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Thermo Scientific

(Part of Thermo Fisher Scientific)

Thermo Fisher Scientific is a leading provider in the analytical and laboratory technologies industry, helping the pharmaceutical industry drive innovation and productivity. Our products and services can help you make your drug discovery and development processes faster and more efficient. Our material characterisation solutions offer features and benefits that can span the pharmaceutical market from formulation to manufacturing.

We use continuous processes to allow reliable, one-step scale-up from development to production. If your company’s projects involve any of the following then we can help solve your pharmaceutical challenges:

• Hot melt extrusion
• Continuous granulation 
• GMP extrusion 
• Online optical spectroscopy
• Analysis of rheological properties and microscopic structure 
• Investigating viscoelastic or extensional flow behaviours 

Visit our stand to take a closer look at our new Thermo Scientific Pharma 11 – a unique, flexible twin screw extruder for hot melt extrusion and twin screw granulation - helping scientists in the early development of new drug research and development formulation.

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Glatt

Integrated Process Solutions - that is our philosophy.

The name Glatt brings together four areas of expertise in an integrated portfolio with solutions for your processes. Individual and all-inclusive.

You have an idea. We support you along the entire value chain — from formulation to the seamless turn-key solution, from product development to the necessary process technologies, right up to the construction of an entire plant. With our quality products and services, innovative technologies and complete service, we always keep the big picture. Take advantage of our unique, complete expertise. All-inclusive from a single source. To make your business a success.

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Retsch UK Ltd

Solutions in Milling & Sieving

Retsch is active in the fields of homogenizing laboratory samples for analysis as well as particle size analysis of solid substances. On the basis of more than 90 years' experience we have developed into the leading instrument manufacturer in these technologies.

Retsch instruments are used in science and industry for preparing samples for a wide range of different analytical methods as well as for particle size analysis in the context of production control and quality monitoring.

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Alexanderwerk & Orthos Engineering

The Alexanderwerk Group specialise in the development and production of compaction and granulation machines for the chemical and pharmaceutical industries, to convert poor-flowing powders into free-flowing granules of higher density. Consequently:

• Granular materials are more easily and accurately dosed (e. g. feeding into tablet presses)
• Less dust occurs inside machines or working spaces; resulting in lower OEL’s and subsequent reduced health risks to operators. The noticeable reduction in dust also results in extended machine life of the final form machinery.
• Solubility or dispersion rates are often improved by the formation of the compacted granulates.
• Homogeneous distribution of the active substance.

With their WP 120 Pharma unit (as seen at University of ��«Ӱҵ) Alexanderwerk offers a roller compactor specifically designed for use in R&D departments or small scale production. Even batches of as little as 5g can be processed on the WP 120 Pharma.

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Freeman Technology

Freeman Technology specialises in systems for measuring the flow properties of powders and has over a decade of experience in powder flow and powder characterisation. The company invests significantly in R&D and applications development, and provides detailed know-how alongside its universal powder tester, the FT4 Powder Rheometer®. Expert teams guide and support users around the world in addressing their individual powder challenges, focusing on delivering the most relevant information for the process. The result is world-leading solutions for understanding powder behaviour - in development, formulation, scale-up, processing, quality control, or anywhere that powders have a role.

The FT4 Powder Rheometer uses patented dynamic methodology, a fully automated shear cell and several bulk property tests, including density, compressibility and permeability, to quantify powder properties in terms of flow and processability. Systems are installed around the world in the chemical, pharmaceutical, toners, foods, powder coatings, metals, ceramics, cosmetics, and many other, industries. They deliver data that maximise process and product understanding, accelerating R&D and formulation towards successful commercialisation, and supporting the long term optimisation of powder processes.

Freeman Technology was founded in 1989 as a developer of automated testing systems for materials characterisation, and has focused exclusively on powders since the late 1990s. The company’s R&D, manufacturing and commercial headquarters are in Gloucestershire, UK, with operations in the USA and China, and distribution partners in Brazil, France, India, Ireland, Japan, Malaysia, Singapore, Taiwan and Thailand.

In 2007 the company received the Queen’s Award for Enterprise in Innovation and in 2012 the Queen’s Award for Enterprise in International Trade.

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S3 Process

Continuously Improving Process Manufacturing

S3 Process supplies the leading process equipment to pharmaceutical manufacturers throughout the UK and Ireland. With our experienced team of consultants and project managers, we support clients through design, build, testing, installation and validation to ensure every piece of process equipment is delivered as part of a fully integrated solution.

Committed to the continuous improvement of process manufacturing, we cooperate with clients to identify process innovations that can deliver tangible efficiencies. Combining the very best process equipment with innovative techniques, our clients see significant improvements in quality, scale-up and production times, manufacturing costs, personal safety and overall manufacturing sustainability.

