Professor Stephen B Wharton

Neuroscience, School of Medicine and Population Health

Professor and Honorary Consultant in Neuropathology

Steve Wharton
Profile picture of Steve Wharton
s.wharton@sheffield.ac.uk

Full contact details

Professor Stephen B Wharton
Neuroscience, School of Medicine and Population Health
葫芦影业 Institute for Translational Neuroscience (SITraN)
385a Glossop Road
葫芦影业
S10 2HQ
Profile
  • 2014 - present: Professor in Neuropathology, 葫芦影业
  • 2001-2014:  Senior Lecturer / Reader in Neuropathology, 葫芦影业
  • 2001 鈥 present: honorary consultant in neuropathology, 葫芦影业 Teaching Hospitals
  • 1997 - 2001: Senior lecturer / honorary consultant in Neuropathology, Edinburgh University
  • 1994 鈥 1997: Senior registrar in Neuropathology, Addenbrookes Hospital, Cambridge
Qualifications
  • PhD, University of 葫芦影业, 2013
  • FRCPath awarded 2005
  • MRCPath in Neuropathology 1997
  • DipRCPath Histopathology 1995
  • MSc University of Cambridge 1995
  • MBBS London University 1988
  • BSc (Hons) University of London 1985
Research interests

Professor Wharton鈥檚 research interest are focused on the cellular and molecular pathology of dementia and brain ageing. His major areas of interest are in:

  • Lead in neuropathology for the which takes a population-based approach to understanding the pathological basis of late-life dementia.
  • Investigating the cellular and molecular pathology of astrocytes, neurones and endothelium as components of the neurovascular unit in brain ageing and in the pathogenesis of dementia.
  • The pathogenesis of white matter pathology in brain ageing and its contribution to dementia.
  • The pathology of motor neurone diseases and tissue banking.

External collaborations

  • Prof Fiona Matthews (University of Newcastle) and Prof Carol Brayne (University of Cambridge). The Cognitive Function and Ageing Study.
Publications

