A (1996) . Journal of Clinical Endocrinology & Metabolism, 81(3), 1160-1163.
George E, Harris N, Bedford C, Macdonald IA, Hardisty CA & Heller SR (1995) . Diabetologia, 38(10), 1183-1190.
George E, Harris N, Bedford C, Macdonald IA, Hardisty CA & Heller SR (1995) . Diabetologia, 38(10), 1183-1190.
HELLER SR, MARQUES JLB, GEORGE E, HARRIS ND & COCHRANE T (1995) QTC INTERVAL PROLONGATION DURING HYPOGLYCEMIA IN PATIENTS WITH IDDM - A POSSIBLE MECHANISM OF SUDDEN-DEATH. DIABETOLOGIA, 38, A18-A18.
GEORGE E, MARQUES J, HARRIS N, HARDISTY CA & HELLER SR (1995) PHYSIOLOGICAL-RESPONSES TO HYPOGLYCEMIA ARE NOT REDUCED 2 DAYS AFTER ANTECEDENT HYPOGLYCEMIA IN IDDM. DIABETOLOGIA, 38, A18-A18.
Heller S, Chapman J, McCloud J & Ward J (1995) . BMJ, 310(6977), 440-440.
GEORGE E, PEACEY SR, BEDFORD C & HELLER SR (1994) HYPOGLYCEMIA ATTENUATES PHYSIOLOGICAL-RESPONSES TO FURTHER HYPOGLYCEMIA UP TO ONE, WEEK LATER. DIABETOLOGIA, 37, A165-A165.
Heller S & Ward JD (1993) Neurologic consequences of hypoglycemia and pathogenic mechanisms involved in diabetic neuropathy. Current Opinion in Neurology and Neurosurgery, 6(3), 423-428.
Heller S, Mathers N & Mackinnon M (1992) Brittle diabetes in the young. Practitioner, 236(1521), 1126-1129.
Yudkin J, Heller SR & Tattersall R (1992) . Diabetologia, 35(10), 1009-1010.
Macleod AF, Boulton AJM, Owens DR, Van Rooy P, Van Gerven JMA, Macrury S, Scarpello JHB, Segers O, Heller SR, Van Der Veen EA , Sonksen PH et al (1992) A multicentre trial of the aldose-reductase inhibitor tolrestat, in patients with symptomatic diabetic peripheral neuropathy. Diabete et Metabolisme, 18(1), 14-20.
Heller SR & Cryer PE (1991) . American Journal of Physiology-Endocrinology and Metabolism, 261(1), E41-E48.
Heller SR & MacDonald IA (1991) . Clinical Science, 81(1), 1-9.
Hirsch IB, Heller SR & Cryer PE (1991) . Clinical Science, 80(6), 583-586.
Tattersall R, Gregory R, Selby C, Kerr D & Heller S (1991) . BMJ, 302(6787), 1240-1243.
Heller SR & Cryer PE (1991) . Diabetes, 40(2), 223-226.
Heller SR & Cryer PE (1991) . Diabetes, 40(2), 223-226.
Dornan TL, Heller SR, Peck GM & Tattersal RB (1991) . Diabetes Care, 14(4), 342-344.
Kerr D, MacDonald IA, Heller SR & Tattersall RB (1990) . British Journal of Clinical Pharmacology, 29(6), 685-693.
Kerr D, Macdonald IA, Heller SR & Tattersall RB (1990) . Diabetologia, 33(4), 216-221.
Heller SR, Clarke P, Daly H, Davis I, McCulloch DK, Allison SP & Tattersall RB (1988) . Diabetic Medicine, 5(6), 552-556.
Heller SR & Tattersall RB (1987) . Diabetic Medicine, 4(3), 260-264.
Heller SR, Macdonald IA & Tattersall RB (1987) . Diabetologia, 30(12), 924-929.
Heller SR, Herbert M, Macdonald IA & Tattersall RB (1987) . The Lancet, 330(8555), 359-363.
Wilson RM (1986) . JAMA, 256(7), 877-877.
Wilson RM (1986) . JAMA: The Journal of the American Medical Association, 256(7), 877-880.
Heller SR & Hosking DJ (1986) . BMJ, 292(6520), 583-586.
Hosking DJ & Heller SR (1986) . European Journal of Clinical Pharmacology, 31(1), 27-31.
Dornan TL & Heller SR (1985) . The Lancet, 326(8448), 212-212.
Wilson RM, Minne P, Deverill I, Heller SR, Gelsthorpe K, Reeves WG & Tattersall RB (1985) . Diabetic Medicine, 2(3), 167-172.
Heller SR (1985) . Journal of Chemical Information and Modeling, 25(3), 224-231.
Baldwin N, Scott AR, Heller SR, O'Donoghue D & Tattersall RB (1985) . Diabetic Medicine, 2(5), 395-397.
Heller SR, Lowe JM, Johnson IR, O'Brien PMS, Clarke P, Symonds EM & Tattersall RB (1984) . Diabetic Medicine, 1(3), 199-204.
Heller SR, Fellows IW, Ogilvie AL & Atkinson M (1982) . BMJ, 285(6336), 167-168.
Garden GL, Fan KS, Paterson M, Shojaee-Moradie F, Borg Inguanez M, Manoli A, Edwards V, Lee V, Frier BM, Hutchison EJ , Maher D et al () . Diabetologia.
Holmes�\Truscott E, Broadley MM, S?holm U, Cooke DD, Hendrieckx C, Coates EJ, Heller SR & Speight J () . Diabetic Medicine.
S?holm U, Broadley M, Zaremba N, Divilly P, Baumann PM, Mahmoudi Z, Martine-Edith G, Mader JK, Cigler M, Br?sen JMB , Vaag A et al () . Diabetologia.
Mellor J, Kuznetsov D, Heller S, Gall M-A, Rosilio M, Amiel SA, Ibberson M, McGurnaghan S, Blackbourn L, Berthon W , Salem A et al () . Diabetologia.
Lawton J, Rankin D, Scott E, Lorencatto F, Gericke C, Heller SR & de Zoysa N () . Diabetic Medicine.
Hart RI, Rankin D, Chadwick PM, de Zoysa N, Heller S, Cooke D, Elliott J & Lawton J () . Diabetic Medicine.
Mellor J, Kuznetsov D, Heller S, Gall M-A, Rosilio M, Amiel SA, Ibberson M, McGurnaghan S, Blackbourn L, Berthon W , Salem A et al () . Diabetologia.
Carlton J, Powell PA, Broadley M, de Galan BE, Heller S, Comins J, Rosilio M, Pouwer F, Gall M-A, Child CJ , McCrimmon RJ et al () . Diabetologia.
Zaremba N, Martine�\Edith G, Divilly P, S?holm U, Broadley M, Ali N, Abbink EJ, de?Galan B, Cigler M, Mader JK , Brosen J et al () . Diabetic Medicine.
Arshad MF, Walkinshaw E, Solomon AL, Bernjak A, Rombach I, Little SA, Shaw JAM, Heller SR & Iqbal A () . Diabetic Medicine.