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Innopharma labs

Seeing the Unseen

Innopharma Labs develop efficient, reliable and rapid direct measurement PAT analysers that support research, development and investigational experiments resulting in greater knowledge and more robust manufacturing processes. Innopharma Labs products provide high quality data and images to understand processes such as blending, granulation, coating, roller compaction/milling, compression, fluid bed granulation, spheronisation and packaging in greater detail helping to reduce time to generate experimental data, scale-up time and product losses resulting on improved yields.

Technologies:

On-Line/At-Line Real-time 3D Particle Characterisation

Eyecon™ is a non-invasive, real-time 3D particle characteriser capable of giving live particle size and shape information. It increases process understanding and subsequently control for granulation, milling, and spheronisation processes. Unique instrument features include:

• non-product contact
• on-line or at-line configuration
• real time size & shape data & images
• intuitive and user friendly interface
• portable

On-Line Real-Time Multi-point NIR Imaging

MultiEye™ provides a system for live monitoring of blend homogeneity on a chemical level. Using multiple single-point probes placed at different points within a blender, mixer or granulator, Multieye™ provides a live view of the concentrations of APIs and excipients at each location and to assist in detecting process end points. Other applications include precise monitoring of the moisture content within granulation processes, and the monitoring of ribbon density in roller compaction.

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ProCepT

Particle Processing Equipment & Service Provider

ProCepT has 20 years’ experience in particle processing technology.
We specialize in development of lab-scale R&D equipment (mg to kg).
We supply process equipment; Spray Dryer - Congealer / Fluidbed / Tablet Coater / High Shear Granulator - Vacuum Dryer / Extruder / Nutsche Filter Dryer.
Our engineering concept is based on Modularity, Visibility, Accuracy and Customization.

Xedev, a spin out from ProCepT, is a Service Provider in Particle Engineering and Process Development, operating under a “fee for service” principle.
We make the difference by combining expertise in Process, Formulation and Analytics with Equipment Engineering.
Xedev offers services from a one day process feasibility run to complete process & formulation development, technology transfer, scale-up and analytical support.
ProCepT and Xedev support Pharma, Biotech, Chemical, Food, Cosmetic and Agro industries.

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NeuhausNeotec

Specialist in particle technology:

• Continuous fluid bed plants
• Batch fluid bed technology
• Roll grinders

Neuhaus Neotec specialises in building plants for the food industry, the fine chemistry, the chemical and the pharmaceutical industries. In mechanical engineering for the processing of coffee, we are one of the world's leading manufacturers. With the takeover of the company Heinen Drying in 2010, we have expanded our business area "Particle technology". Based on this extensive know-how we develop fluidised bed plants for continuous as well as discontinuous (batch) operation.

• Fluid bed drying
• Agglomeration
• Spray drying agglomeration
• Fluid bed spray granulation
• Coating
• Micro-encapsulation

In our professional pilot plant, we simulate your individual requirements on a laboratory scale, optimise product properties and test process parameters for large production plants.

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Microtrac

Total Solutions in Particle Characterisation

Microtrac strives to provide the materials characterisation world with innovative, reliable, and repeatable particle size, particle shape, particle charge, and surface area analysis instrumentation.

Microtrac’s instruments deliver insight and solutions to the complex product and process problems a company may experience.

Particle analysis instruments are used in Virtually Every Industry, from pharmaceutical to food processing, even extending to such novel applications as analysis of interplanetary materials like moon rock.

Microtrac particle characterisation instruments are used by top industry professionals to conduct the following analysis:

• Particle Size Measurements
• Zeta Potential Analysis
• 3-D Image Analysis
• Molecular Weight
• Surface Analysis
• Particle Counting
• Dust Characterisation

Whether you are new to the industry or a seasoned veteran, you will be able to find a solution to fit your specific needs at Microtrac.

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Surface Measurement Systems Ltd.

Surface Measurement Systems develops and engineers innovative experimental techniques and instrumentation for physico-chemical characterisation of solid state materials.

We are the world leaders in Dynamic Vapor Sorption technology and Inverse Gas Chromatography instrumentation and solutions, providing professional world-class scientific and technical support for our international customers.

Inverse Gas Chromatography - Surface Energy Analyzer (iGC-SEA)
This system is specially designed to determine the surface energy heterogeneity but nevertheless suitable for measuring different surface and bulk properties of solid materials including acid / base properties, heat of sorption, glass transition temperature, solubility parameters and so on.

Dynamic Vapour Sorption (DVS)
This system allows for real-time monitoring and controlling of vapor and gas concentration for sorption measurements in solid state materials. The sorption mechanism may be investigated from sorption / desorption isotherms and hysteresis effects. The combination of a video microscope and vibrational spectroscopic techniques with DVS would allow for increased understanding of vapor-induced structural changes of solid materials. The DVS Vacuum can offer measurements on vapour pressure and heat of evaporation of solids, low pressure vapour/gas sorption and vacuum drying.

Humidity Generation Systems (GenRH)
This system allows for precise humidity generation and delivery to sample enclosures and multiple analytical techniques including microscopy stage and FT – IR.