Journal articles

  • Xia Z, Prescott EE, Urbanek A, Wareing HE, King MC, Olerinyova A, Dakin H, Leah T, Barnes KA, Matuszyk MM , Dimou E et al (2024) . Nature Communications, 15. RIS download Bibtex download
  • Floare M-L, Wharton SB, Simpson JE, Aeschlimann D, Hoggard N & Hadjivassiliou M (2024) . Brain Communications, 6(2). RIS download Bibtex download
  • Rajab MD, Taketa T, Wharton SB, Wang D & Cognitive Function and Ageing Neuropathology Study, and for the (2024) . Brain Pathol, e13247. RIS download Bibtex download
  • Mistry H, Richardson CD, Higginbottom A, Ashford B, Ahamed SU, Moore Z, Matthews FE, Brayne C, Simpson JE & Wharton SB (2024) . Neuroscience Research. RIS download Bibtex download
  • Sanders MI, Gatt D, Lee V, Wharton SB & Bagga V (2024) . Brain and Spine, 4, 102819-102819. RIS download Bibtex download
  • Rajab MD, Jammeh E, Taketa T, Brayne C, Matthews FE, Su L, Ince PG, Wharton SB & Wang D (2023) . Alzheimer鈥檚 Research & Therapy, 15. RIS download Bibtex download
  • Nichols E, Merrick R, Hay SI, Himali D, Himali JJ, Hunter S, Keage HAD, Latimer CS, Scott MR, Steinmetz JD , Walker JM et al (2023) . The Lancet Healthy Longevity, 4(3), e115-e125. RIS download Bibtex download
  • Nichols E, Merrick R, Wharton S, Matthews FE, Brayne C & Vos T (2022) . Alzheimer's & Dementia, 18(S5). RIS download Bibtex download
  • Williamson D, Schwalbe EC, Hicks D, Aldinger KA, Lindsey JC, Crosier S, Richardson S, Goddard J, Hill RM, Castle J , Grabovska Y et al (2022) . Cell Reports, 40(5), 111162-111162. RIS download Bibtex download
  • Hase Y, Ameen鈥怉li KE, Waller R, Simpson JE, Stafford C, Mahesh A, Ryan L, Pickering L, Bodman C, Hase M , Boche D et al (2022) . Brain Pathology. RIS download Bibtex download
  • Nelson PT, Brayne C, Flanagan ME, Abner EL, Agrawal S, Attems J, Castellani RJ, Corrada MM, Cykowski MD, Di J , Dickson DW et al (2022) . Acta Neuropathologica, 144(1), 27-44. RIS download Bibtex download
  • Waller R, Hase Y, Simpson JE, Heath PR, Wyles M, Kalaria RN & Wharton SB (2022) . Translational Stroke Research. RIS download Bibtex download
  • Perez-Nievas BG, Johnson L, Beltran-Lobo P, Hughes MM, Gammallieri L, Tarsitano F, Myszczynska MA, Vazquez-Villasenor I, Jimenez-Sanchez M, Troakes C , Wharton SB et al (2021) . Journal of Neuroinflammation, 18(1). RIS download Bibtex download
  • Matuszyk MM, Garwood CJ, Ferraiuolo L, Simpson JE, Staniforth RA & Wharton SB (2021) . Journal of Neurochemistry. RIS download Bibtex download
  • Ellmerich S, Taylor GW, Richardson CD, Minett T, Schmidt AF, Brayne C, Matthews FE, Ince PG, Wharton SB & Pepys MB (2021) . Brain Communications, 3(4). RIS download Bibtex download
  • Vazquez鈥怴illasenor I, Garwood CJ, Simpson JE, Heath PR, Mortiboys H & Wharton SB (2021) . European Journal of Neuroscience. RIS download Bibtex download
  • Waller R, Narramore R, Simpson JE, Heath PR, Verma N, Tinsley M, Barnes J, Haris H, Henderson FE, Matthews FE , Richardson CD et al (2021) . Brain Pathology, 31(3). RIS download Bibtex download
  • Crosier S, Hicks D, Schwalbe EC, Williamson D, Nicholson SL, Smith A, Lindsey JC, Michalski A, Pizer B, Bailey S , Bown N et al (2021) . Neuropathol Appl Neurobiol. RIS download Bibtex download
  • Dodds RM, Murray JC, Granic A, Hurst C, Uwimpuhwe G, Richardson S, Brayne C, Matthews FE & Sayer AA (2021) . Journal of Cachexia, Sarcopenia and Muscle, 12(2), 308-318. RIS download Bibtex download
  • Bury JJ, Chambers A, Heath PR, Ince PG, Shaw PJ, Matthews FE, Brayne C, Simpson JE & Wharton SB (2021) . Acta Neuropathologica Communications, 9(1). RIS download Bibtex download
  • Leah T, Vazquez-Villase帽or I, Ferraiuolo L, Wharton S & Mortiboys H (2021) . Bio-protocol, 11(1). RIS download Bibtex download
  • Richardson S, Hill RM, Kui C, Lindsey JC, Grabovska Y, Schwalbe EC, Hicks D, Williamson D, Crosier S, Joshi A , Wharton SB et al (2020) . Neuro-Oncology, 22(Supplement_3), iii408-iii408. RIS download Bibtex download
  • Hill R, Richardson S, Schwalbe E, Hicks D, Lindsey J, Crosier S, Rafiee G, Grabovska Y, Wharton S, Jacques T , Michalski A et al (2020) . Neuro-Oncology, 22(Supplement_3), iii405-iii406. RIS download Bibtex download
  • De Marco M, Manca R, Kirby J, Hautbergue G, Blackburn DJ, Wharton S & Venneri A (2020) . Alzheimer's & Dementia, 16(S4). RIS download Bibtex download
  • Richardson S, Hill RM, Kui C, Lindsey JC, Grabovska Y, Schwalbe EC, Hicks D, Williamson D, Crosier S, Joshi A , Wharton SB et al (2020) MBRS-60. THE ACTIONABLE GENOMIC LANDSCAPE OF RELAPSED MEDULLOBLASTOMA IS DEFINED BY MAINTENANCE AND ACQUISITION OF DRIVER EVENTS. Neuro-oncology, 22(Suppl 3), iii408-iii408. RIS download Bibtex download
  • Hill R, Richardson S, Schwalbe E, Hicks D, Lindsey J, Crosier S, Rafiee G, Grabovska Y, Wharton S, Jacques T , Michalski A et al (2020) MBRS-44. TIME, PATTERN AND OUTCOME OF MEDULLOBLASTOMA RELAPSE ARE ASSOCIATED WITH TUMOUR BIOLOGY AT DIAGNOSIS AND UPFRONT THERAPY: A COHORT STUDY. Neuro-oncology, 22(Suppl 3), iii405-iii406. RIS download Bibtex download
  • Allen SP, Seehra RS, Heath PR, Hall BPC, Bates J, Garwood CJ, Matuszyk MM, Wharton SB & Simpson JE (2020) . International Journal of Molecular Sciences, 21(21). RIS download Bibtex download
  • Fadul MM, Heath PR, Cooper-Knock J, Kurz JM, Al-Azzawi HA, Ali Z, Smith T, Matthews FE, Brayne C, Wharton SB & Simpson JE (2020) . International Journal of Molecular Sciences, 21(21). RIS download Bibtex download
  • Hill RM, Richardson S, Schwalbe EC, Hicks D, Lindsey JC, Crosier S, Rafiee G, Grabovska Y, Wharton SB, Jacques TS , Michalski A et al (2020) . The Lancet Child & Adolescent Health. RIS download Bibtex download
  • De Marco M, Manca R, Kirby J, Hautbergue GM, Blackburn DJ, Wharton SB & Venneri A (2020) . Current Alzheimer Research, 17. RIS download Bibtex download
  • Hicks D, Rafiee G, Schwalbe EC, Howell CI, Lindsey JC, Hill RM, Smith AJ, Adidharma P, Steel C, Richardson S , Pease L et al (2020) . Neuropathology and Applied Neurobiology. RIS download Bibtex download
  • MacGregor Sharp M, Saito S, Keable A, Gatherer M, Aldea R, Agarwal N, Simpson JE, Wharton SB, Weller RO & Carare RO (2020) . Acta Neuropathologica Communications, 8(1). RIS download Bibtex download
  • Chambers A, Bury JJ, Minett T, Richardson CD, Brayne C, Ince PG, Shaw PJ, Garwood CJ, Heath PR, Simpson JE , Matthews FE et al (2020) . Journal of Neuropathology & Experimental Neurology, 79(9), 950-958. RIS download Bibtex download
  • Shabir O, Sharp P, Rebollar MA, Boorman L, Howarth C, Wharton SB, Francis SE & Berwick J (2020) . Scientific Reports, 10(1). RIS download Bibtex download
  • Das J, Gill A, Lo C, Chan-Lam N, Price S, Wharton SB, Jessop H, Sharrack B & Snowden JA (2020) . Frontiers in Immunology, 11. RIS download Bibtex download
  • Waller R, Mandeya M, Viney E, Simpson JE & Wharton SB (2020) . Neuropathology. RIS download Bibtex download
  • Richardson K, Wharton SB, Grossi CM, Matthews FE, Fox C, Maidment I, Loke YK, Steel N, Arthur A, Myint PK , Boustani M et al (2020) . Journal of Alzheimer's Disease. RIS download Bibtex download
  • Fadul MM, Garwood CJ, Waller R, Garrett N, Heath PR, Matthews FE, Brayne C, Wharton SB & Simpson JE (2020) . International Journal of Molecular Sciences, 21(1). RIS download Bibtex download
  • Arthur A, Savva GM, Barnes LE, Borjian-Boroojeny A, Dening T, Jagger C, Matthews FE, Robinson L & Brayne C (2020) . The British Journal of Psychiatry, 216(1), 49-54. RIS download Bibtex download
  • Wharton SB, Wang D, Parikh C, Matthews FE, Brayne C & Ince PG (2019) . Acta Neuropathologica Communications, 7(1), 1-12. RIS download Bibtex download
  • Sharp P, Ameen-Ali K, Boorman L, Harris S, Wharton S, Howarth C, Shabir O, Redgrave P & Berwick J (2019) . Journal of Cerebral Blood Flow and Metabolism. RIS download Bibtex download
  • Ajikumar A, Long MB, Heath PR, Wharton SB, Ince PG, Ridger VC & Simpson JE (2019) . International Journal of Molecular Sciences, 20(20). RIS download Bibtex download
  • Fox C, Richardson K, Savva GM, Robinson L, Maidment ID, Loke Y, Brayne C, Mathews F, Ince P, Wharton S , Myint P et al (2019) . Alzheimer's & Dementia, 15, P1232-P1232. RIS download Bibtex download
  • Goodall EF, Leach V, Wang C, Cooper-Knock J, Heath PR, Baker D, Drew DR, Saffrey MJ, Simpson JE, Romero IA & Wharton SB (2019) . International Journal of Molecular Sciences, 20(12). RIS download Bibtex download
  • Vazquez鈥怴illase帽or I, Garwood CJ, Heath PR, Simpson JE, Ince PG & Wharton SB (2019) . Neuropathology and Applied Neurobiology. RIS download Bibtex download
  • Ameen-Ali K, Simpson J, Wharton S, Heath P, Sharp P, Brezzo G & Berwick J (2019) . Journal of Alzheimer's disease : JAD. RIS download Bibtex download
  • Wharton SB, Verber NS, Wagner BE, Highley JR, Fillingham DJ, Waller R, Strand K, Ince PG & Shaw PJ (2019) . Neuropathology and Applied Neurobiology. RIS download Bibtex download
  • Waller R, Murphy M, Garwood C, Jennings L, Heath P, Chambers A, Matthews F, Brayne C, Ince P, Wharton S & Simpson J (2018) . Glia, 66(11), 2316-2323. RIS download Bibtex download
  • Mills MT, Wharton SB, Connolly DJ, Mirza S & Sinha S (2018) . British Journal of Neurosurgery. RIS download Bibtex download
  • Ratcliffe LE, V谩zquez Villase帽or I, Jennings L, Heath PR, Mortiboys H, Schwartzentruber A, Karyka E, Simpson JE, Ince PG, Garwood CJ & Wharton SB (2018) . Neuroscience, 390, 46-59. RIS download Bibtex download
  • Morgan SV, Garwood CJ, Jennings L, Simpson JE, Castelli LM, Heath PR, Mihaylov SR, Vaqu茅z-Villase帽or I, Minshull TC, Ince PG , Dickman MJ et al (2018) . European Journal of Neuroscience, 47(12), 1444-1456. RIS download Bibtex download
  • Simpson JE, Wharton S, Brayne C, Matthews F, Heath P & Ince P (2018) . Alzheimer's & Dementia, 14(7S_Part_31), P1624-P1624. RIS download Bibtex download
  • Ajikumar A, Ridger V, Heath P, Wharton S, Ince P & Simpson JE (2018) . Alzheimer's & Dementia, 14(7S_Part_27), P1455-P1455. RIS download Bibtex download