Lin YK, Ye W, Rogers H, Brooks A, Toschi E, Kariyawasam D, Heller S, de Zoysa N & Amiel SA () . Diabetes Technology & Therapeutics.
Martine-Edith G, Zaremba N, Divilly P, S?holm U, Broadley M, Baumann PM, Mahmoudi Z, Gomes M, Ali N, Abbink EJ , de Galan BE et al () . Diabetes Technology & Therapeutics.
Healey A, Soukup T, Sevdalis N, Bakolis I, Cross S, Heller SR, Brooks A, Kariyawasam D, Toschi E, Gonder�\Frederick L , Stadler M et al () . Diabetic Medicine.
Martine-Edith G, Divilly P, Zaremba N, S?holm U, Broadley M, Baumann PM, Mahmoudi Z, Gomes M, Ali N, Abbink EJ , de Galan BE et al () . Diabetes Technology & Therapeutics.
Fabricius TW, Verhulst CEM, Kristensen PL, Holst JJ, Tack CJ, McCrimmon RJ, Heller SR, Evans ML, de Galan BE & Pedersen-Bjergaard U () . Acta Diabetologica.
Lawton J, Chadwick PM, de Zoysa N, Stanton�\Fay S, Heller SR & Rankin D () . Diabetic Medicine.
S?holm U, Zaremba N, Broadley M, Axelsen JL, Divilly P, Martine-Edith G, Amiel SA, Mader JK, Pedersen-Bjergaard U, McCrimmon RJ , Renard E et al () . JMIR Diabetes, 8, e42100-e42100.
Bower P, Soiland�\Reyes C, Heller S, Wilson P, Cotterill S, French D & Sutton M () . Diabetic Medicine.
Garden GL, Shojaee-Moradie F, Hutchison E, Frier BM, Shaw K, Heller S, Koehler G, Mader JK, Maher D, Roberts G & Russell-Jones D () . Diabetes Technology & Therapeutics.
Ajjan RA, Heller SR, Everett CC, Vargas-Palacios A, Higham R, Sharples L, Gorog DA, Rogers A, Reynolds C, Fernandez C , Rodrigues P et al () . Diabetes Care.
Carlton J, Powell P, Rowen D, Broadley M, Pouwer F, Speight J, Heller S, Gall M, Rosilio M, Child CJ , Comins J et al () . Diabetic Medicine.
Heller S, Raposo JF, Tof�� S, Hanif W, Schroner Z, Down S & Blevins T () . Clinical Diabetes.
Verhulst CEM, Fabricius TW, Nefs G, Kessels RPC, Pouwer F, Teerenstra S, Tack CJ, Broadley MM, Kristensen PL, McCrimmon RJ , Heller S et al () . Diabetes Care.
Verhulst CEM, Fabricius TW, Teerenstra S, Kristensen PL, Tack CJ, McCrimmon RJ, Heller S, Evans ML, Amiel SA, Pedersen-Bjergaard U & de Galan BE () . Diabetologia.
Jensen MV, Broadley M, Speight J, Chatwin H, Scope A, Cantrell A, Heller S, Galan BE, Hendrieckx C & Pouwer F () . Pediatric Diabetes.
Heller SR, Geybels MS, Iqbal A, Liu L, Wagner L & Chow E () . Diabetologia.
Wylie TAF, Shah C, Burgess L, Robertson E, Dupont D, Swindell R, Hovorka R, Murphy HR & Heller SR () . Diabetic Medicine.
Holmes�\Truscott E, Cooke DD, Hendrieckx C, Coates EJ, Heller SR & Speight J () . Diabetic Medicine.
Hamilton K, Stanton�\Fay SH, Chadwick PM, Lorencatto F, de Zoysa N, Gianfrancesco C, Taylor C, Coates E, Breckenridge JP, Cooke D , Heller SR et al () . Diabetic Medicine.
Moser O, Riddell MC, Eckstein ML, Adolfsson P, Rabasa�\Lhoret R, Boom L, Gillard P, N?rgaard K, Oliver NS, Zaharieva DP , Battelino T et al () . Pediatric Diabetes.
Hendrieckx C, Gonder�\Frederick L, Heller SR, Snoek FJ & Speight J () . Diabetic Medicine.
Little SA, Speight J, Leelarathna L, Walkinshaw E, Tan HK, Bowes A, Lubina-Solomon A, Chadwick TJ, Stocken DD, Brennand C , Marshall SM et al () . Diabetes Care, dc172682-dc172682.
Heller S, Lawton J, Amiel S, Cooke D, Mansell P, Brennan A, Elliott J, Boote J, Emery C, Baird W , Basarir H et al () . Programme Grants for Applied Research, 2(5), 1-188.
Choudhary P, Geddes J, Freeman JV, Emery CJ, Heller SR & Frier BM () . Diabetic Medicine, 27(6), 666-672.
Skinner TC, Carey ME, Cradock S, Dallosso HM, Daly H, Davies MJ, Doherty Y, Heller S, Khunti K & Oliver L () . Diabetic Medicine, 27(8), 965-967.
Skinner TC, Carey ME, Cradock S, Dallosso HM, Daly H, Davies MJ, Doherty Y, Heller S, Khunti K & Oliver L () . Diabetic Medicine, 25(9), 1117-1120.
Heller S () . Diabetic Medicine, 21(9), 961-961.
Nyongesa HO, Alexakis C, Saatchi R, Rodrigues M, Harris ND, Heller SR, Davies C, Emery C & Ireland RH () . 2004 IEEE Africon. 7th Africon Conference in Africa (IEEE Cat. No.04CH37590).
Robinson RTCE, Harris ND, Ireland RH, Lindholm A & Heller SR () . British Journal of Clinical Pharmacology, 55(3), 246-251.
Garden GL, Hine JL, Mitchell SJ, Hutchison EJ, Gaffney TP, Hofmann V, Frier BM, Shaw KM, Heller SR, Koehler G , Roberts GA et al () . Diabetes Care, dc200277-dc200277.
O'Hara MC, Hynes L, O'Donnell M, Nery N, Byrne M, Heller SR, Dinneen SF & Irish Type?1 Diabetes Young Adult Study Group () . Diabet Med.
Dowey R, Iqbal A, Heller SR, Sabroe I & Prince LR () . Frontiers in Immunology, 12.
Garden GL, Frier BM, Hine JL, Hutchison EJ, Mitchell SJ, Shaw KM, Heller SR, Koehler G, Hofmann V, Gaffney TP , Maher D et al () . Diabetes, Obesity and Metabolism.
Jensen MV, Broadley M, Speight J, Scope A, Preston L, Heller S, de Galan BE, Pouwer F & Hendrieckx C () . Diabetic Medicine.
Chatwin H, Broadley M, Hendrieckx C, Carlton J, Heller S, Amiel SA, Galan BE, Hermanns N, Finke�\Groene K, Speight J & Pouwer F () . Diabetic Medicine.