  • Hicks D, Rafiee G, Schwalbe EC, Lindsey JC, Hill RM, Smith A, Crosier S, Joshi A, Robson K, Wharton S , Jacques T et al (2018) . Neuro-Oncology, 20(suppl_2), i123-i123. RIS download Bibtex download
  • Hicks D, Rafiee G, Schwalbe EC, Lindsey JC, Hill RM, Smith A, Crosier S, Joshi A, Robson K, Wharton S , Jacques T et al (2018) MBCL-30. SUBGROUP-DIRECTED CLINICAL AND MOLECULAR STRATIFICATION OF DISEASE RISK IN INFANT MEDULLOBLASTOMA.. Neuro-oncology, 20(Suppl 2), i123-i123. RIS download Bibtex download
  • Goodall EF, Wang C, Simpson JE, Baker DJ, Drew DR, Heath PR, Saffrey MJ, Romero IA & Wharton SB (2018) . Neuropathology and Applied Neurobiology, 44(3), 328-340. RIS download Bibtex download
  • Eagle D, Merla A, Ushewokunze SO, Jellinek D, Zaki H, Wharton S & Mckevitt F (2018) Genomic Analysis, Surgical Treatment and Outcomes of Lower-Grade Gliomas in a Single Institution.. Neuro-oncology, 20(Suppl 1), i20-i20. RIS download Bibtex download
  • Simpson JE, Wharton SB & Heath PR (2018) , 273-284. RIS download Bibtex download
  • Ameen-Ali KE, Wharton SB, Simpson JE, Heath PR, Sharp P & Berwick J (2017) . Neuropathology and Applied Neurobiology, 43(7), 553-570. RIS download Bibtex download
  • Kingston A, Wohland P, Wittenberg R, Robinson L, Brayne C, Matthews FE, Jagger C, Green E, Gao L, Barnes R , Arthur A et al (2017) . The Lancet. RIS download Bibtex download
  • Schwalbe EC, Lindsey JC, Nakjang S, Crosier S, Smith AJ, Hicks D, Rafiee G, Hill RM, Iliasova A, Stone T , Pizer B et al (2017) . The Lancet Oncology, 18(7), 958-971. RIS download Bibtex download
  • Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I , Attems J et al (2017) . Journal of Neuropathology and Experimental Neurology, 76(7), 605-619. RIS download Bibtex download
  • Garwood CJ, Ratcliffe LE, Simpson JE, Heath PR, Ince PG & Wharton SB (2017) . Neuropathology and Applied Neurobiology, 43(4), 281-298. RIS download Bibtex download
  • Hill R, Richardson S, Lindsey J, Crosier S, Schwalbe E, Hicks D, Rafiee G, Smithh A, Joshi A, Robson K , Wharton S et al (2017) . Neuro-Oncology, 19(suppl_4), iv41-iv41. RIS download Bibtex download
  • Hicks D, Rafiee G, Schwalbe EC, Howell CI, Lindsey JC, Hill RM, Smith A, Crosier S, Joshi A, Robson K , Wharton S et al (2017) . Neuro-Oncology, 19(suppl_4), iv39-iv39. RIS download Bibtex download
  • Schwalbe E, Lindsey J, Nakjang S, Crosier S, Smith A, Hicks D, Rafiee G, Hill R, Iliasova A, Stone T , Pizer B et al (2017) . Neuro-Oncology, 19(suppl_4), iv38-iv38. RIS download Bibtex download
  • Hill R, Richardson S, Lindsey J, Crosier S, Schwalbe E, Hicks D, Rafiee G, Smithh A, Joshi A, Robson K , Wharton S et al (2017) MEDU-16. TIME, PATTERN AND OUTCOME OF MEDULLOBLASTOMA RELAPSE IS BIOLOGY AND THERAPY-DEPENDENT. Neuro-oncology, 19(Suppl 4), iv41-iv41. RIS download Bibtex download
  • Schwalbe E, Lindsey J, Nakjang S, Crosier S, Smith A, Hicks D, Rafiee G, Hill R, Iliasova A, Stone T , Pizer B et al (2017) MEDU-06. NOVEL MOLECULAR SUBGROUPS IMPROVE CLINICAL CLASSIFICATION AND OUTCOME PREDICTION FOR CHILDHOOD MEDULLOBLASTOMA. Neuro-oncology, 19(Suppl 4), iv38-iv38. RIS download Bibtex download
  • Hicks D, Rafiee G, Schwalbe EC, Howell CI, Lindsey JC, Hill RM, Smith A, Crosier S, Joshi A, Robson K , Wharton S et al (2017) MEDU-09. SUBGROUP-DIRECTED STRATIFICATION OF DISEASE RISK IN INFANT MEDULLOBLASTOMA. Neuro-oncology, 19(Suppl 4), iv39-iv39. RIS download Bibtex download
  • Bagga V, Kailaya-Vasan A, Wharton SB & Patel U (2017) . World Neurosurgery. RIS download Bibtex download
  • Larsen J, Wharton SB, Romanowski C, McKevitt FM, Bridgewater C, Zaki H & Hoggard N (2016) . British Journal of Radiology. RIS download Bibtex download
  • Simpson JE, Waller R, Woodroofe MN, Wharton SB, Ince PG, Francese S, Heath PR, Cudzich-Madry A, Thomas R, Rounding N & Sharrack B (2016) . Journal of Neuroimmunology, 299, 139-146. RIS download Bibtex download
  • Ince PG, Minett T, Forster G, Brayne C, Wharton SB & Medical Research Council Cognitive Function Ageing Neuropathology Study (2016) . Neuropathol Appl Neurobiol. RIS download Bibtex download
  • McAleese KE, Alafuzoff I, Charidimou A, De Reuck J, Grinberg LT, Hainsworth AH, Hortobagyi T, Ince P, Jellinger K, Gao J , Kalaria RN et al (2016) . BMC Medicine, 14(1). RIS download Bibtex download
  • Appleby-Mallinder C, Wyles MD, Simpson JE, Wharton SB, Ince PG & Heath PR (2016) . Journal of Neuroscience Methods, 268, 125-130. RIS download Bibtex download
  • Hicks D, Rafiee G, Schwalbe E, Howell C, Lindsey J, Hill R, Smith A, Crosier S, Joshi A, Robson K , Wharton S et al (2016) . Neuro-Oncology, 18(suppl 3), iii111.2-iii111. RIS download Bibtex download
  • Crosier S, Hicks D, Schwalbe E, Williamson D, Nicholson S, Michalski A, Pizer B, Bailey S, Bown N, Robson K , Wharton S et al (2016) . Neuro-Oncology, 18(suppl 3), iii115.1-iii115. RIS download Bibtex download
  • Hicks D, Rafiee G, Schwalbe E, Howell C, Lindsey J, Hill R, Smith A, Crosier S, Joshi A, Robson K , Wharton S et al (2016) MB-63SUBGROUP-DIRECTED STRATIFICATION OF RISK IN INFANT MEDULLOBLASTOMA. Neuro-oncology, 18(Suppl 3), iii111-iii111. RIS download Bibtex download
  • Crosier S, Hicks D, Schwalbe E, Williamson D, Nicholson S, Michalski A, Pizer B, Bailey S, Bown N, Robson K , Wharton S et al (2016) MB-79CENTRALISED MOLECULAR PATHOLOGY FOR RARE TUMOURS: A NATIONAL FEASIBILITY STUDY OF REAL-TIME MEDULLOBLASTOMA DIAGNOSTICS. Neuro-oncology, 18(Suppl 3), iii115-iii115. RIS download Bibtex download
  • Highley JR, Pons AL, Cooper鈥怟nock J, Wharton SB, Ince PG, Shaw PJ, Wood J & Kirby J (2016) . Neuropathology and Applied Neurobiology, 42(4), 377-389. RIS download Bibtex download
  • Matthews FE, Stephan BCM, Robinson L, Jagger C, Barnes LE, Arthur A, Brayne C, Comas-Herrera A, Wittenberg R, Dening T , McCracken CFM et al (2016) . Nature Communications, 7, 11398-11398. RIS download Bibtex download
  • Lewis R, Jenkins T, Wharton S, Lorenz E, Rao G, Stevens R, Hadjivassiliou M & Blackburn D (2016) . Practical Neurology, 16(2), 153-156. RIS download Bibtex download
  • Wharton SB, Minett T, Drew D, Forster G, Matthews F, Brayne C, Ince PG & on behalf of the MRC Cognitive Function and Ageing Neuropathology Study Group (2016) . Acta Neuropathologica Communications, 4(1). RIS download Bibtex download
  • Simpson JE, Ince PG, Minett T, Matthews FE, Heath PR, Shaw PJ, Goodall E, Garwood CJ, Ratcliffe LE, Brayne C , Rattray M et al (2016) . Neuropathology and Applied Neurobiology, 42(2), 167-179. RIS download Bibtex download
  • Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B , Halliday GM et al (2016) . Acta Neuropathologica, 131(1), 87-102. RIS download Bibtex download
  • Bargiela D, Shanmugarajah P, Lo C, Blakely EL, Taylor RW, Horvath R, Wharton S, Chinnery PF & Hadjivassiliou M (2015) . Cerebellum & Ataxias, 2. RIS download Bibtex download
  • Garwood CJ, Ratcliffe LE, Morgan SV, Simpson JE, Owens H, Vazquez-Villase帽or I, Heath PR, Romero IA, Ince PG & Wharton SB (2015) . Molecular Brain, 8(1). RIS download Bibtex download
  • Fluteau A, Ince PG, Minett T, Matthews FE, Brayne C, Garwood CJ, Ratcliffe LE, Morgan S, Heath PR, Shaw PJ , Wharton SB et al (2015) . Neuroscience Letters, 609, 11-17. RIS download Bibtex download
  • Al-Mashhadi S, Simpson JE, Heath PR, Dickman M, Forster G, Matthews FE, Brayne C, Ince PG & Wharton SB (2015) . Brain Pathology, 25(5), 565-574. RIS download Bibtex download
  • Stratmann K, Heinsen H, Korf H-W, Del Turco D, Ghebremedhin E, Seidel K, Bouzrou M, Grinberg LT, Bohl J, Wharton SB , den Dunnen W et al (2015) . Brain Pathology, 26(3), 371-386. RIS download Bibtex download
  • Alafuzoff I, Pikkarainen M, Neumann M, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Bugiani O, Ferrer I, Gelpi E , Gentleman S et al (2015) . Journal of Neural Transmission, 122(7), 973-974. RIS download Bibtex download
  • Cooper-Knock J, Higginbottom A, Stopford MJ, Highley JR, Ince PG, Wharton SB, Pickering-Brown S, Kirby J, Hautbergue GM & Shaw PJ (2015) . Acta Neuropathologica, 130(1), 63-75. RIS download Bibtex download
  • Alafuzoff I, Pikkarainen M, Neumann M, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Bugiani O, Ferrer I, Gelpi E , Gentleman S et al (2015) . Journal of Neural Transmission, 122(7), 957-972. RIS download Bibtex download
  • Simpson JE, Ince PG, Matthews FE, Shaw PJ, Heath PR, Brayne C, Garwood C, Higginbottom A & Wharton SB (2015) . Neuropathology and Applied Neurobiology, 41(4), 483-496. RIS download Bibtex download
  • Gopal-Kothandapani JS, Bagga V, Wharton SB, Connolly DJ, Sinha S & Dimitri PJ (2015) . Endocrinology, Diabetes & Metabolism Case Reports, 2015. RIS download Bibtex download
  • Wharton SB, Simpson JE, Brayne C & Ince PG (2015) . Brain Pathology, 25(1), 35-43. RIS download Bibtex download
  • Hill RM, Kuijper S, Lindsey JC, Petrie K, Schwalbe EC, Barker K, Boult JKR, Williamson D, Ahmad Z, Hallsworth A , Ryan SL et al (2015) . Cancer Cell, 27(1), 72-84. RIS download Bibtex download
  • Beer AM, Cooper-Knock J, Higginbottom A, Highley JR, Wharton SB, Ince PG, Milano A, Jones AA, Al-Chalabi A, Kirby J & Shaw PJ (2015) . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16(3-4), 249-251. RIS download Bibtex download
  • Highley JR, Kirby J, Jansweijer JA, Webb PS, Hewamadduma CA, Heath PR, Higginbottom A, Raman R, Ferraiuolo L, Cooper-Knock J , McDermott CJ et al (2014) . Neuropathol Appl Neurobiol, 40(6), 670-685. RIS download Bibtex download
  • Cooper-Knock J, Walsh MJ, Higginbottom A, Robin Highley J, Dickman MJ, Edbauer D, Ince PG, Wharton SB, Wilson SA, Kirby J , Hautbergue GM et al (2014) . Brain, 137(Pt 7), 2040-2051. RIS download Bibtex download
  • Asi YT, Lees AJ, Revesz T, Holton JL, Simpson JE, Heath PR, Wharton SB & Houlden H (2014) . GLIA. RIS download Bibtex download
  • Garwood CJ, Simpson JE, Al Mashhadi S, Axe C, Wilson S, Heath PR, Shaw PJ, Matthews FE, Brayne C, Ince PG , Wharton SB et al (2014) . Neuropathol Appl Neurobiol, 40(7), 802-814. RIS download Bibtex download
  • Cooper-Knock J, Walsh M, Higginbottom A, Highley JR, Bury J, Dickman M, Rattray M, Heath P, Wyles M, Ince P , Wharton S et al (2014) . Neurology, 82(10_supplement). RIS download Bibtex download