Chapters

Iqbal A, Chow EYK, Jones TW & Heller SR (2024) (pp. 579-601). Wiley
Iqbal A, Chaudhury & Heller S (2024) , Metabolic Syndrome (pp. 597-608). Elsevier
Iqbal A, Chaudhury T & Heller S (2024) , Metabolic Syndrome (pp. 597-608). Elsevier
Chow EYK & Heller S (2022) , Endocrinology and Diabetes (pp. 375-386). Springer International Publishing
Chow EYK & Heller S (2014) , Endocrinology and Diabetes (pp. 429-443). Springer New York
Frier BM, Heller SR & McCrimmon RJ (2013) In Frier B, Heller S & McCrimmon R (Ed.), Hypoglycaemia in Clinical Diabetes, (pp. x-xi). Wiley
Chow E & Heller SR (2012) Pathophysiology of the effects of hypoglycemia on the cardiovascular system (pp. 3-8).
Heller SR & Tattersall RB (1983) Does diabetic control matter? (pp. 553-563).
() CRC Press
Iqbal A & Heller S () , Advanced Nutrition and Dietetics in Diabetes (pp. 60-66). John Wiley & Sons, Ltd
Chow E, Fisher M & Heller SR () , Hypoglycaemia in Clinical Diabetes (pp. 263-284). John Wiley & Sons, Ltd
Chow E & Heller SR () , Hypoglycaemia in Clinical Diabetes (pp. 96-113). John Wiley & Sons, Ltd
Heller SR () , Difficult Diabetes (pp. 168-187). Blackwell Science Ltd
Fisher M & Heller SR () , Hypoglycaemia in Clinical Diabetes (pp. 265-283). John Wiley & Sons, Ltd
Heller SR () , Hypoglycaemia in Clinical Diabetes (pp. 83-99). John Wiley & Sons, Ltd

Conference proceedings papers

SOEHOLM U, BROADLEY MM, ZAREMBA N, DIVILLY P, MARTINE-EDITH G, NEFS G, MAHMOUDI Z, MADER JK, CIGLER M, RENARD E , ABBINK EJ et al (2022) . Diabetes, Vol. 71(Supplement_1)
Pollard D, Brennan A, Coates L & Heller S (2019) . Value in Health, Vol. 22 (pp S584-S584)
Philis-Tsimikas A, Klonoff DC, Khunti K, Bajaj HS, Leiter LA, Tutkunkardas D, Troelsen LN, Bak BA, Heller SR & Pieber TR (2019) Reduced risk of hypoglycaemia and lower HbA(1c) with degludec compared to glargine U300 in insulin-treated patients with type 2 diabetes. DIABETOLOGIA, Vol. 62 (pp S47-S47)
Heller SR, Hachmann-Nielsen E & Kvist K (2019) Non-severe hypoglycaemia predicts increased risk of subsequent severe events in patients with type 2 diabetes. DIABETOLOGIA, Vol. 62 (pp S418-S418)
Gillard P, Dandona P, Mathieu C, Phillip M, Heller SR, Scheerer MF, Xu J, Thoren F, Iqbal N, Investigator D & Investigator D (2019) Analysis of patients in the dapagliflozin DEPICT-1 and-2 trials in type 1 diabetes according to HbA(1c) subgroup. DIABETOLOGIA, Vol. 62 (pp S347-S347)
Bernjak A, Heller SR & Clayton RH (2019) Can computational modelling explain the dead in bed syndrome?. DIABETOLOGIA, Vol. 62 (pp S46-S46)
Novodvorsky P, Oprescu A, Elliott J & Heller SR (2019) An audit on multidisciplinary team-lead 'Impaired Awareness of Hypoglycaemia' clinic: Outcomes, challenges and experience from ��«Ӱҵ. DIABETIC MEDICINE, Vol. 36 (pp 79-79)
Jamieson T, Heller SR, Ajjan RA & Kavanagh S (2019) Design and implementation of a hypoglycaemia toolkit for use in primary care settings. DIABETIC MEDICINE, Vol. 36 (pp 95-95)
Ali Abdelhamid Y, Bernjak A, Summers M, Weinel L, Chow E, Kar P, Phillips L, Horowitz M, Heller S & Deane A (2019) . C103. CRITICAL CARE: THE LONG WALK - ELUCIDATING OUTCOMES: DEATH, FUNCTIONAL STATUS AND COGNITION
Jaeckel E, Heller S, Bowering K, Raskin P, Liebl A, Buchholtz K, Demissie M & Pieber TR (2018) . ?Wissenschaft und klinischer Fortschritt �C gemeinsam in die Zukunft�� C www.diabeteskongress.de, 9 May 2018 - 12 May 2018.
Bernjak A, Chow E, Lee J, Iqbal A, Lubina-Solomon A, Walkinshaw E, Macdonald IA, Heller SR, Clayton RH & Sheridan PJ (2017) Pharmacological autonomic blockade during experimental hypoglycaemia exacerbates cardiac repolarisation abnormalities. DIABETOLOGIA, Vol. 60 (pp S74-S74)
Novodvorsky P, Bernjak A, Chow E, Iqbal A, Sellors L, Williams S, Fawdry RA, Jacques RM, Sheridan PJ & Heller SR (2017) Risk of cardiac arrhythmias and electrophysiological responses during spontaneous hyperglycaemia in young people with type 1 diabetes. DIABETOLOGIA, Vol. 60 (pp S534-S534)
Speight J, Holmes-Truscott E, Kerr D, Flanagan D, Heller SR, Evans ML & Shaw JAM (2017) Satisfaction with insulin delivery and glucose monitoring modalities among adults with long-standing Type 1 diabetes and problematic hypoglycaemia: results from the HypoCOMPaSS study. DIABETIC MEDICINE, Vol. 34 (pp 30-30)
Holmes-Truscott E, Speight J, Kerr D, Flanagan D, Heller SR, Evans ML & Shaw JAM (2017) Sustained improvement in diabetes-specific quality of life in adults with long-standing Type 1 diabetes and problematic hypoglycaemia: two year results from the HypoCOMPaSS study. DIABETIC MEDICINE, Vol. 34 (pp 13-13)
Russell�\Jones D, Heller SR, Buchs S, Sandberg A, Valentine WJ & Hunt B (2017) . Diabetes, Obesity and Metabolism, Vol. 19(12) (pp 1773-1780)
Lloyd AJ, Meneghini L, Kragh N, Nikolajsen A, Lewis HB & Heller SR (2016) Psychometric properties of a new scale assessing the impact of acute postprandial hyperglycaemia: the aPPHG-Q. QUALITY OF LIFE RESEARCH, Vol. 25 (pp 132-133)
Sinclair A, Heller SR, Pratley RE, Weitgasser R, Festa A, Kiljanski J, Brusko CS, Duan R & Heine RJ (2016) Comparison of two treatment approaches in older patients with type 2 diabetes (IMPERIUM). DIABETOLOGIA, Vol. 59 (pp S395-S396)
Korsatko S, Brunner M, Sach-Friedl S, Jensen L, Tarp M, Holst AG, Heller SR & Pieber TR (2016) Effect of once-weekly semaglutide on the counter-regulatory response to hypoglycaemia in subjects with type 2 diabetes. DIABETOLOGIA, Vol. 59 (pp S363-S364)
Heller SR, Bergenstal R, Cannon CP, Kupfer S, Wilson C, White WB & Investigators EXAMINE (2016) Hypoglycaemia is associated with increased risk of cardiovascular events: results from the EXAMINE trial. DIABETOLOGIA, Vol. 59 (pp S44-S44)
Kar P, Plummer MP, Giersch E, Summers MJ, Hatzinikolas S, Horowitz M, Chapman MJ, Jones KL, Heller SR & Deane A (2016) Effects of antecedent hypoglycaemia on gastric and cardiac responses to subsequent hypoglycaemia in health. DIABETOLOGIA, Vol. 59 (pp S405-S405)