  • Cooper-Knock J, Walsh M, Higginbottom A, Highley JR, Bury J, Dickman M, Rattray M, Heath P, Wyles M, Ince P , Wharton S et al (2014) . Neurology, 82(10_supplement). RIS download Bibtex download
  • Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B , Rohrer JD et al (2014) . Acta Neuropathol, 127(3), 407-418. RIS download Bibtex download
  • Janaway BM, Simpson JE, Hoggard N, Highley JR, Forster G, Drew D, Gebril OH, Matthews FE, Brayne C, Wharton SB , Ince PG et al (2014) . Neuropathol Appl Neurobiol, 40(3), 258-269. RIS download Bibtex download
  • Hickman SJ, Allen JA, Baisre A, Batty R, Lari HB, Melen O, Pepper IM, Sarrigiannis PG, Turbin RE, Wharton SB & McDermott CJ (2013) . Neuro-Ophthalmology, 37(4), 146-156. RIS download Bibtex download
  • Richardson K, Allen SP, Mortiboys HJ, Grierson AJ, Wharton SB, Ince PG, Shaw PJ & Heath PR (2013) . Plos One, 6(8), e68256-e68256. RIS download Bibtex download
  • Garwood C, Faizullabhoy A, Wharton SB, Ince PG, Heath PR, Shaw PJ, Baxter L, Gelsthorpe C, Forster G, Matthews FE , Brayne C et al (2013) . Neuropathol Appl Neurobiol, 39(7), 788-799. RIS download Bibtex download
  • Brayne C, Barker RA, Harold D, Ince PG, Savva GM, Williams J, Williams-Gray CH & Wharton SB (2013) . Journal of Alzheimer's Disease, 33(SUPPL. 1). RIS download Bibtex download
  • Brockington A, Ning K, Heath PR, Wood E, Kirby J, Fusi N, Lawrence N, Wharton SB, Ince PG & Shaw PJ (2013) . Acta Neuropathol, 125(1), 95-109. RIS download Bibtex download
  • Alafuzoff I, Gelpi E, Al-Sarraj S, Arzberger T, Attems J, Bodi I, Bogdanovic N, Budka H, Bugiani O, Englund E , Ferrer I et al (2012) . Experimental Gerontology, 47(11), 825-833. RIS download Bibtex download
  • Stephan BCM, Wharton SB, Simpson J, Matthews FE, Ince P & Brayne C (2012) . Neurodegenerative Disease Management, 2(5), 471-482. RIS download Bibtex download
  • Lace G, Ince PG, Brayne C, Savva GM, Matthews FE, de Silva R, Simpson JE & Wharton SB (2012) . Dement Geriatr Cogn Disord, 34(1), 15-24. RIS download Bibtex download
  • Waller R, Woodroofe MN, Francese S, Heath PR, Wharton SB, Ince PG, Sharrack B & Simpson JE (2012) . J Neurosci Methods, 208(2), 108-113. RIS download Bibtex download
  • Cooper-Knock J, Hewitt C, Highley JR, Brockington A, Milano A, Man S, Martindale J, Hartley J, Walsh T, Gelsthorpe C , Baxter L et al (2012) . Brain, 135(Pt 3), 751-764. RIS download Bibtex download
  • Brayne C, Barker RA, Harold D, Ince PG, Savva GM, Williams J, Williams-Gray CH & Wharton SB (2012) . Advances in Alzheimer's Disease, 3, 385-396. RIS download Bibtex download
  • Keage HAD, Ince PG, Matthews FE, Wharton SB, McKeith IG, Brayne C & CC75C MRCC (2012) . JOURNAL OF ALZHEIMERS DISEASE, 28(2), 485-493. RIS download Bibtex download
  • Ince PG, Highley JR, Kirby J, Wharton SB, Takahashi H, Strong MJ & Shaw PJ (2011) . Acta Neuropathol, 122(6), 657-671. RIS download Bibtex download
  • Simpson JE, Ince PG, Shaw PJ, Heath PR, Raman R, Garwood CJ, Gelsthorpe C, Baxter L, Forster G, Matthews FE , Brayne C et al (2011) . NEUROBIOL AGING, 32(10), 1795-1807. RIS download Bibtex download
  • Viggars AP, Wharton SB, Simpson JE, Matthews FE, Brayne C, Savva GM, Garwood C, Drew D, Shaw PJ & Ince PG (2011) . Neurosci Lett, 505(1), 25-30. RIS download Bibtex download
  • Simpson J, Ince P, Heath P, Raman R, Garwood C, Shaw P, Gelstorpe C, Baxter L, Forster G, Fiona M , Savva G et al (2011) . Alzheimer's & Dementia, 7, S566-S566. RIS download Bibtex download
  • Keage H, Ince P, Matthews F, Wharton S, McKieth I & Brayne C (2011) . Alzheimer's & Dementia, 7, S606-S607. RIS download Bibtex download
  • Langheinrich TC, Romanowski CAJ, Wharton S & Hadjivassiliou M (2011) . NEUROLOGY, 76(16), 1435-1436. RIS download Bibtex download
  • Wharton SB, Brayne C, Savva GM, Matthews FE, Forster G, Simpson J, Lace G, Ince PG & Medical Research Council Cognitive Function and Aging Study (2011) . J Alzheimers Dis, 25(2), 359-372. RIS download Bibtex download
  • Kirby J, Ning K, Ferraiuolo L, Heath PR, Ismail A, Kuo S-W, Valori CF, Cox L, Sharrack B, Wharton SB , Ince PG et al (2011) . Brain, 134(Pt 2), 506-517. RIS download Bibtex download
  • Viggars AP, Wharton SB, Simpson JE, Matthews FE, Brayne C, Savva GM, Garwood C, Drew D, Shaw PJ & Ince PG (2011) . Neuroscience Letters, 505(1), 25-30. RIS download Bibtex download
  • Simpson JE, Wharton SB, Cooper J, Gelsthorpe C, Baxter L, Forster G, Shaw PJ, Savva G, Matthews FE, Brayne C & Ince PG (2010) . Neurosci Lett, 486(3), 246-251. RIS download Bibtex download
  • Hadjivassiliou M, Rao DG, Wharton SB, Sanders DS, Gr眉newald RA & Davies-Jones AGB (2010) . Neurology, 75(11), 1003-1008. RIS download Bibtex download
  • Rajaram S, Wharton SB, Shackley F, Raghavan A & Connolly DJA (2010) . Pediatr Radiol, 40 Suppl 1, S145-S149. RIS download Bibtex download
  • Kirby J, Goodall EF, Smith W, Highley JR, Masanzu R, Hartley JA, Hibberd R, Hollinger HC, Wharton SB, Morrison KE , Ince PG et al (2010) . Neurogenetics, 11(2), 217-225. RIS download Bibtex download
  • Simpson JE, Ince PG, Lace G, Forster G, Shaw PJ, Matthews F, Savva G, Brayne C, Wharton SB & MRC Cognitive Function and Ageing Neuropathology Study Group (2010) . Neurobiol Aging, 31(4), 578-590. RIS download Bibtex download
  • Simpson JE, Ince PG, Haynes LJ, Theaker R, Gelsthorpe C, Baxter L, Forster G, Lace GL, Shaw PJ, Matthews FE , Savva GM et al (2010) . Neuropathol Appl Neurobiol, 36(1), 25-40. RIS download Bibtex download
  • Simpson JE, Wharton SB, Cooper J, Gelsthorpe C, Baxter L, Forster G, Shaw PJ, Savva G, Matthews FE, Brayne C & Ince PG (2010) . Neuroscience Letters, 486(3), 246-251. RIS download Bibtex download
  • Cox LE, Ferraiuolo L, Goodall EF, Heath PR, Higginbottom A, Mortiboys H, Hollinger HC, Hartley JA, Brockington A, Burness CE , Morrison KE et al (2010) . PLoS One, 5(3), e9872. RIS download Bibtex download
  • Matthews FE, Brayne C, Lowe J, McKeith I, Wharton SB & Ince P (2009) . PLOS MED, 6(11). RIS download Bibtex download
  • Blackburn D, Highley JR, Wharton S, Romanowski C, Bowen J & Sharrack B (2009) . APMIS, 117(10), 768-772. RIS download Bibtex download
  • Savva GM, Wharton SB, Ince PG, Forster G, Matthews FE, Brayne C & Med Res Council Cognitive Function (2009) Age, Neuropathology, and Dementia. NEW ENGL J MED, 360(22), 2302-2309. RIS download Bibtex download
  • Lace G, Savva GM, Forster G, de Silva R, Brayne C, Matthews FE, Barclay JJ, Dakin L, Ince PG, Wharton SB & MRC-CFAS (2009) . Brain, 132(Pt 5), 1324-1334. RIS download Bibtex download
  • Alafuzoff I, Thal DR, Arzberger T, Bogdanovic N, Al-Sarraj S, Bodi I, Boluda S, Bugiani O, Duyckaerts C, Gelpi E , Gentleman S et al (2009) . ACTA NEUROPATHOL, 117(3), 309-320. RIS download Bibtex download
  • Simpson JE, Hosny O, Wharton SB, Heath PR, Holden H, Fernando MS, Matthews F, Forster G, O'Brien JT, Barber R , Kalaria RN et al (2009) . Stroke, 40(2), 369-375. RIS download Bibtex download
  • Keage HAD, Carare RO, Friedland RP, Ince PG, Love S, Nicoll JA, Wharton SB, Weller RO & Brayne C (2009) . BMC NEUROL, 9. RIS download Bibtex download
  • Wharton SB, O'Callaghan JP, Savva GM, Nicoll JAR, Matthews F, Simpson JE, Forster G, Shaw PJ, Brayne C, Ince PG & MRC Cognitive Function and Ageing Neuropathology Study Group (2009) . Dement Geriatr Cogn Disord, 27(5), 465-473. RIS download Bibtex download
  • Kasher PR, De Vos KJ, Wharton SB, Manser C, Bennett EJ, Bingley M, Wood JD, Milner R, McDermott CJ, Miller CCJ , Shaw PJ et al (2009) . J Neurochem, 110(1), 34-44. RIS download Bibtex download
  • Alafuzoff I, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Braak H, Bugiani O, Del-Tredici K, Ferrer I, Gelpi E , Giaccone G et al (2008) . BRAIN PATHOL, 18(4), 484-496. RIS download Bibtex download
  • Wharton S (2008) . Neuropathology and Applied Neurobiology, 34(1), 1-3. RIS download Bibtex download
  • Romanowski CAJ, Hoggard N, Jellinek DA, Levy D, Wharton SB, Kotsarini C, Batty R & Wilkinson ID (2008) . Neuroradiology Journal, 21(SUPPL. 1), 47-66. RIS download Bibtex download
  • Simpson JE, Ince PG, Higham CE, Gelsthorpe CH, Fernando MS, Matthews F, Forster G, O'Brien JT, Barber R, Kalaria RN , Brayne C et al (2007) . Neuropathol Appl Neurobiol, 33(6), 670-683. RIS download Bibtex download
  • Simpson JE, Fernando MS, Clark L, Ince PG, Matthews F, Forster G, O'Brien JT, Barber R, Kalaria RN, Brayne C , Shaw PJ et al (2007) . Neuropathol Appl Neurobiol, 33(4), 410-419. RIS download Bibtex download
  • Hadjivassiliou M, Chattopadhyay AK, Gr眉newald RA, Jarratt JA, Kandler RH, Rao DG, Sanders DS, Wharton SB & Davies-Jones GAB (2007) . Muscle Nerve, 35(4), 443-450. RIS download Bibtex download
  • Lace GL, Wharton SB & Ince PG (2007) . Clin Neuropathol, 26(2), 43-58. RIS download Bibtex download
  • Wharton SB, Maltby E, Jellinek DA, Levy D, Atkey N, Hibberd S, Crimmins D, Stoeber K & Williams GH (2007) . Acta Neuropathol, 113(2), 119-127. RIS download Bibtex download
  • Taha M, Patel U, Wharton SB, Cooper PC & Makris M (2007) . J Neurosurg, 106(2 Suppl), 143-146. RIS download Bibtex download
  • Wharton S (2007) . Neuropathology and Applied Neurobiology, 33(1), 1-1. RIS download Bibtex download
  • Hadjivassiliou M, Gr眉newald RA, Kandler RH, Chattopadhyay AK, Jarratt JA, Sanders DS, Sharrack B, Wharton SB & Davies-Jones GAB (2006) . J Neurol Neurosurg Psychiatry, 77(11), 1262-1266. RIS download Bibtex download
  • Fernando MS, Simpson JE, Matthews F, Brayne C, Lewis CE, Barber R, Kalaria RN, Forster G, Esteves F, Wharton SB , Shaw PJ et al (2006) . Stroke, 37(6), 1391-1398. RIS download Bibtex download
  • Brockington A, Wharton SB, Fernando M, Gelsthorpe CH, Baxter L, Ince PG, Lewis CE & Shaw PJ (2006) . J Neuropathol Exp Neurol, 65(1), 26-36. RIS download Bibtex download
  • Baron P, Bussini S, Cardin V, Corbo M, Conti G, Galimberti D, Scarpini E, Bresolin N, Wharton SB, Shaw PJ & Silani V (2005) . MUSCLE NERVE, 32(4), 541-544. RIS download Bibtex download
  • Taha M, Ahmad A, Wharton S & Jellinek D (2005) . Br J Neurosurg, 19(4), 348-351. RIS download Bibtex download
  • Wharton SB, Williams GH, Stoeber K, Gelsthorpe CH, Baxter L, Johnson AL, Ince PG & MRC-CFAS (2005) . Neurosci Lett, 383(1-2), 33-38. RIS download Bibtex download
  • Bell HS, Whittle IR, Bader SA & Wharton SB (2005) . NEUROPATH APPL NEURO, 31(2), 191-202. RIS download Bibtex download
  • Newbery HJ, Gillingwater TH, Dharmasaroja P, Peters J, Wharton SB, Thomson D, Ribchester RR & Abbott CM (2005) Progressive loss of motor neuron function in wasted mice: Effects of a spontaneous null mutation in the gene for the eEF1A2 translation factor. J NEUROPATH EXP NEUR, 64(4), 295-303. RIS download Bibtex download
  • Henson JD, Hannay JA, McCarthy SW, Royds JA, Yeager TR, Robinson RA, Wharton SB, Jellinek DA, Arbuckle SM, Yoo JY , Robinson BG et al (2005) A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas. CLIN CANCER RES, 11(1), 217-225. RIS download Bibtex download
  • Ince PG & Wharton SB (2004) , 149-167. RIS download Bibtex download
  • Brockington A, Lewis C, Wharton S & Shaw PJ (2004) . Neuropathol Appl Neurobiol, 30(5), 427-446. RIS download Bibtex download
  • Wharton SB, Hibberd S, Eward KL, Crimmins D, Jellinek DA, Levy D, Stoeber K & Williams GH (2004) . Br J Cancer, 91(2), 262-269. RIS download Bibtex download
  • Goel S, Wharton SB, Brett LP & Whittle IR (2003) Morphological changes and stress responses in neurons in cerebral cortex infiltrated by diffuse astrocytoma. NEUROPATHOLOGY, 23(4), 262-270. RIS download Bibtex download
  • McDermott CJ, Grierson AJ, Wood JD, Bingley M, Wharton SB, Bushby KMD & Shaw PJ (2003) . Ann Neurol, 54(6), 748-759. RIS download Bibtex download
  • Wharton SB, McDermott CJ, Grierson AJ, Wood JD, Gelsthorpe C, Ince PG & Shaw PJ (2003) . J Neuropathol Exp Neurol, 62(11), 1166-1177. RIS download Bibtex download
  • Wharton SB, Wardle C, Ironside JW, Wallace WH, Royds JA & Hammond DW (2003) . Neuropathol Appl Neurobiol, 29(3), 254-261. RIS download Bibtex download
  • Ince PG, Evans J, Knopp M, Forster G, Hamdalla HHM, Wharton SB & Shaw PJ (2003) . Neurology, 60(8), 1252-1258. RIS download Bibtex download
  • Allen S, Heath PR, Kirby J, Wharton SB, Cookson MR, Menzies FM, Banks RE & Shaw PJ (2003) . J Biol Chem, 278(8), 6371-6383. RIS download Bibtex download
  • Wharton SB (2003) . The Journal of Pathology, 199(2), 271-271. RIS download Bibtex download
  • Miller MW, Peter A, Wharton SB & Wyllie AH (2003) . Brain Research, 965(1-2), 57-66. RIS download Bibtex download
  • Yamaguchi S, Bell HS, Shinoda J, Holmes MC, Wharton SB & Whittle IR (2002) Glioma tumourgenicity is decreased by iNOS knockout: experimental studies using the C6 striatal implantation glioma model. BRIT J NEUROSURG, 16(6), 567-572. RIS download Bibtex download
  • Leaver HA, Wharton SB, Bell HS, Leaver-Yap IMM & Whittle IR (2002) . PROSTAG LEUKOTR ESS, 67(5), 283-292. RIS download Bibtex download
  • Horsburgh MJ, Wharton SJ, Karavolos M & Foster SJ (2002) . Trends in Microbiology, 10(11), 496-501. RIS download Bibtex download
  • Ramaesh K, Bhagat S, Wharton SB & Singh J (2002) . EYE, 16(5), 670-673. RIS download Bibtex download
  • Whittle IR, Mitchener A, Atkinson HD & Wharton SB (2002) . ACTA NEUROPATHOL, 104(2), 215-215. RIS download Bibtex download
  • Wharton SB, Whittle IR, Collie DA, Bell HS & Ironside JW (2002) Gliosarcoma with areas of primitive neuroepithelial differentiation and extracranial metastasis - Reply. CLIN NEUROPATHOL, 21(4), 195-196. RIS download Bibtex download
  • Wharton SB, Chan KK & Whittle IR (2002) . J CLIN NEUROSCI, 9(2), 165-169. RIS download Bibtex download
  • Taguri AH, Dhillon B, Wharton SB & Kamal A (2002) . Am J Ophthalmol, 133(1), 147-149. RIS download Bibtex download
  • Leaver HA, Bell HS, Rizzo MT, Ironside JW, Gregor A, Wharton SB & Whittle IR (2002) . Prostaglandins Leukot Essent Fatty Acids, 66(1), 19-29. RIS download Bibtex download
  • Kepes JJ, Wharton SB, Whittle IR, Collie DA, Bell HS & Ironside JW (2002) Gliosarcoma with areas of primitive neuroepithelial differentiation and extracranial metastasis [2] (multiple letters). Clinical Neuropathology, 21(4), 193-196. RIS download Bibtex download
  • Lo S, Bell HS, Yamaguchi S, Wharton SB & Whittle IR (2001) . Br J Neurosurg, 15(5), 416-418. RIS download Bibtex download
  • Wharton SB, Whittle IR, Collie DA, Bell HS & Ironside JW (2001) Gliosarcoma with areas of primitive neuroepithelial differentiation and extracranial metastasis.. Clin Neuropathol, 20(5), 212-218. RIS download Bibtex download
  • Bell HS, Whittle IR, Walker M, Leaver HA & Wharton SB (2001) . Neuropathol Appl Neurobiol, 27(4), 291-304. RIS download Bibtex download
  • Wharton SB, Chan KK, Anderson JR, Stoeber K & Williams GH (2001) . Neuropathol Appl Neurobiol, 27(4), 305-313. RIS download Bibtex download
  • Ramaesh K, Wharton SB & Dhillon B (2001) . Eye (Lond), 15(Pt 3), 309-312. RIS download Bibtex download
  • Singh J, Ramaesh K, Wharton SB, Cormack G & Chawla HB (2001) . Retina, 21(3), 247-251. RIS download Bibtex download
  • Wharton SB, Lammie GA, Collie DA & Whittle IR (2000) . Acta Neuropathol, 100(6), 695-700. RIS download Bibtex download
  • Wharton SB, McNelis U, Bell HS & Whittle IR (2000) . Neuropathol Appl Neurobiol, 26(6), 528-535. RIS download Bibtex download
  • Brewis C, Bottrill ID, Wharton SB, Path & Moffat (2000) . The Journal of Laryngology & Otology, 114(1), 17-23. RIS download Bibtex download
  • Brewis C, Bottrill ID, Wharton SB & Moffat DA (2000) . The Journal of Laryngology & Otology, 114(1), 67-69. RIS download Bibtex download
  • Bhagat S, Ramaesh K, Wharton SB & Dhillon B (1999) Spontaneous acute scleritis and scleral necrosis in choroidal malignant melanoma. EYE, 13, 793-795. RIS download Bibtex download
  • Bell HS, Wharton SB, Leaver HA & Whittle IR (1999) . J Neurosurg, 91(6), 989-996. RIS download Bibtex download
  • Waring WS, Wharton SB, Grant R & McIntyre M (1999) . Clin Neurol Neurosurg, 101(4), 275-279. RIS download Bibtex download
  • Delgado MB, Anderson JR, Whittle IR & Wharton SB (1999) . Neuropathol Appl Neurobiol, 25(5), 400-407. RIS download Bibtex download
  • Ramaesh K, Bhagat S, Wharton SB & Singh J (1999) . Arch Ophthalmol, 117(10), 1411-1413. RIS download Bibtex download
  • Ramaesh K, Marshall JW, Wharton SB & Dhillon B (1999) . Eye (Lond), 13 ( Pt 2), 247-250. RIS download Bibtex download
  • Hutchinson PJ, O'Connell MT, Al-Rawi PG, Maskell LB, Gupta AK, Hutchinson DB, Pickard JD, Kirkpatrick PJ & Wharton SB (1999) Neuropathological findings after intracerebral implantation of microdialysis catheters in sheep forebrain.. Neuroreport, 10(3). RIS download Bibtex download
  • Waite KJ, Wharton SB, Old SE & Burnet NG (1999) Systemic metastases of glioblastoma multiforme. CLIN ONCOL-UK, 11(3), 205-207. RIS download Bibtex download
  • Leaver HA, Whittle IR, Wharton SB & Ironside JW (1998) . Br J Neurosurg, 12(6), 539-546. RIS download Bibtex download
  • Robertson NP, Wharton S, Anderson J & Scolding NJ (1998) . Journal of Neurology, Neurosurgery & Psychiatry, 65(5), 788-790. RIS download Bibtex download
  • Wharton SB, Chan KK, Hamilton FA & Anderson JR (1998) . Neuropathol Appl Neurobiol, 24(4), 302-308. RIS download Bibtex download
  • Wharton SB, Hamilton FA, Chan WK, Chan KK & Anderson JR (1998) Proliferation and cell death in oligodendrogliomas. NEUROPATH APPL NEURO, 24(1), 21-28. RIS download Bibtex download
  • Wharton SB, Antoun NM, Macfarlane R & Anderson JR (1998) The natural history of a recurrent central neurocytoma-like tumor.. Clin Neuropathol, 17(3), 136-140. RIS download Bibtex download
  • Lau DPC, Wharton SB, Antoun NM, Bottrill ID & Moffat DA (1997) . The Journal of Laryngology & Otology, 111(4), 368-371. RIS download Bibtex download
  • Wharton SB, Chan KK, Pickard JD & Anderson JR (1996) . Journal of Neurology, Neurosurgery & Psychiatry, 61(5), 461-465. RIS download Bibtex download
  • Wharton SB, Meyers NL & Nash AA (1995) . Neuropathology and Applied Neurobiology, 21(3), 228-237. RIS download Bibtex download
  • Wharton SB & Nash AA (1993) . Current Opinion in Neurobiology, 3(5), 768-772. RIS download Bibtex download
  • Almansouri T, Waller R, Wharton SB, Heath PR, Matthews FE, Brayne C, van Eeden F & Simpson JE () . International Journal of Molecular Sciences, 25(8), 4445-4445. RIS download Bibtex download
  • Wharton SB, Simpson JE, Ince PG, Richardson CD, Merrick R, Matthews FE & Brayne C () . Neuropathology and Applied Neurobiology. RIS download Bibtex download
  • Cooper鈥怟nock J, Julian TH, Feneberg E, Highley JR, Sidra M, Turner MR, Talbot K, Ansorge O, Allen SP, Moll T , Shelkovnikova T et al () . Brain Pathology. RIS download Bibtex download
  • V谩zquez-Villase帽or I, Smith CI, Thang YJR, Heath PR, Wharton SB, Blackburn DJ, Ridger VC & Simpson JE () . International Journal of Molecular Sciences, 23(11), 5913-5913. RIS download Bibtex download
  • Richardson S, Hill RM, Kui C, Lindsey JC, Grabovksa Y, Keeling C, Pease L, Bashton M, Crosier S, Vinci M , Andr茅 N et al () . Neuro-Oncology. RIS download Bibtex download
  • Shabir O, Pendry B, Lee L, Eyre B, Sharp P, Rebollar MA, Howarth C, Heath PR, Wharton SB, Francis SE & Berwick J () . RIS download Bibtex download
  • Shabir O, Pendry B, Heath PR, Rebollar MA, Howarth C, Wharton SB, Berwick J & Francis SE () . RIS download Bibtex download
  • Ameen-Ali KE, Simpson JE, Wharton SB, Heath PR, Sharp P, Brezzo G & Berwick J () . RIS download Bibtex download
  • Sharp PS, Ameen-Ali K, Boorman L, Harris S, Wharton S, Howarth C, Redgrave P & Berwick J () . RIS download Bibtex download
  • Gopal-Kothandapani JS, Bagga V, Wharton SB, Connolly DJ, Sinha S & Dimitri P () . Endocrine Abstracts. RIS download Bibtex download
  • Mathur R, Ince PG, Minett T, Garwood CJ, Shaw PJ, Matthews FE, Brayne C, Simpson JE & Wharton SB () . PLoS ONE, 10(2). RIS download Bibtex download
  • Shabir O, Pendry B, Lee L, Eyre B, Sharp P, Rebollar M, Drew D, Howarth C, Heath P, Wharton S , Francis S et al () . eLife. RIS download Bibtex download