Walkinshaw E, Little SA, Bernjak A, Lubina-Solomon A, Chow E, Shaw JAM & Heller SR (2015) Cardiac autonomic regulation during experimental hypoglycaemia in type 1 diabetes with impaired awareness of hypoglycaemia. DIABETOLOGIA, Vol. 58 (pp S63-S63)
White WB, Wilson CA, Bakris GL, Bergenstal RM, Cannon CP, Cushman WC, Fleck PR, Heller SR, Kupfer S, Mehta CR , Menon V et al (2015) Major cardiovascular outcomes in the EXAMINE trial according to ACE inhibitor use. DIABETOLOGIA, Vol. 58 (pp S395-S396)
Tan HK, Little SA, Leelarathna L, Walkinshaw E, Lubina-Solomon A, Kerr D, Heller SR, Evans ML, Shaw JA, Flanagan D & Speight J (2015) Hypoglycaemia avoidance training improves glucose variability in Type 1 diabetes (HypoCOMPaSS Study). DIABETIC MEDICINE, Vol. 32 (pp 7-7)
Heller SR, Mathieu C, Kapur R, Wolden ML & Zinman B (2015) Nocturnal confirmed hypoglycaemia with insulin degludec vs insulin glargine: rate ratios for different definitions. DIABETIC MEDICINE, Vol. 32 (pp 67-67)
Speight J, Singh H, Little SA, Flanagan D, Kerr D, Evans ML, Heller SR & Shaw JA (2015) Associations with hyperglycaemia avoidance among adults with long-standing Type 1 diabetes and impaired awareness of hypoglycaemia: baseline characteristics from the HypoCOMPaSS Study. DIABETIC MEDICINE, Vol. 32 (pp 186-186)
Sellors L, Parekh B, Bernjak A, Chow E, Sheridan P & Heller SR (2015) Effect of sleep on cardiac autonomic tone during nocturnal hypoglycaemia in adults with Type 1 diabetes. DIABETIC MEDICINE, Vol. 32 (pp 21-21)
Walkinshaw E, Little SA, Bernjak A, Lubina-Solomon A, Chow E, Shaw JA & Heller SR (2015) Cardiac autonomic regulation during experimental hypoglycaemia in Type 1 diabetes with impaired awareness of hypoglycaemia (IAH). DIABETIC MEDICINE, Vol. 32 (pp 61-61)
Thabit H, Elleri D, Leelarathna L, Allen J, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska M , Barnard K et al (2015) . The Lancet, Vol. 385 (pp S96-S96)
Tauschmann M, Thabit H, Elleri D, Lubina-Solomon A, Stadler M, Heller SR, Amiel SA, Evans ML, Dunger DB & Hovorka R (2015) PERFORMANCE DURING UNSUPERVISED CLOSED LOOP IN CHILDREN AND ADULTS WITH TYPE 1 DIABETES: WHAT MAKES THE DIFFERENCE?. DIABETES TECHNOLOGY & THERAPEUTICS, Vol. 17 (pp A100-A101)
Leelarathna L, Thabit H, Elleri D, Allen JM, Lubina-Solomon A, Mader JK, Benesch C, Stadler M, Pieber TR, Arnolds S , Heller SR et al (2014) Accuracy of Continuous Glucose Monitoring (CGM) under free-living conditions during three home closed loop studies. DIABETOLOGIA, Vol. 57 (pp S406-S407)
White WB, Heller SR, Bergenstal RM, Wilson C & Oh R (2014) Effects of baseline glycaemic HbA1c on CV outcomes and blood glucose control during the EXAMINE trial in patients with type 2 diabetes and recent acute coronary syndrome. DIABETOLOGIA, Vol. 57 (pp S357-S357)
Tauschmann M, Thabit H, Leelarathna L, Elleri D, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P , Heller SR et al (2014) Factors predictive of overnight closed loop performance during free living in children and adults with type 1 diabetes. DIABETOLOGIA, Vol. 57 (pp S414-S414)
Heller SR, Frier BM, Herslov ML, Gundgaard J & Gough S (2014) Severe hypoglycaemia often results in hospital visits and ambulance calls regardless of insulin regimen. DIABETOLOGIA, Vol. 57 (pp S204-S204)
Chow E, Bernjak A, Sheridan PJ & Heller SR (2014) Cardiac autonomic regulation during acute experimental hypoglycaemia in type 2 diabetes. DIABETOLOGIA, Vol. 57 (pp S260-S261)
Habit H, Leelarathna L, Elleri D, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska ME , Heller SR et al (2014) Three to four weeks of overnight closed loop insulin delivery during free living: analysis of randomised crossover studies in adults and adolescents with type 1 diabetes. DIABETOLOGIA, Vol. 57 (pp S89-S89)
Thabit H, Hovorka R, Walkinshaw E, Lubina-Solomon A, Stadler M, Tinati T, Heller SR, Amiel SA, Evans ML & Barnard KD (2014) Psychosocial impact of closed loop therapy for adults with Type 1 diabetes: overnight closed loop at home study. DIABETIC MEDICINE, Vol. 31 (pp 151-151)
Chow E, Iqbal A, Bernjak A, Ajjan R & Heller SR (2014) . The Lancet, Vol. 383 (pp S35-S35)
Barnard KD, Thabit H, Walkinshaw E, Lubina-Solomon A, Stadler M, Tinati T, Heller SR, Amiel SA, Evans M & Hovorka R (2014) PSYCHOSOCIAL IMPACT OF CLOSED LOOP THERAPY - ADULTS WITH TYPE 1 DIABETES: OVERNIGHT CLOSED LOOP AT HOME STUDY. DIABETES TECHNOLOGY & THERAPEUTICS, Vol. 16 (pp A102-A102)
Heller SR, Korsatko S, Gurban J, Jensen L, Christiansen E, Kiyomi F & Pieber TR (2013) Positive effects of liraglutide as adjunct to insulin in type 1 diabetes: glycaemic control and safety in a randomised, double blind, placebo controlled crossover trial. DIABETOLOGIA, Vol. 56 (pp S7-S8)
Pieber TR, Deller S, Brunner M, Jensen L, Christiansen E, Kiyomi F & Heller SR (2013) Treatment with liraglutide as adjunct to insulin in type 1 diabetes; effects on counter regulatory response to hypoglycaemia: a randomised, double blind, crossover trial. DIABETOLOGIA, Vol. 56 (pp S404-S405)
O' Hara M, Byrne M, Lawton J, Mueller U, Mueller N, Zillich F, Mansell P, Lawrence I, Heller SR, Dinneen SF , O' Shea E et al (2013) A cross country qualitative investigation of structured education programmes for adults with type 1 diabetes. DIABETOLOGIA, Vol. 56 (pp S452-S453)
Bernjak A, Chow EYK, Walkinshaw E, Lubina-Solomon A, Sheridan PJ & Heller SR (2013) Experimental hypoglycaemia decreases cardiac vagal function for between 7 to 30 days in patients with type 2 diabetes. DIABETOLOGIA, Vol. 56 (pp S243-S243)
Chow EYK, Iqbal A, Phoenix F, Heller SR & Ajjan R (2013) Hypoglycaemia promotes thrombosis and inflammation for at least one week in patients with type 2 diabetes. DIABETOLOGIA, Vol. 56 (pp S243-S243)
Choudhary P, Davies C, Emery CJ & Heller SR (2013) . Diabetic Medicine, Vol. 30(8) (pp 914-917)
Heller SR, Pieber T, Korsatko S, Kohler G, Deller S, Bock G, Zahiragic S, Mader J, Roepstorff C, Rasmussen S & Haahr H (2011) A higher counter-regulatory hormone response is seen with insulin degludec than insulin glargine in response to induced hypoglycaemia in type 1 diabetes. DIABETOLOGIA, Vol. 54 (pp S261-S261)
Russell-Jones DL, Francisco AO, Pei H & Heller SR (2011) Basal-bolus therapy with insulin degludec improves long-term glycaemic control with less nocturnal hypoglycaemia compared with insulin. DIABETOLOGIA, Vol. 54 (pp S425-S425)
Heller S (2011) Impaired awareness of hypoglycemia: Commentary. Diabetic Hypoglycemia, Vol. 3(3) (pp 9)
Kumareswaran K, Elleri D, Allen JM, Harris J, Xing D, Kollman C, Nodale M, Murphy HR, Amiel SA, Heller SR , Wilinska ME et al (2011) . Journal of Diabetes Science and Technology, Vol. 5(6) (pp 1352-1362)
Heller S (2010) Hypoglycemia and clinical islet transplantation. Diabetic Hypoglycemia, Vol. 3(2) (pp 11-12)
De Galan BE, Zoungas S, Patel A, Li Q, Billot L, Woodward M, Chalmers J, Neal B, MacMahon S, Grobbee D & Heller SR (2010) Nature of association between severe hypoglycaemia and risks of vascular events and death in ADVANCE. DIABETOLOGIA, Vol. 53
Kumareswaran K, Harris J, Elleri D, Allen JM, Nodale M, Wilinska ME, Dunger DB, Amiel SA, Heller SR, Evans ML & Hovorka R (2010) Overnight closed-loop glucose control following consumption of alcohol in adults with type 1 diabetes. DIABETOLOGIA, Vol. 53 (pp S25-S26)
Heller S (2007) . Diabetes Research and Clinical Practice, Vol. 78(3) (pp S40-S46)
Choudhary P, Emery CJ & Heller SR (2007) Do high fasting glucose levels suggest nocturnal hypoglycaemia? The Somogyi effect - fact or fiction?. DIABETOLOGIA, Vol. 50 (pp S335-S336)
Hansen MV, Pedersen-Bjergaard U, Heller SR, Wallace TM, Rasmussen AK, Jorgensen HV, Matthews DR, Hougaard P, Pramming S & Thorsteinsson B (2006) Frequency and motives of blood glucose self-monitoring in type I diabetes: association with glycaemic control, complications, and patient characteristics. DIABETOLOGIA, Vol. 49 (pp 494-494)
Heller SR, Mathiesen E, Kinsley B, McCance D, Duran S, Bellaire S & Raben A (2006) Maternal hypoglycaemia and glycaemic control in pregnancy: a randomised trial comparing insulin aspart with human insulin in 322 subjects with type 1 diabetes. DIABETOLOGIA, Vol. 49 (pp 576-577)
Choudhary P, Davies CM, Emery CJ, Freeman JV & Heller SR (2006) Sensitivity and specificity of CGMS for identifying clinially relevant symptomatic hypoglycaemia. DIABETOLOGIA, Vol. 49 (pp 507-508)
Ashwell SG, Amiel SA, Bilous RW, Dashora U, Heller SR, Hepburn DA, Shutler SD, Stephens JW & Home PD (2006) . Diabetic Medicine, Vol. 23(3) (pp 285-292)
Alexakis C, Nyongesa HO, Saatchi R, Harris ND, Davies C, Emery C, Ireland RH & Heller SR (2003) . Computers in Cardiology, 2003, 24 September 2003 - 24 September 2003.
Lee SP, Robinson RT, Harris ND, Davies CM, Cunningham M, Hudson S, Macdonald IA & Heller SR (2002) Effect of atenolol on QTc interval lengthening during hypoglycaemia in Type 1 diabetes. DIABETOLOGIA, Vol. 45 (pp A78-A78)
RostamiHodjegan A, Peacey SR, Heller SR & Tucker GT (1996) A pharmacokinetic-pharmacodynamic model to explain the biphasic insulinergic effect of tolbutamide and the suppressive role of lowering blood glucose on this effect. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol. 42(5) (pp P675-P676)
Kruger J, Brennan A, Thokala P, Fitzgerald P & Heller S ()
Harris ND, Ireland RH, Marques JLB, Hudson S, Davies C, Lee S, Robinson RT & Heller SR () . Computers in Cardiology 2000. Vol.27 (Cat. 00CH37163)
Ireland RH, Robinson RTCE, Heller SR & Harris ND () . Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)