Chapters

  • Highley JR & Wharton SB (2024) , Greenfield's Neuropathology 10e Set (pp. 875-906). CRC Press RIS download Bibtex download
  • Ince PG, Highley JR & Wharton SB (2015) Motor neuron disorders In Love S, Budka H, Ironside JW & Perry A (Ed.), Greenfield's Neuropathology (pp. 817-848). Boca Raton: CRC Press. RIS download Bibtex download
  • Ince PG & Wharton SB (2007) (pp. 89-119). RIS download Bibtex download
  • Wharton S & Ince PG (2003) , Motor Neuron Disorders (pp. 17-49). Elsevier RIS download Bibtex download

Conference proceedings papers

  • Thang Y, Vazquez-Villasenor I, Smith C, Blackburn D, Wharton S, Heath P, Ridger V & Simpson J (2022) The miRNA profile of neutrophil-derived microvesicles may impact blood-brain barrier integrity in Alzheimer's disease. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 48 RIS download Bibtex download
  • Matuszyk M, Ferraiuolo L, Taylor A, Davis P, Staniforth R, Garwood C, Simpson J & Wharton S (2022) Characterising the astrocyte response to oligomeric and fibrillary A beta 1-42 in Alzheimer's disease. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 48 RIS download Bibtex download
  • Floare M, Simpson J, Wharton S, Aeschlimann D & Hadjivassiliou M (2022) Demystifying the gluten brain: Understanding the origin of gluten-related neurological disorders. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 48 RIS download Bibtex download
  • Almansouri T, Heath P, Wharton S, Van Eeden F & Simpson J (2022) Microarray approach to identifying the role of microglia in the pathogenesis of age-associated deep-subcortical white matter lesions. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 48 RIS download Bibtex download
  • Waller R, Heath PR, Simpson JE, Hase Y, Kalaria RN & Wharton SB (2021) What happens to cells of the brain in people who develop dementia after stroke?. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 47 (pp 8-8) RIS download Bibtex download
  • Guagnelli MAR, Wharton S, Francis S & Simpson J (2021) The effect of systemic atherosclerosis on the neurovascular unit. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 47 (pp 21-21) RIS download Bibtex download
  • Bury J, Chambers A, Heath P, Ince P, Shaw P, Matthew F, Brayne C & Wharton S (2021) Effects of Type 2 Diabetes on Neuronal and Associated Neurovascular Unit Transcriptomes. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 47 (pp 8-8) RIS download Bibtex download
  • Matuszyk M, Ferraiuolo L, Taylor A, Davies P, Staniforth R, Garwood C & Wharton S (2021) Characterising the varying astrocyte response to oligomeric and fibrillar A beta(1-42). NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 47 (pp 18-19) RIS download Bibtex download
  • Jennings O, Ajikumar A, Heath PR, Wharton SB & Simpson JE (2020) Transcriptomic profile of the blood-brain barrier in age-associated white matter lesions. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 46 (pp 46-46) RIS download Bibtex download
  • Hase Y, Foster V, Waller R, Simpson JE, Heath P, Wharton SB & Kalaria RN (2020) 121st Meeting of the British Neuropathological Society UCL Great Ormond Street Institute of Child Health, London. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 46 (pp 14-15) RIS download Bibtex download
  • Matuszyk MM, Ferraiuolo L, Taylor A, Davis P, Staniforth R, Garwood CJ & Wharton SB (2020) Characterising the varying astrocyte response to oligomeric and fibrillar A beta. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 46 (pp 25-25) RIS download Bibtex download
  • Das J, Gill A, Lo C, Chan-Lam N, Price S, Wharton S, Jessop H, Sharrack B & Snowden J (2020) Multiple sclerosis-like CNS inflammation following allogeneic haematopoietic stem cell transplantation treated with a 'domino' autologous haematopoietic stem cell transplantation. NEUROLOGY, Vol. 94(15) RIS download Bibtex download
  • Hill R, Richardson S, Schwalbe E, Hicks D, Lindsey J, Crosier S, Rafiee G, Grabovska Y, Wharton S, Jacques T , Michalski A et al (2020) TIME, PATTERN AND OUTCOME OF MEDULLOBLASTOMA RELAPSE ARE ASSOCIATED WITH TUMOUR BIOLOGY AT DIAGNOSIS AND UPFRONT THERAPY: A COHORT STUDY. NEURO-ONCOLOGY, Vol. 22 (pp 405-406) RIS download Bibtex download
  • Richardson S, Hill RM, Kui C, Lindsey JC, Grabovska Y, Schwalbe EC, Hicks D, Williamson D, Crosier S, Joshi A , Wharton SB et al (2020) THE ACTIONABLE GENOMIC LANDSCAPE OF RELAPSED MEDULLOBLASTOMA IS DEFINED BY MAINTENANCE AND ACQUISITION OF DRIVER EVENTS. NEURO-ONCOLOGY, Vol. 22 (pp 408-408) RIS download Bibtex download
  • Hicks D, Rafiee G, Schwalbe E, Howell C, Lindsey J, Hill R, Smith A, Adidharma P, Steel C, Pease L , Crosier S et al (2019) The Molecular Landscape and Clinical Experience in Infant Medulloblastoma. PEDIATRIC BLOOD & CANCER, Vol. 66 (pp S4-S4) RIS download Bibtex download
  • Fadul MM, Heath P, Cooper-Knock J, Brayne C, Matthews F, Wharton S & Simpson J (2019) A microarray analysis approach to identify mechanisms underlying the pathogenesis of age-associated periventricular white matter lesions. GLIA, Vol. 67 (pp E300-E300) RIS download Bibtex download
  • Hicks D, Rafiee G, Schwalbe EC, Lindsey JC, Hill RM, Smith A, Crosier S, Joshi A, Robson K, Wharton S , Jacques T et al (2018) SUBGROUP-DIRECTED CLINICAL AND MOLECULAR STRATIFICATION OF DISEASE RISK IN INFANT MEDULLOBLASTOMA. NEURO-ONCOLOGY, Vol. 20 (pp 123-123) RIS download Bibtex download
  • Seehra RS, Wharton S, Heath P, Ince P, Muthana M, Garwood C & Simpson J (2018) Hypoxia-induced changes in astrocytes and their role in the formation of age-associated white matter lesions. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 44 (pp 17-18) RIS download Bibtex download
  • Chambers A, Minett T, Matthews F, Brayne C, Ince P, Shaw P, Heath P, Simpson J & Wharton S (2018) Advanced glycosylated end products in the ageing brain. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 44 (pp 12-12) RIS download Bibtex download
  • Leach V, Goodall E, Cooper-Knock J, Wang J, Simpson J, Baker D, Drew D, Saffrey J, Romero I, Heath P & Wharton S (2018) Identification of miRNA and mRNA regulatory networks in the ageing blood-brain barrier: Comparative gene expression studies in human and mouse. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 44 (pp 36-36) RIS download Bibtex download
  • Eagle D, Merla A, Ushewokunze SO, Jellinek D, Zaki H, Wharton S & Mckevitt F (2018) . Neuro-Oncology, Vol. 20(suppl_1) (pp i20-i20) RIS download Bibtex download
  • Eagle D, Merla A, McKevitt F, Clenton S, Bridgewater C, Wharton S, Zaki H, Jellinek D & Ushewokunze S (2017) GENOMIC ANALYSIS, SURGICAL TREATMENT AND OUTCOMES OF LOWER-GRADE GLIOMAS IN A SINGLE INSTITUTION. NEURO-ONCOLOGY, Vol. 19 (pp 238-238) RIS download Bibtex download
  • Hill R, Richardson S, Lindsey J, Crosier S, Schwalbe E, Hicks D, Rafiee G, Smith A, Joshi A, Robson K , Wharton S et al (2017) Time, Pattern and Outcome of Medulloblastoma Relapse is Biology and Therapy-Dependent. PEDIATRIC BLOOD & CANCER, Vol. 64 (pp S13-S14) RIS download Bibtex download
  • Hicks D, Rafiee G, Schwalbe EC, Howell CI, Lindsey JC, Hill RM, Smith A, Crosier S, Joshi A, Robson K , Wharton S et al (2017) SUBGROUP-DIRECTED STRATIFICATION OF DISEASE RISK IN INFANT MEDULLOBLASTOMA. NEURO-ONCOLOGY, Vol. 19 (pp 39-39) RIS download Bibtex download
  • Hill R, Richardson S, Lindsey J, Crosier S, Schwalbe E, Hicks D, Rafiee G, Smithh A, Joshi A, Robson K , Wharton S et al (2017) TIME, PATTERN AND OUTCOME OF MEDULLOBLASTOMA RELAPSE IS BIOLOGY AND THERAPY-DEPENDENT. NEURO-ONCOLOGY, Vol. 19 (pp 41-41) RIS download Bibtex download
  • Vazquez-Villasenor I, Simpson JE, Garwood CJ, Ince PG, Heath PR & Wharton SB (2017) Neuronal senescence as a contributor to neurodegeneration. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 43 (pp 43-43) RIS download Bibtex download
  • Ameen-Ali KE, Simpson JE, Wharton SB, Heath PR, Sharp P & Berwick J (2017) Early cellular changes and cognitive decline in an Alzheimer's mouse model. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 43 (pp 42-43) RIS download Bibtex download
  • Crosier S, Hicks D, Schwalbe E, Williamson D, Nicholson S, Michalski A, Pizer B, Bailey S, Bown N, Robson K , Wharton S et al (2016) CENTRALISED MOLECULAR PATHOLOGY FOR RARE TUMOURS: A NATIONAL FEASIBILITY STUDY OF REAL-TIME MEDULLOBLASTOMA DIAGNOSTICS. NEURO-ONCOLOGY, Vol. 18 (pp 115-115) RIS download Bibtex download
  • Hicks D, Rafiee G, Schwalbe E, Howell C, Lindsey J, Hill R, Smith A, Crosier S, Joshi A, Robson K , Wharton S et al (2016) SUBGROUP-DIRECTED STRATIFICATION OF RISK IN INFANT MEDULLOBLASTOMA. NEURO-ONCOLOGY, Vol. 18 (pp 111-111) RIS download Bibtex download
  • Ratcliffe L, Garwood CJ, Heath P, Villasenor I, Simpson J, Ince PG & Wharton SB (2016) Impairment of IGF1 signalling in human astrocytes and it's effect on astrocyte support for neurons. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 42 (pp 51-52) RIS download Bibtex download
  • Vazquez-Villasenor I, Simpson JE, Garwood C, Ince PG, Heath P & Wharton SB (2016) Neuronal senescence as a contributor to neurodegeneration. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 42 (pp 27-28) RIS download Bibtex download
  • Clifford SC, Crosier S, Hicks D, Nicholson S, Robson K, Jacques TS, Wharton S, Bown N, Michalski A & Pizer B (2016) Establishment of national real-time central pathology review (CPR) and molecular diagnostics for medulloblastoma (MB). NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 42 (pp 19-20) RIS download Bibtex download
  • Ince PG, Minett T, Forster G & Wharton SB (2015) Microinfarcts, Small Vessel Disease and Dementia in the population-representative CFAS brain donor cohort. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 41 (pp 22-23) RIS download Bibtex download
  • Vazquez-Villasenor I, Simpson JE, Garwood C, Ince PG, Heath P & Wharton SB (2015) Neuronal senescence as a contributor to neurodegeneration. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 41 (pp 32-32) RIS download Bibtex download
  • Hill RM, Kuijper S, Lindsey J, Schwalbe EC, Barker K, Boult J, Williamson D, Ahmad Z, Hallsworth A, Ryan S , Poon E et al (2014) . Tumor Biology RIS download Bibtex download
  • Beer A, Cooper-Knock J, Higginbottom A, Robin Highley J, Wharton SP, Milano A, Jones A, Al-Chalabi A, Kirby J & Shaw PJ (2014) . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 85(10) (pp e4.130-e4) RIS download Bibtex download
  • Al-Mashhadi SA, Simpson JE, Heath PR, Dickman MJ, Ince PG & Wharton SB (2014) Oxidative stress and DNA damage in cerebral white matter lesions of the ageing human brain. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 40 (pp 33-34) RIS download Bibtex download
  • Simpson JE, Ince PG, Matthews F, Shaw PJ, Heath PR, Brayne C, Garwood C, Abdalla H, Higginbottom A & Wharton SB (2014) A neuronal DNA damage response is detected at low Braak stages and correlates with cognitive impairment in the ageing brain. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 40 (pp 31-32) RIS download Bibtex download