Reports

Heller S, Darp? B, Mitchell MI, Linnebjerg H, Leishman DJ, Mehrotra N, Zhu H, Koerner J, Fiszman ML, Balakrishnan S , Xiao S et al (2015)
Seaquist ER, Anderson J, Childs B, Cryer P, Dagogo-Jack S, Fish L, Heller SR, Rodriguez H, Rosenzweig J & Vigersky R (2013)
Seaquist ER, Anderson J, Childs B, Cryer P, Dagogo-Jack S, Fish L, Heller SR, Rodriguez H, Rosenzweig J & Vigersky R (2013)
Forbes A, While A, Griffiths P, Ismail K & Heller S (2011)

Posters

Basarir H, Kruger J, Brennan A, Thokala P, Jacques R, Dixon S, Elliott J, Heller S & Mansell P The Cost-Effectiveness of 5-week versus 1-week DAFNE Structured Education in Type 1 Diabetes: A Preliminary Evaluation Using the ��«Ӱҵ Type 1 Diabetes Policy Model (Diabetes UK Professional Conference 13-15 March 2013).
Kruger J, Brennan A, Thokala P, Basarir H & Heller S The Cost-Effectiveness of Dose Adjustment For Normal Eating (DAFNE) Structured Education in Type 1 Diabetes: An Update using the ��«Ӱҵ Type 1 Diabetes Policy Model (Diabetes UK Professional Conference 13-15 March 2013).

Other

Carlton J, Leaviss J, Pouwer F, Hendrieckx C, Broadley MM, Clowes M, McCrimmon RJ, Heller SR & Speight J (2022) . Diabetologia.
Campbell M, Heller SR & Jacques RM (2018) . Diabetes Care, 41(4), e65-e66.
Little SA, Leelarathna L, Walkinshaw E, Kai Tan H, Chapple O, Lubina-Solomon A, Chadwick TJ, Barendse S, Stocken DD, Brennand C , Marshall SM et al (2014) . Diabetes Care, 37(12), e272-e273.
Hattersley AT, Marcovecchio ML, Chiarelli F, Silverstein J, Heller S, Damm P, Mathiesen ER, Zinman B & Sinclair A (2014) . The Lancet Diabetes & Endocrinology, 2(3), 194-195.
Heller SR (2014) . Diabetologia, 57(5), 847-849.
Barnard KD, Campbell MJ, Emery C, Young AJ & Heller S (2012) . Diabetic Medicine, 29(12), 1600-1601.
Heller S, McCance DR, Moghissi E, Nazeri A & Kordonouri O (2012) . Diabetes/Metabolism Research and Reviews, 28(1), 50-61.
Elliott J & Heller S (2011) . Practical Diabetes International, 28(5), 227-232.
Heller SR (2011) . The British Journal of Diabetes & Vascular Disease, 11(1_suppl), 6-9.
Heller S (2010) . Medicine, 38(12), 671-675.
Heller S (2010) Self-destructive behavior - A case of recurrent severe hypoglycemia. Diabetic Hypoglycemia, 2(3), 17-18.

Preprints

Breckenridge J, Gossage-Worrall R, Chadwick P, de Zoysa N, Elliott J, Gianfrancesco C, Hamilton K, Heller S, Lawton J, Rankin D , Stanton-Fay S et al (2024) , Research Square Platform LLC.
Leavy OC, Russell RJ, Harrison EM, Lone NI, Kerr S, Docherty AB, Sheikh A, Richardson M, Elneima O, Greening NJ , Harris VC et al (2023) , Cold Spring Harbor Laboratory.
Elneima O, McAuley HJC, Leavy OC, Chalmers JD, Horsley A, Ho L-P, Marks M, Poinasamy K, Raman B, Shikotra A , Singapuri A et al (2023) , Cold Spring Harbor Laboratory.
Evans RA, McAuley H, Harrison EM, Shikotra A, Singapuri A, Sereno M, Elneima O, Docherty AB, Lone NI, Leavy OC , Daines L et al () , Cold Spring Harbor Laboratory.

Grants

National Institute of Health Research, Programme Grant October 2007-April 2013. Improving management of Type 1 diabetes in the UK: the DAFNE programme as a research test-bed. Principal

Investigator in collaboration with Dr J Lawton, Dr M Clarke, Ms G Thompson, Prof S Amiel, Prof M Campbell, Dr P Mansell, Dr I Lawrence, Ms C Taylor, Ms L Oliver (Chief Investigator) ?1.8m

Diabetes UK. Jan 2009-July 2013. KICk-OFF: A multi-centre, randomised controlled trial comparing intensive structured education with standard education in 11-16 year olds on intensive insulin therapy.

Dr K Price, Prof C Eiser Dr J Wales, Dr J Freeman (co-investigator) ?1.35m

Diabetes UK. April 2008-March 2011. Overnight hypoglycaemia prevention in adult subjects with type 1 diabetes: Closing the loop

Dr R Hovorka, Prof S Amiel Dr M Evans, (co-investigator) ?750k

Diabetes UK. Sep 2009-March 2012. Prevention of recurrent severe hypoglycaemia: a definitive RCT comparing optimised MDI and CSII with or without adjunctive real-time continuous glucose monitoring

Dr J Shaw, Prof D Kerr, Dr D Flanagan, Dr M Evans, Dr J Speight (co-investigator) ?1.4m

South Yorkshire Research Collaborations for Leadership in Applied Health Research and Care October 2008- September 2013 Diabetes Theme Adolescent Project to develop a structured training programme and other interventions to improve outcomes in young people with Type 1 diabetes aged 16-21years.

Prof C Eiser, Dr A Scott, (Chief Investigator) ?900k

Health Technology Assessment Grant. June 2011-Dec 2015 The REPOSE (Relative Effectiveness of Pumps Or Structured Education) Trial.

Prof N Waugh, Dr C Cooper, Prof M Campbell, Prof S Amiel, Dr P Hammond, Ms C Taylor, Dr R Lindsay, Dr J Lawton, Dr K Barnard, Dr M Evans, Dr F Green, Dr A Jaap, Ms C Taylor, Prof S Dixon, (Chief Investigator). ?2.0m

Health Technology Assessment Grant. 14/213/10 January 2016 �C June 2017 A systematic review of psychological interventions to improve motivation for self-management in people with type 1 and type 2 diabetes

Dr K Winkley, Prof Khalida Ismail, Prof A Brennan (co-investigator) ?176.74k

National Institute of Health Research, Programme Grant March 2016- September 2021. Developing and trialling the DAFNEplus (Dose for Adjustment for Normal Eating) intervention. A lifelong approach to promote effective self-management in adults with type 1 diabetes.

Chief Investigator in collaboration with Professor J Lawton, Professor S Michie, Ms G Thompson, Prof S Amiel, Prof M Campbell, Dr P Mansell, Dr D Hopkins, Ms C Taylor, Dr J Elliott, Mr S Fisher, Prof L Yardley, Prof A Brennan, Dr J Cohen, Dr D Cooke, Prof W Baird. (Chief Investigator) ?2.75m

Professional activities and memberships

Activities and Distinctions

Diabetes UK Research Committee 2005 �C 2015. Professional Advisory Council 2003-2008. Scientific and Research Advisory Group. 2009- present, Arnold Bloom Lecture, Diabetes UK, 2012
Member of NICE/RCP working groups developing national guidelines for the management of adult Type 1 (2002) and Type 2 diabetes (2000).
Deputy Chair Joint DoH/MRC Research Advisory Committee on Diabetes 2002
Member of MRC College of Experts 2005-2009
Acting Portfolio Director in Diabetes, Dept of Health, Sept �C Dec 2004
I chaired the Clinical Studies Advisory Group (2008-2014) and sit on the Management Committee of the UK Diabetes Clinical Research Network. I am currently the acting National Speciality Lead for Diabetes in the NIHR Clinical Research Network.
NIHR Senior Investigator (since 2012)
Regional Diabetes Specialty Lead, Yorks/Humber CRN, 2014 to present
National Diabetes Speciality Lead, NIHR CRN, 2015 to present