  • Highley JR, Cooper-Knock J, Frolov A, Charlesworth G, Kirby J, Wharton SB, Ince PG, Shaw PJ, Wood N & Bandman O (2013) A pathological basis for the association of parkinsonism and amyotrophic lateral sclerosis. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 39 (pp 51-51) RIS download Bibtex download
  • Clifford S, Crosier S, Nicholson S, Robson K, Jacques T, Wharton S, Bown N, Michalski A & Pizer B (2013) A national feasibility study of real-time central pathology review (CPR) and molecular diagnostics for medulloblastoma. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 39 (pp 20-20) RIS download Bibtex download
  • Al-Mashhadi SA, Simpson JE, Heath PR, Dickman MJ, Ince PG & Wharton SB (2013) Oxidative stress and DNA damage in cerebral white matter lesions of the ageing human brain. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 39 (pp 36-37) RIS download Bibtex download
  • Ince PG, Janaway B, Wharton SB, Simpson JE, Highley JR, Matthews FE, Forster G & Brayne C (2013) Evidence for an ischemic origin of deep brain 'microbleeds'. CEREBROVASCULAR DISEASES, Vol. 35 (pp 42-42) RIS download Bibtex download
  • Waller R, Heath PR, Woodroofe MN, Francese S, Wharton SB, Ince PG, Sharrack B & Simpson JE (2012) Microarray analysis of the astrocyte transcriptome in normal appearing white matter in multiple sclerosis. JOURNAL OF NEUROIMMUNOLOGY, Vol. 253(1-2) (pp 54-54) RIS download Bibtex download
  • Crosier S, Nicholson SL, Robson K, Jacques T, Wharton S, Bown N, Michalski A, Pizer B & Clifford S (2012) A NATIONAL FEASIBILITY STUDY OF REAL-TIME CENTRAL PATHOLOGY REVIEW AND MOLECULAR DIAGNOSTICS FOR MEDULLOBLASTOMA. NEURO-ONCOLOGY, Vol. 14 (pp 44-44) RIS download Bibtex download
  • Brockington A, Ning K, Heath P, Wood E, Malik K, Fusi N, Wharton S, Ince PG & Shaw PJ (2012) . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 83(3) RIS download Bibtex download
  • Romanowski CA, Hoggard N, Jellinek DA, Clenton S, McKevitt F, Wharton S, Craven I, Buller A, Waddle C, Bigley J , Wilkinson ID et al (2011) SEMI-AUTOMATED VOLUMETRIC ANALYSIS OF LOW-GRADE GLIOMAS. NEURO-ONCOLOGY, Vol. 13 (pp 140-140) RIS download Bibtex download
  • Simpson J, Richardson K, Heath P & Wharton S (2011) Oxidative nucleic acid damage in motor neuron disease. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 37 (pp 36-36) RIS download Bibtex download
  • Nicholson SL, Robson DK, Wharton SB, Jacques TS, Michalski AM, Pizer B, Bown NP & Clifford SC (2011) A feasibility study of real-time central pathology review (CPR) and molecular diagnostics for medulloblastoma in the United Kingdom. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 37 (pp 18-19) RIS download Bibtex download
  • Simpson JE, Ince PG, Heath PR, Raman R, Shaw PJ, Gelsthorpe C, Baxter L, Forster G, Matthews F, Savva G , Brayne C et al (2011) Microarray analysis of the astrocyte transcriptome in the ageing brain: relationship to Alzheimer's pathology and ApoE genotype. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 37 (pp 33-33) RIS download Bibtex download
  • Rashbass J, Collins VP & Wharton SB (2011) The development of the National Brain and CNS Tumour Registry. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 37 (pp 19-19) RIS download Bibtex download
  • Simpson J, Ince P, Heath P, Raman R, Shaw P, Gelsthorpe C, Baxter L, Forster G, Matthews F, Savva G , Brayne C et al (2010) Microarray analysis of the astrocyte transcriptome in the ageing brain: relationship to Alzheimer's pathology and ApoE genotype. BRAIN PATHOLOGY, Vol. 20 (pp 46-46) RIS download Bibtex download
  • Nicholson S, Robson D, Jacques T, Wharton S, Michalski A, Pizer B, Bown N & Clifford S (2010) ESTABLISHMENT OF REAL-TIME CENTRALISED PATHOLOGY REVIEW (CPR) AND MOLECULAR DIAGNOSTICS FOR MEDULLOBLASTOMA IN THE UNITED KINGDOM. NEURO-ONCOLOGY, Vol. 12 (pp 6-6) RIS download Bibtex download
  • Nicholson SL, Robson K, Jaques T, Wharton SB, Michalski A, Pizer B, Bown N & Clifford SC (2010) ESTABLISHMENT OF REAL-TIME CENTRALISED PATHOLOGY REVIEW (CPR) AND MOLECULAR DIAGNOSTICS FOR MEDULLOBLASTOMA IN THE UNITED KINGDOM. NEURO-ONCOLOGY, Vol. 12(6) (pp II58-II58) RIS download Bibtex download
  • Langheinrich T, Romanowski C, Wharton S & Hadjivassiliou M (2010) Presenilin 1 S170P Mutation with a Limbic Encephalitis like Presentation. NEUROLOGY, Vol. 74(9) (pp A244-A244) RIS download Bibtex download
  • Langheinrich TC, Wharton S, Romanowski CAJ & Hadjivassiliou M (2009) . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 80(11) RIS download Bibtex download
  • Simpson JE, Ince PG, Theaker R, Haynes L, Forster G, Shaw PJ, Matthews F, Savva G, Brayne C, Wharton SB & MRC Cognitive Function & Ageing Ne (2009) Evidence of an astrocytic DNA damage response to oxidative stress in the ageing brain. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 35 (pp 18-19) RIS download Bibtex download
  • Lace G, Forster G, Savva G, Matthews F, Brayne C, De Silva R, Strong MJ, Ince PG & Wharton SB (2009) Variation in 4R and 3R tau isoforms in the ageing population. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 35 (pp 19-19) RIS download Bibtex download
  • Alafuzoff I, Al-Sarraj S, Arzberger T, Bodi I, Bogdanovic N, Budka H, Bugiani O, Boluda S, Duyckaerts C, Ferrer I , Gelpi E et al (2009) Reproducibility in the assessment of Alzheimer's disease and Lewy body disease-related pathologies: a study by Brain Net Europe. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 35 (pp 12-13) RIS download Bibtex download
  • Simpson J, Ince P, Theaker R, Haynes L, Forster G, Shaw P, Matthews F, Savva G, Brayne C & Wharton S (2008) DNA oxidative damage and repair mechanisms in astrocytes, and their relationship to Alzheimer-type pathology in the ageing brain. JOURNAL OF NEURAL TRANSMISSION, Vol. 115(12) (pp 1727-1727) RIS download Bibtex download
  • Lace GL, Savva G, Strong M, Ince PG, Forster G, Matthews F, Brayne C & Wharton SB (2008) Variation in 4R and 3R Tau isoforms in the ageing population. JOURNAL OF NEURAL TRANSMISSION, Vol. 115(12) (pp 1725-1726) RIS download Bibtex download
  • Harkness KAC, Langeinrich T & Wharton SB (2008) Optic neuropathy and cerebellar degeneration. JOURNAL OF NEUROIMMUNOLOGY, Vol. 197(2) (pp 175-175) RIS download Bibtex download
  • Simpson JE, Ince PG, Lace G, Forster G, Shaw PJ, Matthews F, Brayne C, Wharton SB & MRC Cognitive Function Ageing (2008) Characterisation of astrocytes in relation to Alzheimer-type pathology in the ageing brain using a population-based neuropathology cohort. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 34 (pp 31-31) RIS download Bibtex download
  • Wharton SB, Savva G, Ince PG, Matthews F, Brayne C & MRC-CFAS (2008) Age effects on the relationship between pathology and cognitive impairment in a population cohort. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 34 (pp 10-10) RIS download Bibtex download
  • Lace G, Forster G, Savva G, Barclay JJ, Dakin L, Matthews F, Brayne C, De Silva R, Ince PG, Wharton SB & MRC-CFAS (2008) Population variation in tau pathology in the MRC-CFAS neuropathology cohort. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 34 (pp 10-11) RIS download Bibtex download
  • Simpson JE, El-Sayed OH, Wharton SB, Heath P, Holden H, Forster G, Fernando MS, Matthews F, Brayne C, Lewis CE , Barber R et al (2008) Microarray gene expression analysis of deep subcortical lesions in the ageing brain reveals changes in multiple functional pathways. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 34 (pp 30-31) RIS download Bibtex download
  • Lace G, Ince PG, Matthews F, Brayne C, De Silva R & Wharton SB (2007) Population variation in tau pathology in the aged hippocampus in the MRC-CFAS neuropathology cohort. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 33(2) (pp 263-263) RIS download Bibtex download
  • Highley JR, Smith O, Brockington A, Kirby J, Wharton SB, Spillantini M, Lowe JS, Layfield R, Shaw PJ & Ince PG (2007) Extra-motor manifestations of motor neurone disease and the role of TDP43 in ALS variants. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 33(2) (pp 264-265) RIS download Bibtex download
  • Hosny O, Highley JR, Simpson JE, Forster G, Wharton SB & Ince PG (2007) Axonal number and myelin sheath degeneration in MRI hyperintense white matter lesions in the aging brain. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 33(2) (pp 266-267) RIS download Bibtex download
  • Simpson JE, El-Sayed OH, Wharton SB, Heath P, Holden H, Forster G, Fernando MS, Matthews F, Brayne C, Lewis CE , Barber R et al (2007) Microarray gene expression profiling of deep subcortical lesions in the ageing brain. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 33(2) (pp 254-255) RIS download Bibtex download
  • Simpson JE, Higham CE, Gelsthorpe CH, Fernando MS, Matthews F, Forster G, O'Brien JT, Barber R, Kalaria RN, Brayne C , Shaw PJ et al (2007) Microglial activation in white matter of the ageing brain. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 33(2) (pp 255-255) RIS download Bibtex download
  • Jellinek DA, Levy D, Maltby E, Atkey N, Hibberd S, Crimmins D, Stoeber K, Williams GH & Wharton SB (2006) Cytogenetic subtypes of oligodendroglioma differ in their apoptotic index, while the population of replication-licensed, non-proliferating cells is higher in anaplastic tumors but does not differ according to 1p,19q status. NEURO-ONCOLOGY, Vol. 8(4) (pp 459-459) RIS download Bibtex download
  • Atkey N, Wharton SB, Jellinek D & Maltby EL (2006) FISH for the detection of 1p and 19q deletions in oligodendrogioma paraffin wax sections - A retrospective study of 55 cases. JOURNAL OF MEDICAL GENETICS, Vol. 43 (pp S101-S101) RIS download Bibtex download
  • Ince PG, Fernando MS, Matthews F, Brayne C, Wharton SB, O'Brien JT, Lewis C, Kalaria RN, Shaw PJ & Simpson J (2006) Molecular markers of tissue hypoxia and glial pathology associated with incidental white matter lesions in the ageing brain. BRAIN PATHOLOGY, Vol. 16 (pp S92-S92) RIS download Bibtex download
  • Ince PG, Brayne C, Matthews F, Chatfield M, Esiri MM, Lowe JS & Wharton SB (2006) New pathological findings from the MRC-cognitive function and ageing study (CFAS) neuropathology cohort. BRAIN PATHOLOGY, Vol. 16 (pp S127-S127) RIS download Bibtex download
  • Simpson JE, Fernando MS, Matthews F, Brayne C, Lewis CE, Barber R, Kalaria RN, Forster G, Esteves F, Wharton SB , Shaw PJ et al (2006) Molecular markers of tissue hypoxia are associated with deep subcortical white matter lesions in the ageing brain. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 32(2) (pp 224-224) RIS download Bibtex download
  • Simpson JE, Fernando MS, Clark L, Ince PG, Matthews F, Forster G, O'Brien JT, Barber R, Kalaria RN, Brayne C , Shaw PJ et al (2006) Glial cell pathology of periventricular and deep white matter lesions in the ageing brain. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 32(2) (pp 224-225) RIS download Bibtex download
  • Owasil R, O鈥橬eill R, Keable A, Nimmo J, MacGregor Sharp M, Kelly L, Saito S, Simpson JE, Weller RO, Smith C , Attems J et al () . International Journal of Molecular Sciences, Vol. 21(4) (pp 1225-1225) RIS download Bibtex download

Datasets

  • Appleby-Mallinder C, Schaber E, Kirby J, Shaw P, Cooper-Knock J, Wharton S, Heath P & Highley JR . RIS download Bibtex download

Preprints

  • Xia Z, Prescott E, Wareing H, Matuszyk M, Dakin H, Dimou E, Hidari E, Zhang Y, Lam J, Danial J , Leah T et al (2022) , Research Square Platform LLC. RIS download Bibtex download
  • Rajab MD, Jammeh E, Taketa T, Brayne C, Matthews FE, Su L, Ince PG, Wharton SB & Wang D (2022) , Research Square. RIS download Bibtex download
  • Rajab M, Jammeh E, Taketa T, Brayne C, Matthews F, Su L, Ince P, Wharton S & Wang D (2022) , medRxiv. RIS download Bibtex download
  • Xia Z, Prescott EE, Wareing HE, Matuszyk MM, Dakin H, Dimou E, Zuo E, Zhang YP, Lam JYL, Danial JSH , Leah T et al (2021) , Cold Spring Harbor Laboratory. RIS download Bibtex download
  • Williamson D, Schwalbe EC, Hicks D, Aldinger KA, Lindsey JC, Crosier S, Richardson S, Goddard J, Hill RM, Castle J , Grabovska Y et al () , Cold Spring Harbor Laboratory. RIS download Bibtex download
  • Perez-Nievas BG, Johnson L, Beltran-Lobo P, Hughes MM, Gammallieri L, Tarsitano F, Myszczynska MA, Vazquez-Villasenor I, Jimenez-Sanchez M, Troakes C , Wharton SB et al () , Cold Spring Harbor Laboratory. RIS download Bibtex download
  • Shabir O, Sharp P, Rebollar MA, Boorman L, Howarth C, Wharton SB, Francis SE & Berwick J () , Cold Spring Harbor Laboratory. RIS download Bibtex download
Research group

Current PhD students:

  • Harriet Brooke

Research team:

  • Dr Bridget Ashford
  • Dr Bridget Benson
  • Mr Saif Ahamed
Grants

Current funding sources

  • Alzheimer鈥檚 Society
  • Alzheimer鈥檚 Research UK
  • British Heart Foundation
Teaching interests
  • Module leader: Neurodegeneration module, MSc Translational Neuroscience
  • MSc lectures 鈥 Translational Neuroscience
  • MBBS lectures 鈥 Preclinical neurosciences
  • Neuroanatomy dissection teaching
  • Supervisor SSC research projects
  • Supervisor MSc research projects
  • Seminars to postgraduate trainees in histopathology and clinical neurosciences
Professional activities and memberships

Editorial activities

  • Consulting editor, Neuropathology and Applied Neurobiology (2014-7)
  • Editor-in-Chief, Neuropathology and Applied Neurobiology (2007-13)

External professional activities 鈥 current and recent

  • President of the British Neuropathological Society (2022 鈥 2024)
  • Vice-president of the British Neuropathological Society (2020-2022)
  • Member of the annual review panel for Brains for Dementia Research (2022 鈥 present)
  • Member of the Alzheimer鈥檚 Research UK Grant Review Board 2016- 2022
  • Chair of the specialist advisory committee in neuropathology, Royal College of Pathologists, 2020-2022
  • Chief of panel of examiners in neuropathology for the Royal College of Pathologists (2018-21)
  • Examiner in neuropathology for the Royal College of Pathologists (2005-21)

Membership of associations and societies - current

  • International Society for Neuropathology
  • British Neuropathological Society
Current projects

Neuronal Senescence as a Contributory Mechanism to Dementia

Funded by Alzheimer's Research UK, this project aims to study the contribution of neuronal senescence to dementia. Markers of dementia, such as tangles and plaques that characterise Alzheimer鈥檚, do not explain all dementia, and treatments aimed at them have been unsuccessful. This suggests other processes contribute to dementia.

Senescent cells, sometimes called zombie cells, are persistently damaged cells, often because of damage to their DNA, which carries all the instructions for the cell. These cells remain alive, but they do not carry out their normal functions. Additionally, they produce factors that damage nearby cells and cause inflammation. Zombie cells are described in other tissues and diseases and there are drug treatments aimed at them. However, their role in dementia is not understood. Using brain tissue samples from the Cognitive Function and Ageing Study, we plan to identify senescent nerve cells in the brain and determine how they relate to dementia.

To determine how senescence causes damage, we will isolate nerve cells with and without markers of senescence from the same cases, and investigate effects on the cells by determining differences in the gene messages present. This will provide greater understanding of how senescence contributes to dementia and identify specific ways in which senescence affects nerve cells, which may lead us to new approaches to target zombie cells.

How does brain microvascular disease, especially pathological changes to capillaries, contribute to dementia?

Studies of blood vessel diseases, the second commonest cause of dementia, have focused mainly on large or small arteries. However, the contribution of pathology affecting the smallest vessels, the capillaries, is not understood. Brain capillaries are specialised to ensure that substances entering the brain from the blood are tightly-regulated and that blood supply is matched to the needs of nerve cells. This study, funded by the British Heart Foundation, will investigate the contribution of microvascular disease (MVD), affecting the capillaries, to dementia. Using donated human brain tissue, we will first characterise MVD using immunohistochemistry, a method that allows us to identify whether and where particular molecules are expressed and to measure them using a computer. Secondly, we will determine how these new MVD measures compare to other, existing measures of dementia-related pathologies. Thirdly, we will extend the assessment of the most informative MVD measures to all 550 donations, then determine how MVD contributes to dementia using advanced statistical methods. Lastly, we will identify potential new mechanisms of capillary damage by examining the expression of all the messages (mRNA) that code for protein production in the capillaries. Computer-based approaches will allow us to analyse this data to identify changes in cell processes that contribute to disease.

What is the Contribution of Basal Ganglia Pathology to Late-life Dementia and Frailty?

Most studies of dementia focused on the cerebral cortex, but other brain regions are also important. This PhD studentship, funded by the Alzheimer鈥檚 Society, aims to investigate how pathology in the basal ganglia contributes to dementia and frailty in late-life. The basal ganglia have many connections to the cortex and are involved in cognition as well as in motor control. They are affected by vascular disease and in the progression of Alzheimer鈥檚 disease. We plan to use human autopsy brain tissue samples donated as part of the Cognitive Function and Ageing Study. We will characterised vascular pathology and neurodegenerative pathology in basal ganglia using microscopy and immunohistochemistry. We will then determine the contribution that pathology in the basal ganglia makes to dementia and also to frailty. Finally, we will use gene expression analysis  to determine new pathways by which pathology in basal ganglia might damage the function of this tissue.